{"id":4284,"date":"2026-10-12T08:32:32","date_gmt":"2026-10-12T08:32:32","guid":{"rendered":"https:\/\/nhdbio.com\/?p=4284"},"modified":"2026-10-12T08:32:32","modified_gmt":"2026-10-12T08:32:32","slug":"cagrisema-%e9%87%8d%e6%96%b0%e5%ae%9a%e4%b9%899%e4%bd%8e%e5%89%82%e9%87%8f68%e5%91%a8","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/cagrisema-redefine9-low-dose-68-weeks\/","title":{"rendered":"\u4f4e\u5242\u91cfCagriSema\uff1a68\u5468\u51cf\u91cd21%\u7684\u7ed3\u679c\u600e\u4e48\u7406\u89e3\uff1f"},"content":{"rendered":"<div class=\"notranslate\" data-no-translation lang=\"zh-CN\"><div class=\"nhd-news-lesson\"><figure class=\"cover\"><img src=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/nhd-news-20261012-06.webp\" alt=\"\u4e0d\u540c\u5242\u91cf\u7ec4\u5408\u7684\u7814\u7a76\u4e3b\u9898\u63d2\u753b\" width=\"1672\" height=\"941\"><figcaption>\u4e3b\u9898\u7f16\u8f91\u63d2\u753b\uff0c\u975e\u5b9e\u9a8c\u7167\u7247\u3002<\/figcaption><\/figure><p class=\"lead\">\u8fd9\u6b21\u503c\u5f97\u5173\u6ce8\u7684\uff0c\u4e0d\u53ea\u662f21%\u8fd9\u4e2a\u6570\u5b57\uff0c\u800c\u662f\u8f83\u4f4e\u5242\u91cf\u7684\u7ec4\u5408\u4e5f\u505a\u51fa\u4e86\u6548\u679c\u3002REDEFINE 9\u7ed9\u51fa\u7684\u7b54\u6848\uff0c\u4ecd\u7136\u9700\u8981\u653e\u56de\u8bd5\u9a8c\u4eba\u7fa4\u3001\u5bf9\u7167\u548c\u5206\u6790\u65b9\u6cd5\u91cc\u770b\u3002<\/p><section class=\"section\" id=\"section-1\"><h2>\u8fd9\u4e00\u7bc7\u53ea\u770bREDEFINE 9<\/h2><p>9\u670821\u65e5\u7684\u516c\u544a\u540c\u65f6\u63d0\u5230\u4e24\u9879\u8bd5\u9a8c\u3002REDEFINE 9\u7814\u7a76\u8d85\u91cd\u6216\u80a5\u80d6\u6210\u5e74\u4eba\uff0c\u6bd4\u8f83CagriSema\u4e0e\u5b89\u6170\u5242\uff0c\u89c2\u5bdf68\u5468\uff1b\u53e6\u4e00\u9879REIMAGINE 5\u7814\u7a762\u578b\u7cd6\u5c3f\u75c5\u5e76\u4ee5\u66ff\u5c14\u6cca\u80bd\u4e3a\u5bf9\u7167\u3002<\/p><p>\u4e24\u9879\u8bd5\u9a8c\u7684\u4eba\u7fa4\u548c\u5bf9\u7167\u4e0d\u540c\u3002\u8fd9\u91cc\u8ba8\u8bba\u7684\u662fREDEFINE 9\uff0c\u4e0d\u80fd\u628a\u5b83\u768421%\u4e0e\u53e6\u4e00\u9879\u8bd5\u9a8c\u76849.1%\u76f4\u63a5\u5f53\u4f5c\u4e24\u79cd\u836f\u7684\u5dee\u8ddd\u3002<\/p><\/section><section class=\"section\" id=\"section-2\"><h2>21%\u4e0e2%\uff0c\u5dee\u522b\u600e\u6837\u7b97\uff1f<\/h2><p>\u516c\u544a\u62a5\u544a\uff0c1.0\u6beb\u514b\/1.0\u6beb\u514b\u7ec4\u5408\u7ec4\u5e73\u5747\u51cf\u91cd21.0%\uff0c\u5b89\u6170\u5242\u7ec42.0%\uff0c\u91c7\u7528\u7684\u662f\u7597\u6548\u4f30\u8ba1\u53e3\u5f84\u3002\u4e24\u8005\u76f8\u51cf\u4e3a19\u4e2a\u767e\u5206\u70b9\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u5047\u8bbe\u4e24\u7ec4\u8d77\u59cb\u90fd\u4e3a100\u516c\u65a4\uff0c21%\u548c2%\u5206\u522b\u76f8\u5f53\u4e8e\u51cf\u5c1121\u516c\u65a4\u548c2\u516c\u65a4\u3002\u8fd9\u662f\u5e2e\u52a9\u7406\u89e3\u767e\u5206\u6bd4\u7684\u5047\u8bbe\uff0c\u4e0d\u662f\u53c2\u4e0e\u8005\u7684\u5b9e\u9645\u8d77\u59cb\u4f53\u91cd\uff0c\u4e5f\u4e0d\u610f\u5473\u7740\u6bcf\u4e2a\u4eba\u90fd\u8fbe\u5230\u5e73\u5747\u6570\u3002<\/p><aside