{"id":3535,"date":"2026-10-05T16:07:10","date_gmt":"2026-10-05T16:07:10","guid":{"rendered":"https:\/\/nhdbio.com\/?p=3535"},"modified":"2026-10-09T08:31:27","modified_gmt":"2026-10-09T08:31:27","slug":"ss31-%d8%b4%d8%b1%d8%ad-%d8%a2%d9%84%d9%8a%d8%a9-%d8%b7%d8%a7%d9%82%d8%a9-%d8%a7%d9%84%d9%85%d9%8a%d8%aa%d9%88%d9%83%d9%88%d9%86%d8%af%d8%b1%d9%8a%d8%a7-%d9%84%d9%84%d9%83%d8%a7%d8%b1%d8%af%d9%8a","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ar\/ss31-cardiolipin-mitochondrial-energy-mechanism-explained\/","title":{"rendered":"SS-31 \u0648\u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0629: \u0639\u0644\u0627\u0642\u0629 \u0627\u0644\u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u0628\u0630\u0644\u0643"},"content":{"rendered":"<p>\u064a\u064f\u062f\u0631\u0633 SS-31 \u0645\u0646 \u0623\u062c\u0644 \u062a\u0641\u0627\u0639\u0644\u0647 \u0645\u0639 \u062f\u0647\u0646 \u064a\u064f\u0633\u0645\u0649 \u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u0641\u064a \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a \u0627\u0644\u062f\u0627\u062e\u0644\u064a. \u064a\u0634\u0631\u062d \u0647\u0630\u0627 \u0627\u0644\u062f\u0644\u064a\u0644 \u062a\u0644\u0643 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u0644\u063a\u0629 \u0645\u0628\u0633\u0637\u0629\u060c \u062b\u0645 \u064a\u0641\u0635\u0644 \u0628\u064a\u0646 \u0627\u0644\u0622\u0644\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0642\u0627\u0633\u0629 \u0641\u064a \u0643\u0644 \u062a\u062c\u0631\u0628\u0629.<\/p>\n<h2>\u0627\u0628\u062f\u0623 \u0628\u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0645\u0646\u062a\u062c \u0644\u0644\u0637\u0627\u0642\u0629<\/h2>\n<p>\u062a\u0633\u0627\u0639\u062f \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0639\u0644\u0649 \u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0627\u0644\u063a\u0630\u0627\u0626\u064a\u0629 \u0625\u0644\u0649 \u0637\u0627\u0642\u0629 \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645. ATP \u0647\u0648 \u0623\u062d\u062f \u0627\u0644\u062c\u0632\u064a\u0626\u0627\u062a \u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629 \u0627\u0644\u0645\u0633\u062a\u062e\u062f\u0645\u0629 \u0644\u0646\u0642\u0644 \u062a\u0644\u0643 \u0627\u0644\u0637\u0627\u0642\u0629. \u0645\u0646 \u0627\u0644\u0645\u0641\u064a\u062f \u062a\u0634\u0628\u064a\u0647 \u0630\u0644\u0643 \u0628\u062e\u0637 \u062a\u062c\u0645\u064a\u0639: \u062a\u0645\u0631 \u0639\u062f\u0629 \u062e\u0637\u0648\u0627\u062a \u0645\u062a\u0631\u0627\u0628\u0637\u0629 \u0628\u0627\u0644\u0625\u0644\u0643\u062a\u0631\u0648\u0646\u0627\u062a \u0639\u0644\u0649 \u0637\u0648\u0644 \u0627\u0644\u0633\u0644\u0633\u0644\u0629\u060c \u0645\u0645\u0627 \u064a\u0633\u0627\u0639\u062f \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c ATP. \u0625\u0630\u0627 \u062a\u063a\u064a\u0631 \u062c\u0632\u0621 \u0648\u0627\u062d\u062f \u0645\u0646 \u062a\u0644\u0643 \u0627\u0644\u0633\u0644\u0633\u0644\u0629\u060c \u0641\u0642\u062f \u064a\u0638\u0647\u0631 \u0630\u0644\u0643 \u0643\u0646\u062a\u064a\u062c\u0629 \u0639\u0644\u0649 \u0634\u0643\u0644 \u062a\u063a\u064a\u0631 \u0641\u064a \u0627\u0633\u062a\u0647\u0644\u0627\u0643 \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0623\u0648 \u0625\u0646\u062a\u0627\u062c ATP. \u062a\u062e\u0628\u0631 \u062a\u0644\u0643 \u0627\u0644\u0642\u064a\u0627\u0633\u0627\u062a \u0627\u0644\u0628\u0627\u062d\u062b\u064a\u0646 \u0639\u0646 \u0627\u0644\u0646\u0638\u0627\u0645 \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u061b \u0648\u0647\u064a \u0644\u064a\u0633\u062a \u0645\u0642\u064a\u0627\u0633\u064b\u0627 \u0645\u0628\u0627\u0634\u0631\u064b\u0627 \u0644\u0645\u0642\u062f\u0627\u0631 \u0627\u0644\u0646\u0634\u0627\u0637 \u0623\u0648 \u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062a\u064a \u064a\u0634\u0639\u0631 \u0628\u0647\u0627 \u0627\u0644\u0634\u062e\u0635.