{"id":4292,"date":"2026-10-12T08:32:37","date_gmt":"2026-10-12T08:32:37","guid":{"rendered":"https:\/\/nhdbio.com\/?p=4292"},"modified":"2026-10-12T08:32:37","modified_gmt":"2026-10-12T08:32:37","slug":"%e6%9b%bf%e5%b0%94%e6%b3%8a%e8%82%bd%e8%b6%85%e8%b6%8acvot%e8%80%81%e5%b9%b4%e5%b9%b4%e9%be%84%e5%88%86%e6%9e%90","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/tirzepatide-surpass-cvot-older-age-analysis\/","title":{"rendered":"\u66ff\u5c14\u6cca\u80bd\u5728\u8001\u5e74\u60a3\u8005\u4e2d\u8868\u73b0\u600e\u6837\uff1f\u770b\u61c2SURPASS-CVOT\u5e74\u9f84\u5206\u6790"},"content":{"rendered":"<div class=\"notranslate\" data-no-translation lang=\"zh-CN\"><div class=\"nhd-news-lesson\"><figure class=\"cover\"><img src=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/nhd-news-20261012-07.webp\" alt=\"\u8001\u5e74\u4eba\u7fa4\u5fc3\u8840\u7ba1\u7814\u7a76\u8d44\u6599\u8ba8\u8bba\u7684\u4e3b\u9898\u63d2\u753b\" width=\"1672\" height=\"941\"><figcaption>\u4e3b\u9898\u7f16\u8f91\u63d2\u753b\uff0c\u975e\u5b9e\u9a8c\u7167\u7247\u3002<\/figcaption><\/figure><p class=\"lead\">\u5e74\u8f7b\u4eba\u548c\u8001\u5e74\u4eba\u7684\u57fa\u7840\u75c5\u3001\u7528\u836f\u548c\u8010\u53d7\u60c5\u51b5\u5e38\u6709\u4e0d\u540c\u3002EASD\u7684\u4e00\u4efd\u65b0\u6d77\u62a5\u628aSURPASS-CVOT\u6309\u5e74\u9f84\u62c6\u5f00\u6765\u770b\uff0c\u91cd\u70b9\u662f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff0c\u800c\u4e0d\u53ea\u662f\u51cf\u4e86\u591a\u5c11\u4f53\u91cd\u3002<\/p><section class=\"section\" id=\"section-1\"><h2>\u8fd9\u662f\u4e00\u9879\u5927\u8bd5\u9a8c\u91cc\u9762\u7684\u5e74\u9f84\u5206\u6790<\/h2><p>\u539f\u8bd5\u9a8c\u6bd4\u8f83\u66ff\u5c14\u6cca\u80bd\u4e0e\u5ea6\u62c9\u7cd6\u80bd\uff0c\u53c2\u4e0e\u8005\u60a3\u67092\u578b\u7cd6\u5c3f\u75c5\u5e76\u5df2\u6709\u5fc3\u8840\u7ba1\u75be\u75c5\uff0c\u4e2d\u4f4d\u6cbb\u7597\u65f6\u95f4\u7ea64\u5e74\u3002\u5b83\u7684\u5bf9\u7167\u662f\u53e6\u4e00\u79cd\u6709\u6548\u836f\u7269\uff0c\u4e0d\u662f\u5b89\u6170\u5242\u3002<\/p><p>9\u670829\u65e5\u5c55\u793a\u7684\u9884\u8bbe\u5206\u6790\u5206\u6210\u4e09\u7ec4\uff1a65\u5c81\u4ee5\u4e0b\u300165\u5c81\u81f3\u4e0d\u8db375\u5c81\u300175\u5c81\u53ca\u4ee5\u4e0a\u3002\u201c\u9884\u8bbe\u201d\u8868\u793a\u8fd9\u9879\u5e74\u9f84\u6bd4\u8f83\u4e8b\u5148\u5c31\u8ba1\u5212\u4e86\uff0c\u4f46\u5b83\u4ecd\u7136\u5c5e\u4e8e\u539f\u8bd5\u9a8c\u7684\u4e9a\u7ec4\u5206\u6790\u3002<\/p><\/section><section