class=\"helper\"><div class=\"helper-title\">REDEFINE 9\u62a5\u9053\u7684\u4f53\u91cd\u53d8\u5316<\/div><div class=\"table-scroll\"><table class=\"data-table\"><thead><tr><th scope=\"col\">\u7ec4\u522b<\/th><th scope=\"col\">\u5e73\u5747\u51cf\u91cd<\/th><th scope=\"col\">\u5206\u6790\u53e3\u5f84<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">1.0 mg \/ 1.0 mg\u7ec4\u5408<\/th><td>21.0%<\/td><td>\u7597\u6548\u4f30\u8ba1<\/td><\/tr><tr><th scope=\"row\">\u5b89\u6170\u5242<\/th><td>2.0%<\/td><td>\u7597\u6548\u4f30\u8ba1<\/td><\/tr><\/tbody><\/table><\/div><p class=\"helper-note\">\u539f\u59cb\u516c\u544a\u768468\u5468\u7ed3\u679c\uff1b\u5dee19\u4e2a\u767e\u5206\u70b9\uff0c\u4e0d\u662f\u53e6\u4e00\u9879\u66ff\u5c14\u6cca\u80bd\u5bf9\u7167\u8bd5\u9a8c\u3002<\/p><\/aside><\/section><section class=\"section\" id=\"section-3\"><h2>\u4e3a\u4ec0\u4e48\u8bf4\u662f\u8f83\u4f4e\u5242\u91cf\uff1f<\/h2><p>\u8fd9\u91cc\u7684\u201c\u8f83\u4f4e\u201d\uff0c\u6307\u5b83\u4e0e\u8be5\u7ec4\u5408\u5f00\u53d1\u9879\u76ee\u4e2d\u7684\u8f83\u9ad8\u5242\u91cf\u65b9\u6848\u76f8\u6bd4\u3002\u4e24\u4e2a\u6beb\u514b\u6570\u5206\u522b\u5bf9\u5e94\u4e24\u4e2a\u6210\u5206\uff0c\u5e76\u4e0d\u662f\u5408\u8d77\u6765\u53eb\u4f5c\u201c\u4e00\u6beb\u514b\u7ec4\u5408\u201d\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u4e0d\u540c\u5206\u5b50\u7684\u6beb\u514b\u6570\u4e0d\u80fd\u76f4\u63a5\u6bd4\u8f83\u5f3a\u5f31\u3002\u5c31\u50cf\u76d0\u548c\u7cd6\u5404\u653e\u4e00\u514b\uff0c\u4f5c\u7528\u5e76\u4e0d\u76f8\u540c\uff1b\u80bd\u7684\u53d7\u4f53\u4f5c\u7528\u3001\u4f53\u5185\u505c\u7559\u65f6\u95f4\u548c\u5236\u5242\u90fd\u4f1a\u5f71\u54cd\u7ed3\u679c\u3002<\/p><\/section><section class=\"section\" id=\"section-4\"><h2>\u7597\u6548\u4f30\u8ba1\u53e3\u5f84\uff0c\u4e3a\u4ec0\u4e48\u503c\u5f97\u770b\u4e00\u773c\uff1f<\/h2><p>\u4e34\u5e8a\u8bd5\u9a8c\u4f1a\u7528\u4e0d\u540c\u65b9\u5f0f\u5904\u7406\u505c\u836f\u3001\u6551\u63f4\u6cbb\u7597\u548c\u7f3a\u5931\u6570\u636e\u3002\u7597\u6548\u4f30\u8ba1\u901a\u5e38\u56de\u7b54\u66f4\u63a5\u8fd1\u201c\u6309\u7814\u7a76\u6cbb\u7597\u6301\u7eed\u4f7f\u7528\uff0c\u4f1a\u600e\u6837\u201d\u7684\u95ee\u9898\uff0c\u53e6\u4e00\u7c7b\u53e3\u5f84\u5219\u66f4\u5f3a\u8c03\u4e0d\u8bba\u662f\u5426\u6301\u7eed\u4f7f\u7528\u7684\u6574\u4f53\u60c5\u51b5\u3002<\/p><p>\u516c\u544a\u7ed9\u51fa\u7684\u662f\u9876\u7ebf\u7ed3\u679c\uff0c\u8fd8\u4e0d\u662f\u6240\u6709\u7ec6\u8282\u5b8c\u6574\u516c\u5f00\u7684\u8bba\u6587\u3002\u6bd4\u8f83\u5176\u4ed6\u7814\u7a76\u65f6\uff0c\u5148\u786e\u8ba4\u5206\u6790\u53e3\u5f84\u4e00\u81f4\uff0c\u907f\u514d\u628a\u4e24\u4e2a\u4e0d\u540c\u95ee\u9898\u7684\u7b54\u6848\u6df7\u5728\u4e00\u8d77\u3002<\/p><\/section><section