{"id":4332,"date":"2026-10-12T08:32:46","date_gmt":"2026-10-12T08:32:46","guid":{"rendered":"https:\/\/nhdbio.com\/?p=4332"},"modified":"2026-10-12T08:32:46","modified_gmt":"2026-10-12T08:32:46","slug":"humanin-%e9%a2%97%e7%b2%92%e7%bb%86%e8%83%9e%e6%b0%a7%e5%8c%96%e5%ba%94%e6%bf%80","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/humanin-granulosa-cell-oxidative-stress\/","title":{"rendered":"Humanin\u600e\u6837\u5e2e\u52a9\u9897\u7c92\u7ec6\u80de\u5e94\u5bf9\u6c27\u5316\u538b\u529b\uff1f"},"content":{"rendered":"<div class=\"notranslate\" data-no-translation lang=\"zh-CN\"><div class=\"nhd-news-lesson\"><figure class=\"cover\"><img src=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/10\/nhd-news-20261012-12.webp\" alt=\"\u9897\u7c92\u7ec6\u80de\u5e94\u5bf9\u6c27\u5316\u538b\u529b\u7684\u4e3b\u9898\u63d2\u753b\" width=\"1672\" height=\"941\"><figcaption>\u4e3b\u9898\u7f16\u8f91\u63d2\u753b\uff0c\u975e\u5b9e\u9a8c\u7167\u7247\u3002<\/figcaption><\/figure><p class=\"lead\">\u5375\u6ce1\u4e2d\u9664\u4e86\u5375\u6bcd\u7ec6\u80de\uff0c\u8fd8\u6709\u4e00\u7fa4\u8d1f\u8d23\u652f\u6301\u5b83\u7684\u9897\u7c92\u7ec6\u80de\u30022026\u5e74\u7684\u4e00\u9879\u7814\u7a76\u89c2\u5bdfHumanin\u80fd\u5426\u5e2e\u52a9\u8fd9\u4e9b\u7ec6\u80de\u5728\u6c27\u5316\u538b\u529b\u4e0b\u5b58\u6d3b\u3002\u7406\u89e3\u8fd9\u9879\u7814\u7a76\uff0c\u8981\u5148\u628a\u7ec6\u80de\u4fdd\u62a4\u4e0e\u751f\u80b2\u7ed3\u679c\u5206\u5f00\u3002<\/p><section class=\"section\" id=\"section-1\"><h2>\u9897\u7c92\u7ec6\u80de\uff0c\u53ef\u4ee5\u7406\u89e3\u4e3a\u5375\u6ce1\u91cc\u7684\u652f\u6301\u56e2\u961f<\/h2><p>\u9897\u7c92\u7ec6\u80de\u53c2\u4e0e\u5375\u6ce1\u73af\u5883\u548c\u6b63\u5e38\u5375\u5de2\u529f\u80fd\u3002\u5982\u679c\u8fd9\u7fa4\u7ec6\u80de\u53d7\u635f\uff0c\u5375\u6ce1\u7684\u72b6\u6001\u4e5f\u53ef\u80fd\u53d7\u5230\u5f71\u54cd\u3002<\/p><p>\u7814\u7a76\u7528\u4e86\u4eba\u9897\u7c92\u7ec6\u80de\u7cfbKGN\u548c\u4f53\u5916\u57f9\u517b\u7684\u5927\u9f20\u5375\u5de2\u7ec4\u7ec7\u3002\u524d\u8005\u4fbf\u4e8e\u89c2\u5bdf\u5355\u7c7b\u7ec6\u80de\uff0c\u540e\u8005\u591a\u4e86\u4e00\u4e9b\u7ec4\u7ec7\u73af\u5883\uff0c\u4f46\u90fd\u4e0d\u662f\u7ed9\u4eba\u4f53\u4f7f\u7528Humanin\u7684\u8bd5\u9a8c\u3002<\/p><\/section><section