{"id":4277,"date":"2026-10-12T08:32:31","date_gmt":"2026-10-12T08:32:31","guid":{"rendered":"https:\/\/nhdbio.com\/?p=4277"},"modified":"2026-10-12T08:32:31","modified_gmt":"2026-10-12T08:32:31","slug":"cagrisema-%e5%99%a8%e5%ae%98%e8%84%82%e8%82%aa%e9%aa%a8%e6%a0%87%e5%bf%97%e7%89%a9%e8%a7%a3%e9%87%8a","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/cagrisema-organ-fat-bone-markers-explained\/","title":{"rendered":"CagriSema\u51cf\u91cd\u4ee5\u540e\uff0c\u809d\u810f\u8102\u80aa\u548c\u9aa8\u9abc\u4e5f\u53d8\u4e86\u5417\uff1f"},"content":{"rendered":"<div class=\"notranslate\" data-no-translation lang=\"zh-CN\"><div class=\"nhd-news-lesson\"><figure class=\"cover\"><img src=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/nhd-news-20261012-05.webp\" alt=\"\u7814\u7a76\u4eba\u5458\u89c2\u5bdf\u809d\u810f\u3001\u80f0\u817a\u548c\u9aa8\u9abc\u6a21\u578b\u7684\u4e3b\u9898\u63d2\u753b\" width=\"1672\" height=\"941\"><figcaption>\u4e3b\u9898\u7f16\u8f91\u63d2\u753b\uff0c\u975e\u5b9e\u9a8c\u7167\u7247\u3002<\/figcaption><\/figure><p class=\"lead\">\u4f53\u91cd\u79e4\u663e\u793a\u5c11\u4e86\u5341\u51e0\u516c\u65a4\uff0c\u5374\u6ca1\u544a\u8bc9\u6211\u4eec\u5c11\u6389\u7684\u662f\u54ea\u4e00\u90e8\u5206\u30029\u670830\u65e5\u516c\u5e03\u7684CagriSema\u6570\u636e\uff0c\u5206\u522b\u770b\u4e86\u5668\u5b98\u8102\u80aa\u548c\u9aa8\u9abc\u66f4\u65b0\u6307\u6807\u3002\u8fd9\u4e24\u90e8\u5206\u6765\u81ea\u4e0d\u540c\u7814\u7a76\uff0c\u9700\u8981\u5206\u5f00\u8bfb\u3002<\/p><section class=\"section\" id=\"section-1\"><h2>CagriSema\u4e3a\u4ec0\u4e48\u6709\u4e24\u4e2a\u540d\u5b57\uff1f<\/h2><p>\u5b83\u662fcagrilintide\u4e0esemaglutide\u7684\u56fa\u5b9a\u7ec4\u5408\uff1a\u524d\u8005\u4f5c\u7528\u4e8e\u80f0\u6dc0\u7d20\u76f8\u5173\u53d7\u4f53\uff0c\u540e\u8005\u4f5c\u7528\u4e8eGLP-1\u53d7\u4f53\u3002\u7814\u7a76\u8005\u5e0c\u671b\u901a\u8fc7\u4e0d\u540c\u4fe1\u53f7\u5171\u540c\u5f71\u54cd\u98df\u6b32\u548c\u4ee3\u8c22\u3002<\/p><p>\u7ec4\u5408\u836f\u7684\u7ed3\u679c\u5c5e\u4e8e\u7ec4\u5408\u5236\u5242\u3002\u4e0d\u80fd\u628a\u6240\u6709\u53d8\u5316\u90fd\u7b97\u5728cagrilintide\u4e00\u4e2a\u6210\u5206\u8eab\u4e0a\uff0c\u4e5f\u4e0d\u80fd\u8ba4\u4e3a\u4efb\u610f\u6bd4\u4f8b\u6df7\u5408\u4e24\u79cd\u7814\u7a76\u539f\u6599\u5c31\u80fd\u590d\u5236\u4e34\u5e8a\u7ed3\u679c\u3002<\/p><\/section><section class=\"section\" id=\"section-2\"><h2>\u5668\u5b98\u8102\u80aa\u90e8\u5206\uff0c\u6765\u81eaREIMAGINE 1<\/h2><p>\u516c\u544a\u4ecb\u7ecd\u4e86\u65e9\u671f2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u4e00\u9879\u78c1\u5171\u632f\u5b50\u7814\u7a76\u3002\u7814\u7a76\u770b\u5230\u8179\u90e8\u4ee5\u53ca\u809d\u810f\u3001\u80f0\u817a\u76f8\u5173\u8102\u80aa\u51cf\u5c11\uff0c\u5e76\u62a5\u544a\u7ec4\u5408\u6cbb\u7597\u5728\u7b2c40\u5468\u4f53\u91cd\u4e0b\u964d14.3%\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u8fd9\u4e9b\u68c0\u67e5\u5173\u6ce8\u7684\u662f\u8102\u80aa\u50a8\u5b58\u7684\u4f4d\u7f6e\u3002\u8179\u90e8\u8102\u80aa\u548c\u5668\u5b98\u5185\u8102\u80aa\u6709\u5404\u81ea\u7684\u6d4b\u91cf\u65b9\u5f0f\uff0c\u4e0d\u80fd\u56e0\u4e3a\u8170\u56f4\u53d8\u5c0f\uff0c\u5c31\u8ba4\u5b9a\u80f0\u817a\u4e2d\u7684\u8102\u80aa\u4e5f\u6309\u540c\u6837\u6bd4\u4f8b\u4e0b\u964d\u3002<\/p><\/section><section