class=\"section\" id=\"section-5\"><h2>\u9664\u4e86\u51cf\u91cd\uff0c\u8fd8\u7f3a\u54ea\u4e9b\u4fe1\u606f\uff1f<\/h2><p>\u540e\u7eed\u5b8c\u6574\u62a5\u544a\u5e94\u5e2e\u52a9\u6211\u4eec\u4e86\u89e3\u4e0d\u826f\u53cd\u5e94\u3001\u505c\u836f\u6bd4\u4f8b\u3001\u4e0d\u540c\u5242\u91cf\u8868\u73b0\u548c\u4e2a\u4f53\u5dee\u5f02\u3002\u516c\u544a\u79f0\u6574\u4f53\u8010\u53d7\u60c5\u51b5\u4e0e\u65e2\u5f80\u7814\u7a76\u4e00\u81f4\uff0c\u8fd9\u4e0d\u80fd\u66ff\u4ee3\u5177\u4f53\u7684\u4e0d\u826f\u53cd\u5e94\u6570\u5b57\u3002<\/p><p>\u8fd9\u6761\u6d88\u606f\u652f\u6301\u7ee7\u7eed\u7814\u7a76\u8f83\u4f4e\u5242\u91cf\u7ec4\u5408\u7684\u4ef7\u503c\u3002\u5b83\u4e0d\u6784\u6210\u81ea\u884c\u62fc\u914d\u3001\u52a0\u91cf\u6216\u6362\u836f\u7684\u4f9d\u636e\u3002<\/p><\/section><section class=\"section\" id=\"section-6\"><h2>\u4e3a\u4ec0\u4e48\u4e0d\u80fd\u6309\u6beb\u514b\u6570\u7ed9\u4e24\u79cd\u836f\u6392\u540d\uff1f<\/h2><p>\u6beb\u514b\u662f\u8d28\u91cf\u5355\u4f4d\uff0c\u4e0d\u662f\u4f5c\u7528\u5f3a\u5ea6\u5355\u4f4d\u3002\u4e0d\u540c\u5206\u5b50\u5728\u53d7\u4f53\u4e0a\u4f5c\u7528\u7684\u65b9\u5f0f\u3001\u5438\u6536\u4e0e\u6e05\u9664\u60c5\u51b5\u4e0d\u540c\uff0c\u6240\u4ee5\u201c\u6beb\u514b\u8f83\u5c11\u201d\u4e0d\u81ea\u52a8\u7b49\u4e8e\u201c\u836f\u6548\u8f83\u5f31\u201d\u3002<\/p><p>\u540c\u4e00\u5206\u5b50\u7684\u5242\u91cf\u7814\u7a76\uff0c\u5e94\u5728\u76f8\u8fd1\u6761\u4ef6\u4e0b\u6bd4\u8f83\uff1b\u4e0d\u540c\u5206\u5b50\u7684\u7597\u6548\u6bd4\u8f83\uff0c\u5219\u6700\u597d\u770b\u76f4\u63a5\u5bf9\u7167\u8bd5\u9a8c\u3002\u628a\u4e0d\u540c\u7814\u7a76\u7684\u6700\u5927\u6570\u5b57\u6458\u51fa\u6765\uff0c\u5e38\u4f1a\u5ffd\u7565\u4eba\u7fa4\u548c\u65f6\u95f4\u5dee\u5f02\u3002<\/p><\/section><aside class=\"takeaway\"><strong>\u8bfb\u8fd9\u7bc7\u65f6\uff0c\u8bb0\u4f4f\u8fd9\u4e00\u70b9<\/strong><p>21%\u4e0e2%\u7684\u5dee\u8ddd\u662f19\u4e2a\u767e\u5206\u70b9\uff0c\u5c5e\u4e8e\u7279\u5b9a\u8bd5\u9a8c\u53ca\u5206\u6790\u53e3\u5f84\uff0c\u4e0d\u662f\u6240\u6709\u5242\u91cf\u3001\u6240\u6709\u4eba\u7684\u7edf\u4e00\u7ed3\u679c\u3002<\/p><\/aside><section class=\"materials\" id=\"materials\"><div class=\"eyebrow\">\u76f8\u5173\u7814\u7a76\u6750\u6599<\/div><h2>\u67e5\u770b\u6750\u6599\u4e0e\u5206\u6790\u8d44\u6599<\/h2><p class=\"materials-intro\">cagrilintide\u76ee\u5f55\u8d44\u6599\u9002\u5408\u6838\u5bf9\u80f0\u6dc0\u7d20\u76f8\u5173\u5b9e\u9a8c\u6750\u6599\u3002\u7814\u7a76\u539f\u6599\u4e0eREDEFINE 9\u7684\u4e34\u5e8a\u7ec4\u5408\u5236\u5242\u5e76\u4e0d\u7b49\u540c\u3002<\/p><div class=\"product-grid\"><article class=\"product-card\"><div class=\"card-head\"><div><div class=\"product-label\">\u80f0\u6dc0\u7d20\u76f8\u5173\u7814\u7a76<\/div><h3>\u5361\u683c\u5217\u80bd \u00b7 Cagrilintide<\/h3><\/div><\/div><div class=\"card-body\"><p>\u67e5\u770b\u5355\u4e00\u7814\u7a76\u6750\u6599\u7684\u89c4\u683c\uff0c\u53e6\u884c\u786e\u8ba4\u7ec4\u5408\u5236\u5242\u6761\u4ef6\u3002<\/p><a