{"id":788,"date":"2026-09-01T17:35:05","date_gmt":"2026-09-01T17:35:05","guid":{"rendered":"https:\/\/nhdbio.com\/resources\/sermorelin-ghrh-1-29-amide-identity-lcms-guide\/"},"modified":"2026-09-08T07:30:41","modified_gmt":"2026-09-08T07:30:41","slug":"sermorelin-ghrh-1-29-amide-identity-lcms-guide","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ar\/sermorelin-ghrh-1-29-amide-identity-lcms-guide\/","title":{"rendered":"\u062f\u0644\u064a\u0644 \u0647\u0648\u064a\u0629 Sermorelin: GHRH(1\u201329)-Amide \u0648LC-MS"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">Sermorelin \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0628\u0628\u062a\u064a\u062f \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0644\u0628\u0642\u0627\u064a\u0627 29 \u064a\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u0645\u0646\u0637\u0642\u0629 N-terminal \u0627\u0644\u0646\u0634\u0637\u0629 \u0644\u0640 GHRH \u0627\u0644\u0628\u0634\u0631\u064a. \u0623\u0645\u064a\u062f \u0627\u0644\u0637\u0631\u0641 C \u0647\u0648 \u0627\u0644\u0630\u064a \u064a\u062d\u062f\u062f \u0627\u0644\u0647\u0648\u064a\u0629.<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">\u0627\u0644\u0623\u062f\u0644\u0629 \u0641\u064a \u0644\u0645\u062d\u0629<\/h2><ul class=\"wp-block-list\"><li>\u064a\u0633\u0631\u062f PubChem \u0627\u0644\u0635\u064a\u063a\u0629 C149H246N44O42S \u0648\u0627\u0644\u0648\u0632\u0646 \u0627\u0644\u062c\u0632\u064a\u0626\u064a 3357.9 g\/mol \u0644\u0640 Sermorelin.<\/li><li>\u0627\u0644\u062a\u0633\u0644\u0633\u0644 \u0647\u0648 YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2.<\/li><li>\u0623\u0628\u0644\u063a\u062a \u0637\u0631\u064a\u0642\u0629 LC-HRMS\/MS \u0644\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u062a\u064a \u062a\u0645 \u0627\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u062d\u062a\u0647\u0627 \u0639\u0646 \u062d\u062f\u0648\u062f \u0623\u0642\u0644 \u0644\u0644\u0643\u0634\u0641 \u0623\u0642\u0644 \u0645\u0646 50 pg \/ mL \u0645\u0639 \u0627\u0633\u062a\u0631\u062f\u0627\u062f 19 \u2013 37% \u0648\u0639\u062f\u0645 \u0627\u0644\u062f\u0642\u0629 \u0623\u0642\u0644 \u0645\u0646 20%.<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1672\" height=\"941\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality.webp\" alt=\"\u0645\u0634\u0647\u062f \u0627\u0644\u0645\u0646\u0634\u0623\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0627\u0644\u0648\u062b\u0627\u0626\u0642\u064a LC-MS\" class=\"wp-image-772\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality.webp 1672w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality-300x169.webp 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality-1024x576.webp 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality-768x432.webp 768w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/sermorelin-quality-1536x864.webp 1536w\" sizes=\"auto, (max-width: 1672px) 100vw, 1672px\" \/><figcaption class=\"wp-element-caption\">\u0631\u0633\u0645 \u062a\u0648\u0636\u064a\u062d\u064a \u062a\u062d\u0631\u064a\u0631\u064a \u062a\u0645 \u0625\u0646\u0634\u0627\u0624\u0647 \u0628\u0648\u0627\u0633\u0637\u0629 AI \u064a\u0648\u0636\u062d \u0633\u064a\u0631 \u0627\u0644\u0639\u0645\u0644 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a. \u0648\u0647\u064a \u0644\u0627 \u062a\u0635\u0648\u0631 \u0645\u0646\u062a\u062c\u064b\u0627 \u0645\u0632\u0648\u062f\u064b\u0627 \u0623\u0648 \u062f\u0641\u0639\u0629 \u062a\u0645 \u0625\u0635\u062f\u0627\u0631\u0647\u0627 \u0623\u0648 \u062a\u0631\u0643\u064a\u0628\u0629 \u0645\u0639\u062a\u0645\u062f\u0629 \u0623\u0648 \u0646\u062a\u064a\u062c\u0629 \u0627\u062e\u062a\u0628\u0627\u0631.