<\/p>\n<h2>\u0627\u0644\u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u062c\u0632\u0621 \u0645\u0646 \u0627\u0644\u063a\u0634\u0627\u0621\u060c \u0648\u0644\u064a\u0633 \u0628\u0628\u062a\u064a\u062f\u064b\u0627 \u0622\u062e\u0631<\/h2>\n<p>\u0627\u0644\u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u062f\u0647\u0646 \u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u062f\u0627\u062e\u0644\u064a \u0644\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627. SS-31 \u0647\u0648 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0642\u064a\u062f \u0627\u0644\u062f\u0631\u0627\u0633\u0629. \u0627\u0633\u062a\u062e\u062f\u0645\u062a \u062f\u0631\u0627\u0633\u0629 \u0628\u064a\u0631\u0643 2014 \u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u063a\u0634\u0627\u0626\u064a\u0629 \u0627\u0635\u0637\u0646\u0627\u0639\u064a\u0629 \u0648\u0645\u0633\u062a\u062d\u0636\u0631\u0627\u062a \u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0629 \u0644\u0641\u062d\u0635 \u062a\u0641\u0627\u0639\u0644\u0647\u0645\u0627. \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u0625\u0639\u062f\u0627\u062f\u060c \u0623\u0628\u0644\u063a \u0627\u0644\u0628\u0627\u062d\u062b\u0648\u0646 \u0639\u0646 \u0646\u0633\u0628\u0629 \u062a\u0641\u0627\u0639\u0644 \u062a\u0642\u0627\u0631\u0628 1:1. \u064a\u0635\u0641 \u0627\u0644\u0631\u0642\u0645 \u062a\u0641\u0627\u0639\u0644\u064b\u0627 \u062c\u0632\u064a\u0626\u064a\u064b\u0627 \u0641\u064a \u0627\u0644\u062a\u062c\u0631\u0628\u0629. \u0648\u0647\u0648 \u0644\u064a\u0633 \u062a\u0639\u0644\u064a\u0645\u0629 \u062e\u0644\u0637 \u0623\u0648 \u0643\u0645\u064a\u0629 \u0645\u0648\u0635\u0649 \u0628\u0647\u0627 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645.<\/p>\n<h2>\u064a\u0645\u0643\u0646 \u0644\u0628\u0631\u0648\u062a\u064a\u0646 \u0648\u0627\u062d\u062f \u0623\u0646 \u064a\u062a\u0635\u0631\u0641 \u0628\u0637\u0631\u064a\u0642\u062a\u064a\u0646 \u0645\u062e\u062a\u0644\u0641\u062a\u064a\u0646<\/h2>\n<p>Cytochrome c normally participates in electron transfer. Under particular interactions with cardiolipin, it can also show peroxidase activity, involving oxidation reactions. Birk and colleagues reported that SS-31 limited that peroxidase behavior while helping preserve electron transfer. Their mitochondrial experiments also measured respiration and ATP synthesis. This is the more precise research story behind the loose phrase \u201csupports mitochondrial energy.\u201d <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24134698\/\">\u0627\u0642\u0631\u0623 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0623\u0635\u0644\u064a\u0629<\/a>.