href=\"https:\/\/nhdbio.com\/cn\/%e4%ba%a7%e5%93%81\/%e5%8d%a1%e6%a0%bc%e6%9e%97%e8%83%b0%e5%b2%9b%e7%b4%a0\/\" target=\"_blank\" rel=\"noopener\">\u67e5\u770b\u4ea7\u54c1\u8d44\u6599 \u2192<\/a><\/div><\/article><\/div><\/section><section class=\"sources\" id=\"sources\"><h2>\u539f\u59cb\u8d44\u6599<\/h2><div>\u8d44\u6599\u65e5\u671f\uff1a2026-09-21 \u00b7 \u4e09\u671f\u8bd5\u9a8c\u9876\u7ebf\u516c\u544a<\/div><ul><li><a href=\"https:\/\/www.novonordisk.com\/news-and-media\/news-and-ir-materials\/news-details.html?id=916774\" target=\"_blank\" rel=\"noopener\">\u539f\u59cb\u516c\u544a\uff0f\u7814\u7a76\u53d1\u5e03\u9875\u9762 \u2197<\/a><\/li><\/ul><\/section><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u8fd9\u6b21\u503c\u5f97\u5173\u6ce8\u7684\uff0c\u4e0d\u53ea\u662f21%\u8fd9\u4e2a\u6570\u5b57\uff0c\u800c\u662f\u8f83\u4f4e\u5242\u91cf\u7684\u7ec4\u5408\u4e5f\u505a\u51fa\u4e86\u6548\u679c\u3002REDEFINE 9\u7ed9\u51fa\u7684\u7b54\u6848\uff0c\u4ecd\u7136\u9700\u8981\u653e\u56de\u8bd5\u9a8c\u4eba\u7fa4\u3001\u5bf9\u7167\u548c\u5206\u6790\u65b9\u6cd5\u91cc\u770b\u3002<\/p>","protected":false},"author":1,"featured_media":4283,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"320","pim_article_type":"Published research explained","pim_evidence_level":"Phase three trial top-line announcement","pim_reviewer":"AI-assisted source and editorial check","pim_reviewed_date":"2026-10-12","pim_editorial_note":"Original public sources, study populations and limitations are linked. Editorial illustrations are not experimental photographs.","pim_review_status":"reviewed","pim_review_reason":"Reviewed Chinese source, protected scientific values and links, unique illustration, related product families and responsive layout checked.","pim_creation_method":"AI-assisted writing","pim_sources":"[{\"title\":\"Technical reference \u2014 www.novonordisk.com \u2014 news-details.html\",\"note\":\"\",\"url\":\"https:\/\/www.novonordisk.com\/news-and-media\/news-and-ir-materials\/news-details.html?id=916774\"}]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-4284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Low-dose CagriSema: understanding 21% weight loss at 68 weeks | NHD<\/title>\n<meta name=\"description\" content=\"What is worth noting this time is not just the number of 21%, but that the lower-dose combination also produced an effect. The answer given by REDEFINE 9 still needs to be viewed in the context of the trial population, comparator, and analysis method.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/cn\/cagrisema-\u91cd\u65b0\u5b9a\u4e499\u4f4e\u5242\u91cf68\u5468\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Low-dose CagriSema: understanding 21% weight loss at 68 weeks\" \/>\n<meta property=\"og:description\" content=\"What is worth noting this time is not just the number of 21%, but that the lower-dose combination also produced an effect. 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