{"id":756,"date":"2026-09-01T16:45:45","date_gmt":"2026-09-01T16:45:45","guid":{"rendered":"https:\/\/nhdbio.com\/resources\/pt-141-bremelanotide-free-base-acetate-finished-drug-boundary\/"},"modified":"2026-10-01T14:52:36","modified_gmt":"2026-10-01T14:52:36","slug":"%d8%a7%d9%84%d8%ac%d8%b2%d8%a1-141-%d8%a7%d9%84%d8%ad%d8%af-%d8%a7%d9%84%d8%a3%d9%82%d8%b5%d9%89-%d9%84%d9%85%d8%b3%d8%aa%d9%88%d9%89-%d8%b9%d9%82%d8%a7%d8%b1-%d8%a8%d8%b1%d9%8a%d9%85%d9%8a","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ar\/pt-141-bremelanotide-free-base-acetate-finished-drug-boundary\/","title":{"rendered":"PT-141\/\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f: \u0642\u0627\u0639\u062f\u0629 \u062d\u0631\u0629\u060c \u0623\u0633\u064a\u062a\u0627\u062a \u0648\u062d\u062f\u0648\u062f \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u0629"},"content":{"rendered":"

PT-141 \u0647\u0648 \u0631\u0645\u0632 \u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f. \u064a\u0639\u062a\u0628\u0631 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0630\u0648 \u0627\u0644\u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u062d\u0631\u0629 \u0648\u0634\u0643\u0644\u0647 \u0627\u0644\u0623\u0633\u064a\u062a\u0627\u062a\u064a \u0648\u0627\u0644\u062d\u0642\u0646 \u0627\u0644\u0646\u0647\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u0628\u0645\u062b\u0627\u0628\u0629 \u0633\u062c\u0644\u0627\u062a \u0630\u0627\u062a \u0635\u0644\u0629\u060c \u0648\u0644\u0643\u0646\u0647\u0627 \u0644\u064a\u0633\u062a \u0645\u0648\u0627\u062f \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u0628\u062f\u064a\u0644.<\/p>

\u0627\u0644\u0623\u062f\u0644\u0629 \u0641\u064a \u0644\u0645\u062d\u0629<\/h2>
  • \u064a\u0633\u0631\u062f PubChem \u0642\u0627\u0639\u062f\u0629 \u062e\u0627\u0644\u064a\u0629 \u0645\u0646 \u0627\u0644\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f \u0643\u0628\u0628\u062a\u064a\u062f \u062f\u0648\u0631\u064a \u0645\u0643\u0648\u0646 \u0645\u0646 \u0633\u0628\u0639\u0629 \u0628\u0642\u0627\u064a\u0627 \u0628\u0648\u0632\u0646 \u062c\u0632\u064a\u0626\u064a 1025.2 g\/mol.<\/li>
  • \u064a\u062f\u0631\u062c \u0645\u0648\u0642\u0639 DailyMed \u0623\u0633\u064a\u062a\u0627\u062a \u0627\u0644\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f \u0643\u0639\u0646\u0635\u0631 \u064a\u0642\u062f\u0645 1.75 \u0645\u0644\u063a \u0645\u0646 \u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f \u0641\u064a 0.3 \u0645\u0644\u064a\u0644\u062a\u0631 \u0645\u0646 \u0627\u0644\u0645\u0646\u062a\u062c \u0627\u0644\u0646\u0647\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u062a\u0645\u062f.<\/li>
  • \u062a\u0646\u0637\u0628\u0642 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a\u0629 \u0639\u0644\u0649 \u0627\u0644\u0635\u064a\u063a\u0629 \u0627\u0644\u0645\u062d\u062f\u062f\u0629 \u0648\u0627\u0644\u0634\u0631\u0643\u0629 \u0627\u0644\u0645\u0635\u0646\u0639\u0629 \u0648\u0648\u0636\u0639 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a - \u0648\u0644\u064a\u0633 \u0639\u0644\u0649 \u0643\u0644 \u0645\u0627\u062f\u0629 \u062a\u0633\u062a\u062e\u062f\u0645 PT-141 \u0643\u0645\u0631\u0627\u062f\u0641.<\/li><\/ul><\/div><\/div>
    \"\u0627\u0644\u062a\u0645\u064a\u064a\u0632
    \u0627\u0644\u062a\u0648\u0636\u064a\u062d \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a \u0627\u0644\u062a\u062d\u0631\u064a\u0631\u064a \u0627\u0644\u0623\u0635\u0644\u064a. \u0648\u0647\u064a \u0644\u0627 \u062a\u0635\u0648\u0631 \u0645\u0646\u062a\u062c\u064b\u0627 \u0645\u0632\u0648\u062f\u064b\u0627 \u0623\u0648 \u062f\u0641\u0639\u0629 \u062a\u0645 \u0625\u0635\u062f\u0627\u0631\u0647\u0627 \u0623\u0648 \u062a\u0631\u0643\u064a\u0628\u0629 \u0645\u0639\u062a\u0645\u062f\u0629 \u0623\u0648 \u0646\u062a\u064a\u062c\u0629 \u0627\u062e\u062a\u0628\u0627\u0631 \u0623\u0648 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0633\u0631\u064a\u0631\u064a.<\/figcaption><\/figure>