class=\"section\" id=\"section-2\"><h2>\u4e09\u4e2a\u5e74\u9f84\u7ec4\uff0c\u4e3b\u8981\u5fc3\u8840\u7ba1\u7ed3\u679c\u600e\u4e48\u770b\uff1f<\/h2><p>\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u3001\u5fc3\u808c\u6897\u6b7b\u548c\u5352\u4e2d\u5408\u5728\u4e00\u8d77\uff0c\u662f\u6d77\u62a5\u4e2d\u7684\u4e09\u9879\u590d\u5408\u7ec8\u70b9\u3002\u66ff\u5c14\u6cca\u80bd\u76f8\u5bf9\u5ea6\u62c9\u7cd6\u80bd\u7684\u98ce\u9669\u6bd4\uff0c\u4e09\u4e2a\u5e74\u9f84\u7ec4\u4f9d\u6b21\u4e3a0.87\u30010.98\u548c0.87\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u98ce\u9669\u6bd41\u53ef\u4ee5\u7406\u89e3\u4e3a\u4e24\u7ec4\u76f8\u5f53\uff0c\u4f4e\u4e8e1\u8868\u793a\u4f30\u8ba1\u65b9\u5411\u504f\u5411\u8f83\u5c11\u4e8b\u4ef6\u3002\u4f46\u4e09\u4e2a\u5e74\u9f84\u7ec4\u768495%\u7f6e\u4fe1\u533a\u95f4\u90fd\u5305\u542b1\uff0c\u6240\u4ee5\u4e0d\u80fd\u53ea\u63110.87\u8bf4\u201c\u8001\u5e74\u4eba\u5df2\u88ab\u8bc1\u660e\u83b7\u76ca13%\u201d\u3002<\/p><aside class=\"helper\"><div class=\"helper-title\">\u4e09\u9879\u5fc3\u8840\u7ba1\u7ec8\u70b9\uff1a\u66ff\u5c14\u6cca\u80bd\u5bf9\u6bd4\u5ea6\u62c9\u7cd6\u80bd<\/div><div class=\"table-scroll\"><table class=\"data-table\"><thead><tr><th scope=\"col\">\u5e74\u9f84\u7ec4<\/th><th scope=\"col\">\u98ce\u9669\u6bd4<\/th><th scope=\"col\">95%\u7f6e\u4fe1\u533a\u95f4<\/th><\/tr><\/thead><tbody><tr><th scope=\"row\">\uff1c65\u5c81<\/th><td>0.87<\/td><td>0.75\u20131.02<\/td><\/tr><tr><th scope=\"row\">65\u5c81\u81f3\uff1c75\u5c81<\/th><td>0.98<\/td><td>0.85\u20131.13<\/td><\/tr><tr><th scope=\"row\">\u226575\u5c81<\/th><td>0.87<\/td><td>0.69\u20131.10<\/td><\/tr><\/tbody><\/table><\/div><p class=\"helper-note\">\u539f\u59cb\u6d77\u62a5\u6570\u636e\u3002\u4e09\u4e2a\u533a\u95f4\u5747\u5305\u542b1\uff0c\u4e0d\u80fd\u5206\u522b\u5ba3\u5e03\u4f18\u4e8e\u5bf9\u7167\u3002<\/p><\/aside><\/section><section class=\"section\" id=\"section-3\"><h2>\u7f6e\u4fe1\u533a\u95f4\uff0c\u50cf\u7ed9\u4f30\u8ba1\u503c\u7559\u51fa\u4e00\u6bb5\u8303\u56f4<\/h2><p>75\u5c81\u53ca\u4ee5\u4e0a\u7ec4\u7684\u98ce\u9669\u6bd4\u4e3a0.87\uff0c\u533a\u95f4\u4e3a0.69\u81f31.10\u3002\u6839\u636e\u8fd9\u4efd\u6570\u636e\uff0c\u771f\u5b9e\u5dee\u522b\u53ef\u80fd\u662f\u4e8b\u4ef6\u8f83\u5c11\uff0c\u4e5f\u53ef\u80fd\u6ca1\u6709\u660e\u786e\u5dee\u522b\uff0c\u751a\u81f3\u7565\u591a\u3002\u5355\u770b0.87\u8fd8\u4e0d\u8db3\u4ee5\u5b9a\u8bba\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u5e74\u9f84\u4e0e\u6cbb\u7597\u4e4b\u95f4\u7684\u4ea4\u4e92\u68c0\u9a8c\u6ca1\u6709\u663e\u793a\u660e\u786e\u5dee\u5f02\u3002\u610f\u601d\u662f\uff0c\u76ee\u524d\u6ca1\u6709\u8db3\u591f\u8bc1\u636e\u8bf4\u836f\u7269\u6bd4\u8f83\u7ed3\u679c\u4f1a\u968f\u8fd9\u4e09\u79cd\u5e74\u9f84\u7ec4\u663e\u8457\u6539\u53d8\uff0c\u5e76\u4e0d\u4ee3\u8868\u6bcf\u4e2a\u5e74\u9f84\u3001\u6bcf\u4e2a\u4eba\u7684\u7ed3\u679c\u5b8c\u5168\u4e00\u6837\u3002<\/p><\/section><section