<\/p>\n<figure class=\"wp-block-image\"><a href=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/ss31-diagram.png\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/ss31-diagram.png\" alt=\"\u0645\u062e\u0637\u0637 \u0645\u0628\u0633\u0637 \u0644\u0640 SS-31\u060c \u0648\u0627\u0644\u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646\u060c \u0648\u0627\u0644\u0633\u064a\u062a\u0648\u0643\u0631\u0648\u0645 c\u060c \u0648\u0642\u0631\u0627\u0621\u0627\u062a \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627 \u0627\u0644\u062a\u062c\u0631\u064a\u0628\u064a\u0629.\" width=\"1600\" height=\"900\" loading=\"lazy\" style=\"width:100%;height:auto\"><\/a><figcaption>\u0645\u062e\u0637\u0637 \u0628\u062d\u062b\u064a \u0645\u0628\u0633\u0637: \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u063a\u0634\u0627\u0621\u060c \u0648\u0646\u0642\u0644 \u0627\u0644\u0625\u0644\u0643\u062a\u0631\u0648\u0646\u060c \u0648\u0642\u064a\u0627\u0633\u0627\u062a ATP \u0647\u064a \u062e\u0637\u0648\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629. \u0627\u0646\u0642\u0631 \u0639\u0644\u0649 \u0627\u0644\u0635\u0648\u0631\u0629 \u0644\u0639\u0631\u0636\u0647\u0627 \u0628\u0627\u0644\u062d\u062c\u0645 \u0627\u0644\u0643\u0627\u0645\u0644.<\/figcaption><\/figure>\n<h2>\u0644\u0645\u0627\u0630\u0627 \u064a\u0645\u0643\u0646 \u0623\u0646 \u064a\u0636\u0644\u0644 \u0631\u0642\u0645 \u0641\u0639\u0627\u0644\u064a\u0629 \u0648\u0627\u062d\u062f<\/h2>\n<p>A related 2013 paper reported a peroxidase-inhibition EC50 of 3.5 \u00b1 0.03 micromolar in one cell-free setup, versus 0.8 \u00b1 0.06 micromolar in permeabilized mitochondria. EC50 means the concentration associated with half of the measured maximal effect in that assay. The two values concern different experimental settings. They do not show that SS-31 has one fixed potency in every cell, tissue or person. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23813215\/\">\u0627\u0642\u0631\u0623 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629<\/a>.<\/p>\n<h2>\u0627\u0642\u0631\u0623 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0628\u062c\u0627\u0646\u0628 \u0627\u0644\u0646\u0645\u0648\u0630\u062c<\/h2>\n<p>\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0648\u0631\u0642\u0629 \u0628\u062d\u062b\u064a\u0629 \u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0637\u0627\u0642\u0629\u060c \u0627\u0633\u0623\u0644 \u0645\u0627 \u0627\u0644\u0630\u064a \u0642\u0627\u0633\u0647 \u0627\u0644\u0645\u0624\u0644\u0641\u0648\u0646: \u0627\u0633\u062a\u0647\u0644\u0627\u0643 \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646\u060c \u0623\u0648 \u0625\u0646\u062a\u0627\u062c ATP\u060c \u0623\u0648 \u062e\u0635\u0627\u0626\u0635 \u0627\u0644\u063a\u0634\u0627\u0621\u060c \u0623\u0648 \u0646\u062a\u064a\u062c\u0629 \u0633\u0631\u064a\u0631\u064a\u0629. \u062a\u0646\u062a\u0645\u064a \u0647\u0630\u0647 \u0627\u0644\u0646\u0642\u0627\u0637 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u0629 \u0625\u0644\u0649 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0645\u062e\u062a\u0644\u0641\u0629 \u0645\u0646 \u0627\u0644\u0623\u062f\u0644\u0629. \u062a\u062d\u0642\u0642 \u0623\u064a\u0636\u064b\u0627 \u0645\u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u062a\u062d\u0633\u0646 \u0627\u0644\u0645\u064f\u0628\u0644\u064e\u0651\u063a \u0639\u0646\u0647 \u0642\u062f \u062d\u062f\u062b \u062a\u062d\u062a \u0638\u0631\u0641 \u062a\u062d\u062f\u064d\u0651 \u0623\u0645 \u0639\u0646\u062f \u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633. \u0627\u0644\u062a\u063a\u064a\u0631 \u0641\u064a \u0645\u0633\u062a\u062d\u0636\u0631 \u0645\u064a\u062a\u0648\u0643\u0646\u062f\u0631\u064a \u0645\u0639\u0632\u0648\u0644 \u0644\u0627 \u064a\u062b\u0628\u062a \u0628\u062d\u062f \u0630\u0627\u062a\u0647 \u062a\u062d\u0633\u0646\u064b\u0627 \u0641\u064a \u0627\u0644\u062a\u0639\u0628 \u0627\u0644\u0628\u0634\u0631\u064a \u0623\u0648 \u0623\u062f\u0627\u0621 \u0627\u0644\u062a\u0645\u0627\u0631\u064a\u0646 \u0623\u0648 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629.