    \u0633\u062c\u0644 \u0627\u0644\u0647\u0648\u064a\u0629<\/h2>

    \u064a\u0634\u062a\u0645\u0644 \u0633\u062c\u0644 \u0627\u0644\u0628\u0628\u062a\u064a\u062f PubChem \u0639\u0644\u0649 \u062a\u0633\u0644\u0633\u0644 \u062f\u0648\u0631\u064a N-acetylated \u0645\u0639 \u0628\u0642\u0627\u064a\u0627 D-phenylalanine. \u062a\u0631\u062a\u064a\u0628 \u0627\u0644\u062a\u0633\u0644\u0633\u0644\u060c \u0648\u0627\u0644\u062f\u0648\u0631\u0627\u0646\u060c \u0648\u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u0645\u062c\u0633\u0645\u0629 \u0643\u0644\u0647\u0627 \u062a\u0633\u0627\u0647\u0645 \u0641\u064a \u0627\u0644\u0647\u0648\u064a\u0629\u061b \u0627\u0644\u0627\u0633\u0645 \u0627\u0644\u062a\u0633\u0648\u064a\u0642\u064a \u0627\u0644\u0642\u0635\u064a\u0631 \u0644\u0627 \u064a\u0644\u062a\u0642\u0637\u0647\u0645.<\/p>

    \u0643\u0648\u062f \u0627\u0644\u0628\u062d\u062b<\/strong>PT-141<\/span><\/div>
    \u0634\u0627\u0631\u062f\u0629 \u0646\u0634\u0637\u0629<\/strong>\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f. \u0628\u0648\u0628\u062a\u0634\u064a\u0645 CID 9941379<\/span><\/div>
    \u0627\u0644\u0645\u0643\u0648\u0646 \u0627\u0644\u062f\u0648\u0627\u0626\u064a \u0627\u0644\u0646\u0647\u0627\u0626\u064a<\/strong>\u062e\u0644\u0627\u062a \u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f<\/span><\/div>
    \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0627\u0644\u0647\u0648\u064a\u0629<\/strong>\u0627\u0644\u062a\u0633\u0644\u0633\u0644 \u0627\u0644\u062f\u0648\u0631\u064a\u060c \u0627\u0644\u0643\u064a\u0645\u064a\u0627\u0621 \u0627\u0644\u0645\u062c\u0633\u0645\u0629\u060c \u0627\u0644\u0623\u064a\u0648\u0646 \u0627\u0644\u0645\u0636\u0627\u062f\u060c \u0627\u0644\u0643\u062a\u0644\u0629\u060c \u0627\u0644\u0644\u0648\u0646\u064a\u060c \u0627\u0644\u0645\u062d\u062a\u0648\u0649 \u0648\u0631\u0628\u0637 \u0627\u0644\u062f\u0641\u0639\u0629<\/span><\/div><\/div><\/div>

    \u0627\u0644\u062d\u062f\u0648\u062f \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a\u0629 \u0648\u0627\u0644\u0623\u062f\u0644\u0629<\/h2>

    \u064a\u063a\u064a\u0631 \u0645\u062d\u062a\u0648\u0649 \u0627\u0644\u0623\u0633\u064a\u062a\u0627\u062a \u0648\u0632\u0646 \u0627\u0644\u0635\u064a\u063a\u0629 \u0648\u062d\u0633\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u062d\u062a\u0648\u0649. \u064a\u062c\u0628 \u0623\u0646 \u062a\u0648\u0636\u062d \u0627\u0644\u0634\u0647\u0627\u062f\u0629 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0642\u062f \u062a\u0645 \u0627\u0644\u0625\u0628\u0644\u0627\u063a \u0639\u0646\u0647\u0627 \u0639\u0644\u0649 \u0623\u0633\u0627\u0633 \u062d\u0631 \u0623\u0648 \u0623\u0633\u064a\u062a\u0627\u062a \u0623\u0648 \u0643\u0645\u0627 \u0647\u064a.<\/p>

    \u0644\u0627 \u062a\u0633\u062a\u0639\u064a\u0631 \u0623\u0628\u062f\u064b\u0627 \u0645\u0624\u0634\u0631 Vyleesi \u0623\u0648 \u0645\u0644\u0641 \u062a\u0639\u0631\u064a\u0641 \u0627\u0644\u0623\u0645\u0627\u0646 \u0643\u062f\u0644\u064a\u0644 \u0639\u0644\u0649 \u0623\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0643\u062a\u0627\u0644\u0648\u062c \u0645\u062a\u0643\u0627\u0641\u0626\u0629 \u0639\u0644\u0627\u062c\u064a\u064b\u0627. \u0627\u0644\u0627\u062a\u0635\u0627\u0644 \u0627\u0644\u0645\u0646\u0627\u0633\u0628 \u0647\u0648 \u0631\u0627\u0628\u0637 \u0633\u064a\u0627\u0642 \u0627\u0644\u0623\u062f\u0644\u0629 \u0645\u0639 \u062d\u062f\u0648\u062f \u0628\u0627\u0631\u0632\u0629 \u0644\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a.<\/p>