<\/figcaption><\/figure><h2 class=\"wp-block-heading\">\u0633\u062c\u0644 \u0627\u0644\u0647\u0648\u064a\u0629<\/h2><p class=\"wp-block-paragraph\">\u062a\u062d\u062a\u0627\u062c \u062e\u0644\u0627\u062a Sermorelin \u0648\u062e\u0644\u0627\u062a Sermorelin \u0630\u0627\u062a \u0627\u0644\u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u062d\u0631\u0629 \u0625\u0644\u0649 \u0645\u062d\u0627\u0633\u0628\u0629 \u0645\u0646\u0641\u0635\u0644\u0629 \u0644\u0644\u0643\u062a\u0644\u0629 \u0648\u0627\u0644\u0645\u062d\u062a\u0648\u0649. \u064a\u062c\u0628 \u0623\u0646 \u064a\u0648\u0636\u062d \u0627\u0644\u0645\u0644\u0635\u0642 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646\u062a \u0643\u0645\u064a\u0629 \u0627\u0644\u0643\u062a\u0627\u0644\u0648\u062c \u062a\u0634\u064a\u0631 \u0625\u0644\u0649 \u0625\u062c\u0645\u0627\u0644\u064a \u0627\u0644\u0645\u0627\u062f\u0629 \u0623\u0648 \u0645\u0627 \u064a\u0639\u0627\u062f\u0644\u0647\u0627 \u0645\u0646 \u0627\u0644\u0628\u0628\u062a\u064a\u062f.<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>\u0637\u0648\u0644<\/strong><span>\u0627\u0644\u0623\u062d\u0645\u0627\u0636 \u0627\u0644\u0623\u0645\u064a\u0646\u064a\u0629 29<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u0634\u0643\u0644 \u0627\u0644\u0645\u062d\u0637\u0629<\/strong><span>\u0623\u0645\u064a\u062f \u0627\u0644\u0637\u0631\u0641 C<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u0627\u0644\u0635\u064a\u063a\u0629 \u0648\u0627\u0644\u0643\u062a\u0644\u0629<\/strong><span>C149H246N44O42S; 3357.9 \u062c\u0645\/\u0645\u0648\u0644<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u0628\u0648\u0628\u062a\u0634\u064a\u0645<\/strong><span>CID 16132413<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u0637\u0631\u064a\u0642\u0629 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629<\/strong><span>\u062a\u0646\u0642\u064a\u0629 \u0627\u0644\u0623\u0644\u0641\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0646\u0627\u0646\u0648 UHPLC-HRMS\/MS<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">\u0627\u0644\u062d\u062f\u0648\u062f \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a\u0629 \u0648\u0627\u0644\u0623\u062f\u0644\u0629<\/h2><p class=\"wp-block-paragraph\">\u0623\u0638\u0647\u0631\u062a \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 2016 \u0627\u0644\u0627\u0633\u062a\u0631\u062f\u0627\u062f \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a \u0645\u0646 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0627\u0644\u0628\u0634\u0631\u064a\u0629 \u0627\u0644\u0645\u062d\u0635\u0646\u0629 \u0644\u0640 Sermorelin \u0648\u0646\u0638\u0627\u0626\u0631\u0647\u0627 GHRH \u0630\u0627\u062a \u0627\u0644\u0635\u0644\u0629. \u0644\u0642\u062f \u0643\u0627\u0646\u062a \u062f\u0631\u0627\u0633\u0629 \u0644\u0644\u062a\u062d\u0642\u0642 \u0645\u0646 \u0635\u062d\u0629 \u0637\u0631\u064a\u0642\u0629 \u0645\u0643\u0627\u0641\u062d\u0629 \u0627\u0644\u0645\u0646\u0634\u0637\u0627\u062a\u060c \u0648\u0644\u064a\u0633\u062a \u062f\u0631\u0627\u0633\u0629 \u0644\u0644\u0641\u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0639\u0644\u0627\u062c\u064a\u0629.<\/p><p class=\"wp-block-paragraph\">\u064a\u062c\u0628 \u0623\u0646 \u064a\u062c\u0645\u0639 \u0633\u062c\u0644 \u0627\u0644\u062f\u0641\u0639\u0629 \u0627\u0644\u0643\u0627\u0645\u0644 \u0628\u064a\u0646 \u0627\u0644\u062a\u0633\u0644\u0633\u0644 \u0623\u0648 \u0627\u0644\u0643\u062a\u0644\u0629 \u0627\u0644\u0633\u0644\u064a\u0645\u0629 \u0630\u0627\u062a \u0627\u0644\u062f\u0642\u0629 \u0627\u0644\u0639\u0627\u0644\u064a\u0629\u060c \u0648\u0627\u0644\u0643\u0631\u0648\u0645\u0627\u062a\u0648\u063a\u0631\u0627\u0641\u064a\u0627\u060c \u0648\u0623\u0633\u0627\u0633 \u0627\u0644\u0645\u062d\u062a\u0648\u0649\u060c \u0648\u0627\u0644\u0645\u0639\u0644\u0648\u0645\u0627\u062a \u0627\u0644\u0645\u062a\u0639\u0644\u0642\u0629 \u0628\u0627\u0644\u0645\u064a\u0627\u0647 \u0648\u0627\u0644\u0623\u0636\u062f\u0627\u062f. \u0644\u0627 \u064a\u062d\u0644 \u062d\u062f \u0627\u0643\u062a\u0634\u0627\u0641 \u0627\u0644\u0628\u0644\u0627\u0632\u0645\u0627 \u0645\u062d\u0644 \u0645\u0648\u0627\u0635\u0641\u0627\u062a \u0625\u0635\u062f\u0627\u0631 \u0627\u0644\u0645\u0646\u062a\u062c.