<\/p>\n<h2>\u0643\u064a\u0641 \u064a\u062a\u0635\u0644 \u0647\u0630\u0627 \u0628\u0627\u0633\u062a\u0641\u0633\u0627\u0631 SS-31<\/h2>\n<p>\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0645\u0634\u0631\u0648\u0639 \u0645\u062e\u062a\u0628\u0631\u064a\u060c \u062a\u0643\u0648\u0646 \u0627\u0644\u0645\u062d\u0627\u062f\u062b\u0629 \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629 \u062d\u0648\u0644 \u0634\u0643\u0644 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0627\u0644\u0645\u062d\u062f\u062f \u0648\u0627\u0644\u0633\u062c\u0644\u0627\u062a \u0627\u0644\u062f\u0627\u0639\u0645\u0629 \u0644\u0647\u0648\u064a\u0629 \u0627\u0644\u0645\u0627\u062f\u0629. \u0635\u0641 \u0633\u0624\u0627\u0644 \u0628\u062d\u062b\u0643 \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0627\u0644\u0643\u0645\u064a\u0629 \u0627\u0644\u0645\u0637\u0644\u0648\u0628\u0629 \u0648\u0627\u0644\u0646\u0637\u0627\u0642 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a. \u0644\u0645\u0646\u0627\u0642\u0634\u0629 \u0645\u0646\u0641\u0635\u0644\u0629 \u0644\u0644\u0633\u064a\u0627\u0642 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0648\u0633\u064a\u0627\u0642 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u060c \u0631\u0627\u062c\u0639 <a href=\"https:\/\/nhdbio.com\/ar\/%d8%a7%d9%84%d9%82%d8%b3%d9%85-31-%d8%a5%d9%8a%d9%84%d8%a7%d9%85%d9%8a%d8%a8%d8%b1%d9%8a%d8%aa%d9%8a%d8%af-%d9%85%d9%82%d8%a7%d8%a8%d9%84-%d9%81%d9%88%d8%b1%d8%b2%d9%8a%d9%86%d9%8a%d8%aa%d9%8a\/\">\u062f\u0644\u064a\u0644 \u0623\u062f\u0644\u0629 SS-31 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a<\/a>. \u0644\u0627 \u064a\u0646\u0628\u063a\u064a \u0627\u0644\u062a\u0639\u0627\u0645\u0644 \u0645\u0639 \u0623\u062f\u0644\u0629 \u0627\u0644\u062a\u0631\u0643\u064a\u0628\u0627\u062a \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0643\u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u062f\u0641\u0639\u0629 \u0628\u062d\u062b\u064a\u0629 \u0641\u064a \u0627\u0644\u0643\u062a\u0627\u0644\u0648\u062c.<\/p>\n<section id=\"nhd-reader-guide-20261009\">\n<h2>\u0645\u0646 \u062a\u0641\u0627\u0639\u0644 \u0627\u0644\u063a\u0634\u0627\u0621 \u0625\u0644\u0649 \u0646\u062a\u064a\u062c\u0629 \u0645\u0642\u0627\u0633\u0629<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u062a\u062d\u0642\u0642<\/th>\n<th>\u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u062e\u0628\u0631\u0643 \u0628\u0647<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u0622\u0644\u064a\u0629<\/td>\n<td>\u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0645\u0639 \u0627\u0644\u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u064a\u0633\u0627\u0639\u062f \u0641\u064a \u062a\u0641\u0633\u064a\u0631 \u0633\u0628\u0628 \u062f\u0631\u0627\u0633\u0629 \u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a\u0627.