    \u0627\u0644\u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u062a\u062d\u0631\u064a\u0631\u064a\u0629<\/h2>

    \u0627\u0630\u0643\u0631 \u0627\u0644\u0645\u0627\u062f\u0629 \u0623\u0648 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0623\u0648 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0623\u0648 \u0627\u0644\u0633\u0643\u0627\u0646 \u0648\u0646\u0642\u0637\u0629 \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u062a\u064a \u064a\u062f\u0639\u0645\u0647\u0627 \u0627\u0644\u0633\u062c\u0644 \u0627\u0644\u0645\u0633\u062a\u0634\u0647\u062f \u0628\u0647 \u0639\u0644\u0649 \u0648\u062c\u0647 \u0627\u0644\u062a\u062d\u062f\u064a\u062f. \u0644\u0627 \u062a\u0642\u0645 \u0628\u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0645\u0639\u0642\u0648\u0644\u064a\u0629 \u0627\u0644\u0622\u0644\u064a\u0629\u060c \u0623\u0648 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629\u060c \u0623\u0648 \u0645\u0644\u0635\u0642 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u060c \u0623\u0648 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a \u0625\u0644\u0649 \u0645\u0637\u0627\u0644\u0628\u0629 \u0628\u0634\u0623\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0643\u062a\u0627\u0644\u0648\u062c \u063a\u064a\u0631 \u0630\u0627\u062a \u0635\u0644\u0629.<\/p>","protected":false},"excerpt":{"rendered":"

    PT-141 \u0647\u0648 \u0631\u0645\u0632 \u0627\u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0645\u0631\u062a\u0628\u0637 \u0628\u0627\u0644\u0628\u0631\u064a\u0645\u064a\u0644\u0627\u0646\u0648\u062a\u064a\u062f. \u064a\u0639\u062a\u0628\u0631 \u0627\u0644\u0628\u0628\u062a\u064a\u062f \u0630\u0648 \u0627\u0644\u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u062d\u0631\u0629 \u0648\u0634\u0643\u0644\u0647 \u0627\u0644\u0623\u0633\u064a\u062a\u0627\u062a\u064a \u0648\u0627\u0644\u062d\u0642\u0646 \u0627\u0644\u0646\u0647\u0627\u0626\u064a \u0627\u0644\u0645\u0639\u062a\u0645\u062f \u0628\u0645\u062b\u0627\u0628\u0629 \u0633\u062c\u0644\u0627\u062a \u0630\u0627\u062a \u0635\u0644\u0629\u060c \u0648\u0644\u0643\u0646\u0647\u0627 \u0644\u064a\u0633\u062a \u0645\u0648\u0627\u062f \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u062a\u0628\u062f\u064a\u0644.<\/p>","protected":false},"author":1,"featured_media":4014,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"358","pim_article_type":"Evidence and material-quality guide","pim_evidence_level":"FDA label plus curated chemical and peptide identity records","pim_reviewer":"Site evidence editorial team","pim_reviewed_date":"2026-09-02","pim_editorial_note":"Source-checked on 2026-09-02. Null results, study size, model\/population limits and relevant conflicts are retained. This is not medical advice, a customer case or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"Primary\/regulatory sources, factual claims, numerical results, limitations and product-evidence boundary checked for batch 3.","pim_creation_method":"The editorial workflow began with linked PubMed primary papers, systematic reviews, PubChem identity records and FDA\/DailyMed regulatory records. Population or model, denominators, endpoints, numerical results, null findings, limitations and conflicts were extracted before drafting. AI-assisted drafting and original image generation were used; the final facts and evidence boundaries were checked against the linked records on 2026-09-02. This is not independent peer review.","pim_sources":"[{\"title\":\"RECONNECT bremelanotide phase 3 trials\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31599840\/\",\"note\":\"Primary phase 3 publication; PMID 31599840.\"},{\"title\":\"DailyMed Vyleesi prescribing information\",\"url\":\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf\",\"note\":\"Current FDA-approved finished-drug label.\"},{\"title\":\"PubChem Bremelanotide record\",\"url\":\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Bremelanotide\",\"note\":\"Free-base peptide identity; CID 9941379.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-756","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"\nPT-141\/Bremelanotide: Free Base, Acetate and Finished-Drug Boundary<\/title>\n<meta name=\"description\" content=\"PT-141 is the development code associated with bremelanotide. 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