{"id":3117,"date":"2026-10-04T13:31:46","date_gmt":"2026-10-04T13:31:46","guid":{"rendered":"https:\/\/nhdbio.com\/?p=3117"},"modified":"2026-10-04T15:11:54","modified_gmt":"2026-10-04T15:11:54","slug":"%e9%87%8d%e8%82%bd%e5%90%8c%e4%bd%8d%e7%b4%a0%e5%af%8c%e9%9b%86%e5%8c%96%e5%ad%a6%e7%ba%af%e5%ba%a6%e5%b7%ae%e5%bc%82","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\/","title":{"rendered":"\u91cd\u80bd\uff1a99% \u540c\u4f4d\u7d20\u5bcc\u96c6\u4e0d\u7b49\u4e8e 99% \u5316\u5b66\u7eaf\u5ea6"},"content":{"rendered":"<p>\u91cd\u80bd\u89c4\u683c\u53ef\u80fd\u5305\u542b\u591a\u4e2a\u767e\u5206\u6bd4\u3002\u5b83\u4eec\u770b\u8d77\u6765\u53ef\u4ee5\u4e92\u6362\uff0c\u4f46\u56de\u7b54\u7684\u662f\u4e0d\u540c\u95ee\u9898\u3002\u540c\u4f4d\u7d20\u5bcc\u96c6\u5ea6\u63cf\u8ff0\u7684\u662f\u6807\u8bb0\u539f\u5b50\uff1b\u5316\u5b66\u7eaf\u5ea6\u63cf\u8ff0\u7684\u662f\u5728\u6307\u5b9a\u5206\u6790\u65b9\u6cd5\u4e0b\u6750\u6599\u7684\u7ec4\u6210\u3002<\/p>\n<h2>\u4e00\u4e2a\u771f\u5b9e\u76ee\u5f55\u793a\u4f8b\u5c55\u793a\u4e86\u8fd9\u79cd\u533a\u522b<\/h2>\n<p>Sigma-Aldrich \u7684 L-\u8d56\u6c28\u9178-13C6,15N2 \u76d0\u9178\u76d0\u6761\u76ee\u5206\u522b\u5217\u51fa 99 atom % \u7684\u78b3-13\u300199 atom % \u7684\u6c2e-15\uff0c\u4ee5\u53ca 95% 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href=\"https:\/\/nhdbio.com\/cn\/%e5%bc%95%e7%94%a8\/\">\u5c06\u60a8\u7684\u5e8f\u5217\u6216\u4ea7\u54c1\u540d\u79f0\u3001\u6570\u91cf\u53ca\u6240\u9700\u6587\u4ef6\u53d1\u9001\u81f3 NHD<\/a>\u3002\u4e0b\u5355\u524d\u8bf7\u786e\u8ba4\u5177\u4f53\u5f62\u5f0f\u3001\u53ef\u884c\u6027\u3001\u53ef\u63d0\u4f9b\u7684\u68c0\u6d4b\u53ca\u4ea4\u4ed8\u6761\u6b3e\u3002<\/p>\n<h2>\u6765\u6e90<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.sigmaaldrich.com\/US\/en\/product\/aldrich\/608041\">Sigma-Aldrich\uff1a\u5bcc\u96c6\u4e0e\u6d4b\u5b9a\u5b57\u6bb5\u5206\u5f00<\/a><\/li>\n<li><a href=\"https:\/\/www.jpt.com\/products-services\/peptide-modifications\/isotope-labeled-peptides\/\">JPT\uff1a\u540c\u4f4d\u7d20\u6807\u8bb0\u80bd<\/a><\/li>\n<\/ul>\n<p>\u516c\u5f00\u53c2\u8003\u6587\u732e\u89e3\u91ca\u4e86\u8be5\u4e3b\u9898\uff1b\u5b83\u4eec\u4e0d\u662f NHD 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calculations","pim_reviewer":"Codex AI editorial","pim_reviewed_date":"2026-10-04","pim_editorial_note":"Public data and labeled teaching calculations; not NHD batch results. Confirm project and document availability.","pim_review_status":"reviewed","pim_review_reason":"Source, arithmetic, identity and search-intent checks. No independent human technical review recorded.","pim_creation_method":"AI-assisted writing, source checks and illustrated cover.","pim_sources":"[{\"title\":\"Sigma-Aldrich: separate enrichment and assay fields\",\"url\":\"https:\/\/www.sigmaaldrich.com\/US\/en\/product\/aldrich\/608041\",\"note\":\"Public reference, not NHD batch evidence.\"},{\"title\":\"JPT: isotope-labelled peptides\",\"url\":\"https:\/\/www.jpt.com\/products-services\/peptide-modifications\/isotope-labeled-peptides\/\",\"note\":\"Public reference, not NHD batch evidence.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-3117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Heavy peptides: 99% isotope enrichment is not 99% chemical purity - NHD<\/title>\n<meta name=\"description\" content=\"Peptide Raw Materials and Custom Peptide Synthesis\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/cn\/\u91cd\u80bd\u540c\u4f4d\u7d20\u5bcc\u96c6\u5316\u5b66\u7eaf\u5ea6\u5dee\u5f02\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Heavy peptides: 99% isotope enrichment is not 99% chemical purity\" \/>\n<meta property=\"og:description\" content=\"A heavy peptide specification may contain several percentages. They can look interchangeable, but they answer different questions. Isotope enrichment describes the labelled atoms; chemical purity describes the composition of the material under a stated analytical method.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nhdbio.com\/cn\/\u91cd\u80bd\u540c\u4f4d\u7d20\u5bcc\u96c6\u5316\u5b66\u7eaf\u5ea6\u5dee\u5f02\/\" \/>\n<meta property=\"og:site_name\" content=\"NHD\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-04T13:31:46+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-04T15:11:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/isotope-purity-cover.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1536\" \/>\n\t<meta property=\"og:image:height\" content=\"1024\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"NHD Technical Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:description\" content=\"Peptide Raw Materials and Custom Peptide Synthesis\" \/>\n<meta name=\"twitter:label1\" content=\"\u4f5c\u8005\" \/>\n\t<meta name=\"twitter:data1\" content=\"NHD Technical Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u9884\u8ba1\u9605\u8bfb\u65f6\u95f4\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 \u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\\\/\"},\"author\":{\"name\":\"NHD Technical Team\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#\\\/schema\\\/person\\\/0ffb0dec7fda0f720073fc468fac6fc1\"},\"headline\":\"Heavy peptides: 99% isotope enrichment is not 99% chemical purity\",\"datePublished\":\"2026-10-04T13:31:46+00:00\",\"dateModified\":\"2026-10-04T15:11:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\\\/\"},\"wordCount\":385,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/10\\\/isotope-purity-cover.png\",\"articleSection\":[\"Evidence &amp; 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