<\/td>\n<\/tr>\n<tr>\n<td>\u0646\u0642\u0637\u0629 \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u0645\u062e\u0628\u0631\u064a\u0629<\/td>\n<td>\u0642\u062f \u062a\u0642\u064a\u0633 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0633\u0644\u0648\u0643 \u0627\u0644\u063a\u0634\u0627\u0621 \u0623\u0648 \u0627\u0644\u062a\u0646\u0641\u0633 \u0623\u0648 \u0625\u0634\u0627\u0631\u0629 \u0623\u062e\u0631\u0649 \u0645\u062d\u062f\u062f\u0629.<\/td>\n<\/tr>\n<tr>\n<td>\u0646\u0642\u0637\u0629 \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/td>\n<td>\u064a\u062c\u0628 \u0623\u0646 \u062a\u0642\u064a\u0633 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u0631\u0636\u0649 \u0646\u062a\u064a\u062c\u062a\u0647\u0627 \u0627\u0644\u062e\u0627\u0635\u0629\u061b \u0648\u0644\u0627 \u062a\u062d\u0644 \u0627\u0644\u0622\u0644\u064a\u0629 \u0645\u062d\u0644 \u0630\u0644\u0643.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u0644\u0623\u063a\u0631\u0627\u0636 \u0627\u0644\u0634\u0631\u0627\u0621 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a\u060c <a href=\"https:\/\/nhdbio.com\/ar\/%d8%a7%d9%84%d9%85%d9%86%d8%aa%d8%ac%d8%a7%d8%aa\/ss-31-%d8%a5%d9%8a%d9%84%d8%a7%d9%85%d9%8a%d8%a8%d8%b1%d9%8a%d8%aa%d9%8a%d8%af\/\">\u0631\u0627\u062c\u0639 \u0645\u0627\u062f\u0629 \u0627\u0644\u0643\u062a\u0627\u0644\u0648\u062c \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629 NHD<\/a> \u0648\u062a\u0623\u0643\u062f \u0645\u0646 \u0627\u0644\u0645\u062a\u063a\u064a\u0631 \u0627\u0644\u0645\u062e\u062a\u0627\u0631 \u0648\u0623\u0633\u0627\u0633 \u0627\u0644\u0643\u0645\u064a\u0629 \u0648\u0627\u0644\u0633\u062c\u0644\u0627\u062a \u0627\u0644\u0645\u062a\u0627\u062d\u0629. <a href=\"https:\/\/nhdbio.com\/ar\/%d8%a7%d9%82%d8%aa%d8%a8%d8%a7%d8%b3\/\">\u0623\u0631\u0633\u0644 \u0627\u0633\u062a\u0641\u0633\u0627\u0631\u064b\u0627 \u0628\u062d\u062b\u064a\u064b\u0627<\/a> \u0645\u0639 \u062a\u0644\u0643 \u0627\u0644\u0645\u062a\u0637\u0644\u0628\u0627\u062a\u061b \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0645\u0630\u0643\u0648\u0631\u0629 \u0644\u064a\u0633\u062a \u0627\u062e\u062a\u0628\u0627\u0631\u064b\u0627 \u0644\u062f\u0641\u0639\u0629 NHD.<\/p>\n<\/section>\n<h2>\u0627\u0633\u062a\u0643\u0634\u0641 \u0645\u0646\u062a\u062c NHD \u0630\u064a \u0627\u0644\u0635\u0644\u0629<\/h2>\n<p>\u0627\u0646\u0638\u0631 \u0625\u0644\u0649 <a href=\"https:\/\/nhdbio.com\/ar\/%d8%a7%d9%84%d9%85%d9%86%d8%aa%d8%ac%d8%a7%d8%aa\/ss-31-%d8%a5%d9%8a%d9%84%d8%a7%d9%85%d9%8a%d8%a8%d8%b1%d9%8a%d8%aa%d9%8a%d8%af\/\">\u0633\u062c\u0644 \u0645\u0646\u062a\u062c SS-31 (Elamipretide)<\/a> \u0644\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0643\u062a\u0627\u0644\u0648\u062c. <a href=\"https:\/\/nhdbio.com\/ar\/%d8%a7%d9%82%d8%aa%d8%a8%d8%a7%d8%b3\/\">\u0623\u0631\u0633\u0644 \u0627\u0644\u0643\u0645\u064a\u0629 \u0648\u0645\u062a\u0637\u0644\u0628\u0627\u062a \u0627\u0644\u0645\u0633\u062a\u0646\u062f\u0627\u062a \u0644\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0639\u0631\u0636 \u0633\u0639\u0631<\/a>. \u064a\u062c\u0628 \u062a\u0623\u0643\u064a\u062f \u0627\u0644\u062a\u0648\u0641\u0631 \u0648\u0646\u0637\u0627\u0642 \u0623\u064a \u0645\u0633\u062a\u0646\u062f\u0627\u062a \u0644\u0644\u062f\u0641\u0639\u0629.