class=\"section\" id=\"section-4\"><h2>\u518d\u52a0\u4e00\u4e2a\u7ec8\u70b9\uff0c\u7b54\u6848\u53ef\u80fd\u4e0d\u540c<\/h2><p>\u6d77\u62a5\u8fd8\u770b\u4e86\u56db\u9879\u590d\u5408\u7ec8\u70b9\uff0c\u5728\u524d\u4e09\u9879\u4e4b\u5916\u52a0\u5165\u51a0\u72b6\u52a8\u8109\u8840\u8fd0\u91cd\u5efa\u300275\u5c81\u53ca\u4ee5\u4e0a\u7ec4\u7684\u98ce\u9669\u6bd4\u4e3a0.77\uff0c\u533a\u95f40.62\u81f30.95\u3002<\/p><p>\u8fd9\u4e2a\u7ed3\u679c\u4e0e\u4e09\u9879\u7ec8\u70b9\u4e0d\u77db\u76fe\uff0c\u56e0\u4e3a\u7edf\u8ba1\u7684\u4e8b\u4ef6\u4e0d\u540c\u3002\u51a0\u8109\u8840\u8fd0\u91cd\u5efa\u52a0\u5165\u540e\uff0c\u5c31\u4e0d\u80fd\u518d\u628a\u5b83\u7684\u6570\u5b57\u79f0\u4e3a\u4ec5\u9488\u5bf9\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u3001\u5fc3\u6897\u548c\u5352\u4e2d\u7684\u7ed3\u679c\u3002<\/p><\/section><section class=\"section\" id=\"section-5\"><h2>\u8001\u5e74\u4eba\u8fd8\u8981\u770b\u80fd\u5426\u6301\u7eed\u4f7f\u7528<\/h2><p>75\u5c81\u53ca\u4ee5\u4e0a\u4eba\u7fa4\u4e2d\uff0c\u6d77\u62a5\u62a5\u544a\u56e0\u4e0d\u826f\u4e8b\u4ef6\u505c\u836f\u7684\u6bd4\u4f8b\u7ea6\u4e3a21%\u4e0e17%\uff0c\u5206\u522b\u5bf9\u5e94\u66ff\u5c14\u6cca\u80bd\u548c\u5ea6\u62c9\u7cd6\u80bd\u3002\u8bc4\u4ef7\u8001\u5e74\u60a3\u8005\u65f6\uff0c\u4f53\u91cd\u3001\u8840\u7cd6\u3001\u80c3\u80a0\u9053\u4e0d\u9002\u548c\u505c\u836f\u60c5\u51b5\u90fd\u8981\u4e00\u8d77\u770b\u3002<\/p><p>\u8fd9\u4efd\u5206\u6790\u8865\u5145\u4e86\u9ad8\u5fc3\u8840\u7ba1\u98ce\u9669\u8001\u5e74\u7cd6\u5c3f\u75c5\u4eba\u7fa4\u7684\u8bc1\u636e\u3002\u5b83\u6ca1\u6709\u7814\u7a76\u6240\u6709\u5065\u5eb7\u8001\u5e74\u4eba\uff0c\u4e5f\u4e0d\u80fd\u7531\u6b64\u63a8\u5bfc\u9002\u7528\u4e8e\u6bcf\u4e2a\u4eba\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/p><\/section><section class=\"section\" id=\"section-6\"><h2>\u4e09\u4e2a\u5e74\u9f84\u7ec4\u6ca1\u6709\u660e\u663e\u4ea4\u4e92\u5dee\u5f02\uff0c\u662f\u5426\u8bc1\u660e\u5e74\u9f84\u5b8c\u5168\u4e0d\u91cd\u8981\uff1f<\/h2><p>\u4e0d\u80fd\u3002\u6ca1\u6709\u68c0\u51fa\u5dee\u5f02\uff0c\u4e5f\u53ef\u80fd\u4e0e\u4eba\u6570\u6216\u4e8b\u4ef6\u6570\u91cf\u6709\u5173\u3002\u5e74\u9f84\u4ecd\u4f1a\u5f71\u54cd\u57fa\u7840\u75c5\u3001\u80be\u529f\u80fd\u3001\u8425\u517b\u548c\u8010\u53d7\uff1b\u8fd9\u6b21\u53ea\u56de\u7b54\u76f8\u5e94\u8bd5\u9a8c\u4e2d\u7684\u6cbb\u7597\u6bd4\u8f83\u3002<\/p><p>\u770b\u4e9a\u7ec4\u65f6\uff0c\u6700\u597d\u540c\u65f6\u4fdd\u7559\u6bd4\u8f83\u503c\u4e0e\u533a\u95f4\u3002\u533a\u95f4\u8de8\u8fc71\u65f6\uff0c\u70b9\u4f30\u8ba1\u770b\u8d77\u6765\u8f83\u597d\u4ecd\u6709\u4e0d\u786e\u5b9a\u6027\uff1b\u4e5f\u4e0d\u5e94\u53ea\u6311\u4e00\u4e2a\u8fbe\u5230\u663e\u8457\u6027\u7684\u6b21\u8981\u7ec8\u70b9\u66ff\u4ee3\u4e3b\u8981\u7ec8\u70b9\u3002<\/p><\/section><aside class=\"takeaway\"><strong>\u8bfb\u8fd9\u7bc7\u65f6\uff0c\u8bb0\u4f4f\u8fd9\u4e00\u70b9<\/strong><p>\u6309\u5e74\u9f84\u62c6\u5206\u540e\uff0c\u4e09\u9879\u5fc3\u8840\u7ba1\u7ec8\u70b9\u6ca1\u6709\u8bc1\u660e\u66ff\u5c14\u6cca\u80bd\u5728\u6bcf\u7ec4\u90fd\u4f18\u4e8e\u5ea6\u62c9\u7cd6\u80bd\uff1b\u56db\u9879\u7ec8\u70b9\u9700\u8981\u53e6\u5916\u9605\u8bfb\u3002<\/p><\/aside><section