<\/p><h2 class=\"wp-block-heading\">\u0627\u0644\u0642\u0627\u0639\u062f\u0629 \u0627\u0644\u062a\u062d\u0631\u064a\u0631\u064a\u0629<\/h2><p class=\"wp-block-paragraph\">\u0627\u0630\u0643\u0631 \u0627\u0644\u0645\u0627\u062f\u0629 \u0623\u0648 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0623\u0648 \u0627\u0644\u0646\u0645\u0648\u0630\u062c \u0623\u0648 \u0627\u0644\u0633\u0643\u0627\u0646 \u0648\u0646\u0642\u0637\u0629 \u0627\u0644\u0646\u0647\u0627\u064a\u0629 \u0627\u0644\u062a\u064a \u064a\u062f\u0639\u0645\u0647\u0627 \u0627\u0644\u0633\u062c\u0644 \u0627\u0644\u0645\u0633\u062a\u0634\u0647\u062f \u0628\u0647 \u0639\u0644\u0649 \u0648\u062c\u0647 \u0627\u0644\u062a\u062d\u062f\u064a\u062f. \u0644\u0627 \u062a\u0642\u0645 \u0628\u062a\u062d\u0648\u064a\u0644 \u0627\u0644\u0645\u0639\u0642\u0648\u0644\u064a\u0629 \u0627\u0644\u0622\u0644\u064a\u0629\u060c \u0623\u0648 \u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u062d\u064a\u0648\u0627\u0646\u064a\u0629\u060c \u0623\u0648 \u0627\u0644\u0645\u0644\u0635\u0642 \u0627\u0644\u0631\u0633\u0645\u064a \u0644\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0646\u0647\u0627\u0626\u064a\u060c \u0623\u0648 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631 \u0627\u0644\u062a\u062d\u0644\u064a\u0644\u064a \u0625\u0644\u0649 \u0627\u062f\u0639\u0627\u0621 \u0628\u0634\u0623\u0646 \u0645\u062c\u0645\u0648\u0639\u0629 \u0643\u062a\u0627\u0644\u0648\u062c \u063a\u064a\u0631 \u0630\u0627\u062a \u0635\u0644\u0629.<\/p>","protected":false},"excerpt":{"rendered":"<p>Sermorelin \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0628\u0628\u062a\u064a\u062f \u0645\u062a\u0648\u0633\u0637 \u200b\u200b\u0644\u0628\u0642\u0627\u064a\u0627 29 \u064a\u062a\u0648\u0627\u0641\u0642 \u0645\u0639 \u0645\u0646\u0637\u0642\u0629 N-terminal \u0627\u0644\u0646\u0634\u0637\u0629 \u0644\u0640 GHRH \u0627\u0644\u0628\u0634\u0631\u064a. \u0623\u0645\u064a\u062f \u0627\u0644\u0637\u0631\u0641 C \u0647\u0648 \u0627\u0644\u0630\u064a \u064a\u062d\u062f\u062f \u0627\u0644\u0647\u0648\u064a\u0629.<\/p>","protected":false},"author":1,"featured_media":772,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"362","pim_article_type":"Evidence and material-quality guide","pim_evidence_level":"PubChem sequence identity plus validated human-plasma detection literature","pim_reviewer":"Site evidence editorial team","pim_reviewed_date":"2026-09-02","pim_editorial_note":"Source-checked on 2026-09-02. Null results, sample size, model\/population limits and regulatory scope are retained. This is not medical advice, a customer case or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"Primary and official sources, numerical results, null findings, limitations, product-evidence boundary and image disclosure checked for batch 4.","pim_creation_method":"This article discusses the source records listed below, with the study models and limitations stated alongside the findings. AI-assisted drafting and image generation were used. The reference list identifies the records behind this article; it is not an independent peer review or verification of a supplied catalog lot.","pim_sources":"[{\"title\":\"GRF1-29 stimulation in normal subjects\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6240568\/\",\"note\":\"Primary human physiology study; PMID 6240568.\"},{\"title\":\"Low-dose GHRH(1\u201329)-amide dose-response study\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7921207\/\",\"note\":\"Primary human dose-response study; PMID 7921207.\"},{\"title\":\"Sermorelin pediatric review\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18031173\/\",\"note\":\"Historical diagnostic and pediatric treatment review; PMID 18031173.\"},{\"title\":\"GHRH analog detection in human plasma\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26879649\/\",\"note\":\"Validated LC-HRMS\/MS method; PMID 26879649.\"},{\"title\":\"PubChem Sermorelin record\",\"url\":\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Sermorelin\",\"note\":\"Sequence, formula and molecular weight; CID 16132413.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-788","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Sermorelin Identity Guide: GHRH(1\u201329)-Amide and LC-MS<\/title>\n<meta name=\"description\" content=\"Sermorelin is an amidated 29-residue peptide corresponding to the active N-terminal region of human GHRH. 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