class=\"section\" id=\"section-3\"><h2>\u9aa8\u9abc\u90e8\u5206\uff0c\u6765\u81ea\u53e6\u4e00\u9879\u8bd5\u9a8c<\/h2><p>REIMAGINE 2\u7684\u4e8b\u540e\u5206\u6790\u770b\u4e86\u9aa8\u4ee3\u8c22\u6807\u5fd7\u7269\uff0c\u5373\u53cd\u6620\u9aa8\u7ec4\u7ec7\u5f62\u6210\u3001\u5206\u89e3\u6d3b\u52a8\u7684\u6307\u6807\u3002\u516c\u544a\u62a5\u544a\uff0c\u7b2c68\u5468\u4f53\u91cd\u4e0b\u964d14.2%\u7684\u540c\u65f6\uff0c\u76f8\u5173\u6307\u6807\u63d0\u4f9b\u4e86\u521d\u6b65\u7684\u5b89\u5fc3\u4fe1\u53f7\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>14.3%\u5bf9\u5e9440\u5468\u7684REIMAGINE 1\uff0c14.2%\u5bf9\u5e9468\u5468\u7684REIMAGINE 2\u3002\u5b83\u4eec\u770b\u8d77\u6765\u5f88\u63a5\u8fd1\uff0c\u4f46\u4e0d\u662f\u540c\u4e00\u6279\u4eba\u7684\u8fde\u7eed\u4e24\u6b21\u7ed3\u679c\u3002<\/p><aside class=\"helper\"><div class=\"helper-title\">\u4e24\u4efd\u6570\u636e\u6765\u81ea\u4e0d\u540c\u8bd5\u9a8c<\/div><div class=\"table-scroll\"><table class=\"data-table\"><thead><tr><th scope=\"col\">\u8bd5\u9a8c<\/th><th scope=\"col\">\u89c2\u5bdf\u91cd\u70b9<\/th><th scope=\"col\">\u62a5\u9053\u65f6\u95f4\u70b9<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">REIMAGINE 1<\/th><td>\u78c1\u5171\u632f\u4e0e\u5668\u5b98\u8102\u80aa<\/td><td>40\u5468<\/td><\/tr><tr><th scope=\"row\">REIMAGINE 2<\/th><td>\u9aa8\u4ee3\u8c22\u6807\u5fd7\u7269<\/td><td>68\u5468<\/td><\/tr><\/tbody><\/table><\/div><p class=\"helper-note\">\u6309\u539f\u59cb\u516c\u544a\u62c6\u5206\uff1b\u5e76\u975e\u540c\u4e00\u6279\u4eba\u7684\u8fde\u7eed\u68c0\u67e5\u3002<\/p><\/aside><\/section><section class=\"section\" id=\"section-4\"><h2>\u9aa8\u4ee3\u8c22\u6307\u6807\u597d\u770b\uff0c\u7b49\u4e8e\u9aa8\u5934\u66f4\u7ed3\u5b9e\u5417\uff1f<\/h2><p>\u8fd8\u4e0d\u80fd\u8fd9\u6837\u8bf4\u3002\u9aa8\u9abc\u4e00\u76f4\u5728\u66f4\u65b0\uff0c\u8840\u6db2\u4e2d\u7684\u6807\u5fd7\u7269\u80fd\u5e2e\u52a9\u89c2\u5bdf\u8fd9\u4e2a\u8fc7\u7a0b\uff0c\u5374\u4e0d\u80fd\u5355\u72ec\u4ee3\u66ff\u9aa8\u5bc6\u5ea6\u3001\u9aa8\u5f3a\u5ea6\u6216\u9aa8\u6298\u968f\u8bbf\u3002<\/p><p>\u5c31\u50cf\u770b\u5230\u65bd\u5de5\u961f\u5728\u6b63\u5e38\u5de5\u4f5c\uff0c\u4e0d\u7b49\u4e8e\u5df2\u7ecf\u6d4b\u8fc7\u623f\u5b50\u7684\u6297\u9707\u80fd\u529b\u3002\u82e5\u8981\u56de\u7b54\u957f\u671f\u9aa8\u9abc\u662f\u5426\u5f97\u5230\u4fdd\u62a4\uff0c\u8fd8\u9700\u8981\u76f8\u5e94\u7684\u76f4\u63a5\u6307\u6807\u548c\u66f4\u957f\u89c2\u5bdf\u3002<\/p><\/section><section