class=\"materials\" id=\"materials\"><div class=\"eyebrow\">\u76f8\u5173\u7814\u7a76\u6750\u6599<\/div><h2>\u67e5\u770b\u6750\u6599\u4e0e\u5206\u6790\u8d44\u6599<\/h2><p class=\"materials-intro\">\u66ff\u5c14\u6cca\u80bd\u76ee\u5f55\u9875\u63d0\u4f9b\u76f8\u5173\u7814\u7a76\u6750\u6599\u4fe1\u606f\u3002\u6d77\u62a5\u4e2d\u7684\u4e34\u5e8a\u836f\u54c1\u53ca\u968f\u8bbf\u6761\u4ef6\uff0c\u4e0e\u76ee\u5f55\u539f\u6599\u4f9b\u5e94\u662f\u4e0d\u540c\u4e8b\u9879\u3002<\/p><div class=\"product-grid\"><article class=\"product-card\"><div class=\"card-head\"><div><div class=\"product-label\">GLP-1 \/ GIP\u76f8\u5173\u7814\u7a76<\/div><h3>\u66ff\u5c14\u6cca\u80bd \u00b7 Tirzepatide<\/h3><\/div><\/div><div class=\"card-body\"><p>\u6838\u5bf9\u7814\u7a76\u6750\u6599\u7684\u8eab\u4efd\u3001\u89c4\u683c\u53ca\u5206\u6790\u8d44\u6599\u3002<\/p><a href=\"https:\/\/nhdbio.com\/cn\/%e4%ba%a7%e5%93%81\/%e8%92%82%e5%b0%94%e6%b3%bd%e5%b8%95%e8%82%bd\/\" target=\"_blank\" rel=\"noopener\">\u67e5\u770b\u4ea7\u54c1\u8d44\u6599 \u2192<\/a><\/div><\/article><\/div><\/section><section class=\"sources\" id=\"sources\"><h2>\u539f\u59cb\u8d44\u6599<\/h2><div>\u8d44\u6599\u65e5\u671f\uff1a2026-09-29 \u00b7 \u968f\u673a\u8bd5\u9a8c\u7684\u9884\u8bbe\u5e74\u9f84\u4e9a\u7ec4\u5206\u6790<\/div><ul><li><a href=\"https:\/\/www.lilly.com\/hcp\/congresses\/easd-2026\" target=\"_blank\" rel=\"noopener\">\u539f\u59cb\u516c\u544a\uff0f\u7814\u7a76\u53d1\u5e03\u9875\u9762 \u2197<\/a><\/li><li><a href=\"https:\/\/www.lrlscience.com\/download\/4rofVQWNm6kPQjJhQ2pYMK\" target=\"_blank\" rel=\"noopener\">EASD 2026\u539f\u59cb\u6d77\u62a5\u53ca\u62a5\u544a \u2197<\/a><\/li><\/ul><\/section><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u5e74\u8f7b\u4eba\u548c\u8001\u5e74\u4eba\u7684\u57fa\u7840\u75c5\u3001\u7528\u836f\u548c\u8010\u53d7\u60c5\u51b5\u5e38\u6709\u4e0d\u540c\u3002EASD\u7684\u4e00\u4efd\u65b0\u6d77\u62a5\u628aSURPASS-CVOT\u6309\u5e74\u9f84\u62c6\u5f00\u6765\u770b\uff0c\u91cd\u70b9\u662f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff0c\u800c\u4e0d\u53ea\u662f\u51cf\u4e86\u591a\u5c11\u4f53\u91cd\u3002<\/p>","protected":false},"author":1,"featured_media":4291,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"370","pim_article_type":"Published research explained","pim_evidence_level":"Prespecified age subgroup analysis of a randomized trial","pim_reviewer":"AI-assisted source and editorial check","pim_reviewed_date":"2026-10-12","pim_editorial_note":"Original public sources, study populations and limitations are linked. 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