<\/p>\n<h2>\u0627\u0644\u062f\u0631\u0627\u0633\u0627\u062a \u0627\u0644\u0623\u0635\u0644\u064a\u0629<\/h2>\n<ul>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24134698\/\">Cardiolipin interaction, electron transport and ATP synthesis \u2014 2014 original paper<\/a><\/li>\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23813215\/\">Peroxidase assays and mitochondrial experiments \u2014 2013 original paper<\/a><\/li>\n<\/ul>\n<p>\u062a\u0645 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0627\u0644\u0645\u0635\u0627\u062f\u0631 5 \u0623\u0643\u062a\u0648\u0628\u0631 2026. \u064a\u0633\u062a\u062e\u062f\u0645 \u0647\u0630\u0627 \u0627\u0644\u0634\u0631\u062d \u0627\u0644\u0645\u0644\u062e\u0635\u0627\u062a \u0627\u0644\u0623\u0635\u0644\u064a\u0629 \u0627\u0644\u0645\u062a\u0627\u062d\u0629 \u0648\u0623\u0648\u0635\u0627\u0641 \u0627\u0644\u0623\u0634\u0643\u0627\u0644. \u0627\u0644\u0631\u0633\u0645 \u0627\u0644\u0628\u064a\u0627\u0646\u064a \u0634\u0631\u062d \u0645\u0628\u0633\u0637 \u0648\u0644\u064a\u0633 \u0635\u0648\u0631\u0629 \u062a\u062c\u0631\u064a\u0628\u064a\u0629. \u0645\u0648\u0627\u062f \u0643\u062a\u0627\u0644\u0648\u062c NHD \u0645\u062e\u0635\u0635\u0629 \u0644\u0644\u0627\u0633\u062a\u0641\u0633\u0627\u0631\u0627\u062a \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0628\u062d\u062b \u0648\u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0648\u0627\u0644\u062a\u0635\u0646\u064a\u0639 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u064a \u0627\u0644\u0645\u0624\u0647\u0644\u060c \u0648\u0644\u064a\u0633 \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0628\u0634\u0631\u064a \u0623\u0648 \u0627\u0644\u0628\u064a\u0637\u0631\u064a.<\/p>","protected":false},"excerpt":{"rendered":"<p>\u064a\u064f\u062f\u0631\u0633 SS-31 \u0645\u0646 \u0623\u062c\u0644 \u062a\u0641\u0627\u0639\u0644\u0647 \u0645\u0639 \u062f\u0647\u0646 \u064a\u064f\u0633\u0645\u0649 \u0643\u0627\u0631\u062f\u064a\u0648\u0644\u064a\u0628\u064a\u0646 \u0641\u064a \u0627\u0644\u063a\u0634\u0627\u0621 \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a \u0627\u0644\u062f\u0627\u062e\u0644\u064a. \u064a\u0634\u0631\u062d \u0647\u0630\u0627 \u0627\u0644\u062f\u0644\u064a\u0644 \u062a\u0644\u0643 \u0627\u0644\u0639\u0644\u0627\u0642\u0629 \u0628\u0644\u063a\u0629 \u0645\u0628\u0633\u0637\u0629\u060c \u062b\u0645 \u064a\u0641\u0635\u0644 \u0628\u064a\u0646 \u0627\u0644\u0622\u0644\u064a\u0629 \u0627\u0644\u0645\u0642\u062a\u0631\u062d\u0629 \u0648\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0642\u0627\u0633\u0629 \u0641\u064a \u0643\u0644 \u062a\u062c\u0631\u0628\u0629.<\/p>","protected":false},"author":1,"featured_media":3947,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"364","pim_article_type":"Published study explanation","pim_evidence_level":"Mechanistic study with separate clinical context","pim_reviewer":"Codex AI editorial","pim_reviewed_date":"2026-10-09","pim_editorial_note":"AI-assisted editorial review; not independent human peer review. Experimental endpoints and catalogue material are distinguished.","pim_review_status":"reviewed","pim_review_reason":"Readability, endpoint definitions, existing-source preservation, related product and quote-link checks.","pim_creation_method":"AI-assisted writing; deterministic explanatory diagram.","pim_sources":"[]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-3535","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>SS-31 and Cardiolipin: The Mitochondrial Mechanism<\/title>\n<meta name=\"description\" content=\"SS-31 is studied for its interaction with a lipid called cardiolipin in the inner mitochondrial membrane. 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