class=\"section\" id=\"section-5\"><h2>\u8fd9\u6b21\u65b0\u95fb\u771f\u6b63\u8865\u5145\u4e86\u4ec0\u4e48\uff1f<\/h2><p>\u5b83\u628a\u95ee\u9898\u4ece\u201c\u51cf\u4e86\u591a\u5c11\u4f53\u91cd\u201d\u6269\u5c55\u5230\u201c\u8102\u80aa\u5728\u54ea\u91cc\u51cf\u5c11\u3001\u5176\u4ed6\u7ec4\u7ec7\u5982\u4f55\u53d8\u5316\u201d\u3002\u8fd9\u662f\u8bc4\u4ef7\u51cf\u91cd\u8d28\u91cf\u7684\u4e00\u79cd\u505a\u6cd5\u3002<\/p><p>\u4f46\u516c\u544a\u6ca1\u6709\u8be6\u7ec6\u516c\u5f00\u6bcf\u4e2a\u5668\u5b98\u8102\u80aa\u7684\u6570\u503c\uff0c\u4e5f\u6ca1\u6709\u7ed9\u51fa\u957f\u671f\u9aa8\u6298\u7ed3\u679c\u3002\u9605\u8bfb\u65f6\uff0c\u628a\u5df2\u7ecf\u6d4b\u5230\u7684\u53d8\u5316\u548c\u4ecd\u5f85\u56de\u7b54\u7684\u95ee\u9898\u5206\u5f00\uff0c\u624d\u4e0d\u4f1a\u5938\u5927\u8fd9\u6761\u65b0\u95fb\u3002<\/p><\/section><section class=\"section\" id=\"section-6\"><h2>\u8170\u56f4\u53d8\u5c0f\uff0c\u53ef\u4ee5\u4ee3\u66ff\u5668\u5b98\u8102\u80aa\u68c0\u67e5\u5417\uff1f<\/h2><p>\u8170\u56f4\u63d0\u4f9b\u8179\u90e8\u4f53\u578b\u4fe1\u606f\uff0c\u4f46\u4e0d\u80fd\u544a\u8bc9\u6211\u4eec\u809d\u810f\u6216\u80f0\u817a\u4e2d\u5177\u4f53\u542b\u6709\u591a\u5c11\u8102\u80aa\u3002\u4e24\u79cd\u6d4b\u91cf\u53ef\u4ee5\u4e92\u76f8\u8865\u5145\uff0c\u4e0d\u9002\u5408\u6309\u540c\u4e00\u4e2a\u767e\u5206\u6bd4\u6362\u7b97\u3002<\/p><p>\u82e5\u62a5\u9053\u540c\u65f6\u5217\u51fa\u8170\u56f4\u3001\u4f53\u91cd\u548c\u78c1\u5171\u632f\u7ed3\u679c\uff0c\u53ef\u4ee5\u5148\u5404\u753b\u4e00\u884c\u3002\u660e\u786e\u6bcf\u4e00\u884c\u7684\u8bd5\u9a8c\u540d\u79f0\u4e0e\u65f6\u95f4\u70b9\uff0c\u5c31\u4e0d\u5bb9\u6613\u628a\u4e0d\u540c\u68c0\u67e5\u6df7\u6210\u4e00\u4e2a\u7ed3\u679c\u3002<\/p><\/section><aside class=\"takeaway\"><strong>\u8bfb\u8fd9\u7bc7\u65f6\uff0c\u8bb0\u4f4f\u8fd9\u4e00\u70b9<\/strong><p>\u5668\u5b98\u8102\u80aa\u548c\u9aa8\u4ee3\u8c22\u6765\u81ea\u4e0d\u540c\u8bd5\u9a8c\uff1b\u9aa8\u4ee3\u8c22\u6807\u5fd7\u7269\u4e0d\u80fd\u5355\u72ec\u8bc1\u660e\u9aa8\u6298\u98ce\u9669\u964d\u4f4e\u3002<\/p><\/aside><section class=\"materials\" id=\"materials\"><div class=\"eyebrow\">\u76f8\u5173\u7814\u7a76\u6750\u6599<\/div><h2>\u67e5\u770b\u6750\u6599\u4e0e\u5206\u6790\u8d44\u6599<\/h2><p class=\"materials-intro\">\u53ef\u67e5\u770bcagrilintide\u7684\u76ee\u5f55\u8d44\u6599\uff0c\u4e86\u89e3\u80f0\u6dc0\u7d20\u76f8\u5173\u7814\u7a76\u6750\u6599\u3002\u4e34\u5e8a\u56fa\u5b9a\u7ec4\u5408\u7684\u5236\u5242\u3001\u5242\u91cf\u548c\u8d28\u91cf\u8981\u6c42\uff0c\u9700\u8981\u4e0e\u76ee\u5f55\u539f\u6599\u5206\u522b\u786e\u8ba4\u3002<\/p><div class=\"product-grid\"><article class=\"product-card\"><div class=\"card-head\"><div><div class=\"product-label\">\u80f0\u6dc0\u7d20\u76f8\u5173\u7814\u7a76<\/div><h3>\u5361\u683c\u5217\u80bd \u00b7 Cagrilintide<\/h3><\/div><\/div><div class=\"card-body\"><p>\u67e5\u770b\u5355\u4e00\u7814\u7a76\u6750\u6599\u7684\u89c4\u683c\uff0c\u53e6\u884c\u786e\u8ba4\u7ec4\u5408\u5236\u5242\u6761\u4ef6\u3002<\/p><a href=\"https:\/\/nhdbio.com\/cn\/%e4%ba%a7%e5%93%81\/%e5%8d%a1%e6%a0%bc%e6%9e%97%e8%83%b0%e5%b2%9b%e7%b4%a0\/\" target=\"_blank\" rel=\"noopener\">\u67e5\u770b\u4ea7\u54c1\u8d44\u6599 \u2192<\/a><\/div><\/article><\/div><\/section><section class=\"sources\" id=\"sources\"><h2>\u539f\u59cb\u8d44\u6599<\/h2><div>\u8d44\u6599\u65e5\u671f\uff1a2026-09-30 \u00b7 \u4eba\u4f53\u5b50\u7814\u7a76\uff0b\u4e8b\u540e\u9aa8\u4ee3\u8c22\u5206\u6790<\/div><ul><li><a href=\"https:\/\/www.novonordisk.com\/news-and-media\/news-and-ir-materials\/news-details.html?id=917138\" target=\"_blank\" rel=\"noopener\">\u539f\u59cb\u516c\u544a\uff0f\u7814\u7a76\u53d1\u5e03\u9875\u9762 \u2197<\/a><\/li><\/ul><\/section><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u4f53\u91cd\u79e4\u663e\u793a\u5c11\u4e86\u5341\u51e0\u516c\u65a4\uff0c\u5374\u6ca1\u544a\u8bc9\u6211\u4eec\u5c11\u6389\u7684\u662f\u54ea\u4e00\u90e8\u5206\u30029\u670830\u65e5\u516c\u5e03\u7684CagriSema\u6570\u636e\uff0c\u5206\u522b\u770b\u4e86\u5668\u5b98\u8102\u80aa\u548c\u9aa8\u9abc\u66f4\u65b0\u6307\u6807\u3002\u8fd9\u4e24\u90e8\u5206\u6765\u81ea\u4e0d\u540c\u7814\u7a76\uff0c\u9700\u8981\u5206\u5f00\u8bfb\u3002<\/p>","protected":false},"author":1,"featured_media":4276,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"320","pim_article_type":"Published research explained","pim_evidence_level":"Human substudy + post hoc bone metabolism analysis","pim_reviewer":"AI-assisted source and editorial check","pim_reviewed_date":"2026-10-12","pim_editorial_note":"Original public sources, study populations and limitations are linked. Editorial illustrations are not experimental photographs.","pim_review_status":"reviewed","pim_review_reason":"Reviewed Chinese source, protected scientific values and links, unique illustration, related product families and responsive layout checked.","pim_creation_method":"AI-assisted writing","pim_sources":"[{\"title\":\"Research news reference \u2014 www.novonordisk.com \u2014 news-05\",\"note\":\"\",\"url\":\"https:\/\/www.novonordisk.com\/news-and-media\/news-and-ir-materials\/news-details.html?id=917138\"}]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-4277","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CagriSema: what changed in organ fat and bone turnover? | NHD<\/title>\n<meta name=\"description\" content=\"The scale shows more than ten kilograms lost, but it does not tell us which part was lost. The CagriSema data announced on September 30 looked separately at organ fat and bone turnover markers. These two parts come from different studies and need to be read separately.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/cn\/cagrisema-\u5668\u5b98\u8102\u80aa\u9aa8\u6807\u5fd7\u7269\u89e3\u91ca\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"CagriSema: what changed in organ fat and bone turnover?\" \/>\n<meta property=\"og:description\" content=\"The scale shows more than ten kilograms lost, but it does not tell us which part was lost. The CagriSema data announced on September 30 looked separately at organ fat and bone turnover markers. 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