class=\"section\" id=\"section-2\"><h2>\u7814\u7a76\u600e\u6837\u5236\u9020\u53ef\u6bd4\u8f83\u7684\u538b\u529b\uff1f<\/h2><p>\u4f5c\u8005\u7528\u8fc7\u6c27\u5316\u6c22\u7ed9\u7ec6\u80de\u5236\u9020\u6c27\u5316\u538b\u529b\uff0c\u7136\u540e\u89c2\u5bdf\u6709\u65e0\u989d\u5916Humanin\u65f6\u7684\u53d8\u5316\u3002\u8fd9\u79cd\u6a21\u578b\u4fbf\u4e8e\u63d0\u51fa\u4e00\u4e2a\u660e\u786e\u95ee\u9898\uff1a\u5728\u76f8\u540c\u538b\u529b\u4e0b\uff0c\u7ec6\u80de\u7684\u53cd\u5e94\u6709\u6ca1\u6709\u4e0d\u540c\uff1f<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u4e0d\u8fc7\uff0c\u771f\u5b9e\u5375\u5de2\u4e2d\u7684\u53d8\u5316\u6d89\u53ca\u6fc0\u7d20\u3001\u8840\u6d41\u3001\u5e74\u9f84\u548c\u591a\u7c7b\u7ec6\u80de\u3002\u4e00\u4e2a\u8fc7\u6c27\u5316\u6c22\u6a21\u578b\u65e0\u6cd5\u5305\u542b\u6240\u6709\u56e0\u7d20\uff0c\u7ed3\u679c\u5e94\u6309\u6a21\u578b\u8303\u56f4\u7406\u89e3\u3002<\/p><\/section><section class=\"section\" id=\"section-3\"><h2>\u770b\u5230\u7684\u6539\u5584\uff0c\u5177\u4f53\u5728\u54ea\u91cc\uff1f<\/h2><p>Humanin\u63d0\u9ad8\u4e86\u8fc7\u6c27\u5316\u6c22\u9176\u6d3b\u6027\uff0c\u5e76\u51cf\u5c11\u538b\u529b\u8bf1\u5bfc\u7684\u9897\u7c92\u7ec6\u80de\u51cb\u4ea1\u3002\u90e8\u5206\u4e0e\u51cb\u4ea1\u6709\u5173\u7684\u57fa\u56e0\u8868\u8fbe\u4e5f\u53d1\u751f\u53d8\u5316\uff0c\u5927\u9f20\u7ec4\u7ec7\u5b9e\u9a8c\u63d0\u4f9b\u4e86\u76f8\u5e94\u652f\u6301\u3002<a class=\"source-ref\" href=\"#sources\" aria-label=\"\u67e5\u770b\u539f\u59cb\u6765\u6e90\">[1]<\/a><\/p><p>\u8fc7\u6c27\u5316\u6c22\u9176\u80fd\u5e2e\u52a9\u5904\u7406\u8fc7\u6c27\u5316\u6c22\uff0c\u53ef\u4ee5\u7406\u89e3\u4e3a\u7ec6\u80de\u7684\u4e00\u79cd\u6e05\u7406\u5de5\u5177\u3002\u4f46\u8bba\u6587\u5e76\u6ca1\u6709\u770b\u5230\u6240\u6709\u6297\u6c27\u5316\u6307\u6807\u540c\u6b65\u6539\u53d8\uff0c\u4e0d\u80fd\u6982\u62ec\u6210\u201c\u5168\u90e8\u6297\u6c27\u5316\u7cfb\u7edf\u90fd\u88ab\u589e\u5f3a\u201d\u3002<\/p><\/section><section class=\"section\" id=\"section-4\"><h2>\u4e3a\u4ec0\u4e48\u8981\u540c\u65f6\u770b\u6d3b\u6027\u3001\u57fa\u56e0\u548c\u51cb\u4ea1\uff1f<\/h2><p>\u4e00\u79cd\u68c0\u6d4b\u53ef\u80fd\u53d7\u5230\u6d4b\u91cf\u65b9\u6cd5\u7684\u5f71\u54cd\u3002\u628a\u9176\u6d3b\u6027\u3001\u57fa\u56e0\u8868\u8fbe\u548c\u7ec6\u80de\u51cb\u4ea1\u653e\u5728\u4e00\u8d77\uff0c\u80fd\u4ece\u4e0d\u540c\u4fa7\u9762\u68c0\u67e5\u540c\u4e00\u4e2a\u89e3\u91ca\u3002<\/p><p>\u4f8b\u5982\uff0c\u7ec6\u80de\u770b\u8d77\u6765\u66f4\u6d3b\u8dc3\uff0c\u8fd8\u9700\u8981\u786e\u8ba4\u662f\u5426\u771f\u7684\u5c11\u4e86\u6b7b\u4ea1\u3001\u662f\u4e0d\u662f\u76f8\u5173\u901a\u8def\u4e5f\u6709\u53d8\u5316\u3002\u4e0d\u540c\u8bc1\u636e\u4e92\u76f8\u652f\u6301\uff0c\u6bd4\u53ea\u6311\u4e00\u5f20\u597d\u770b\u7684\u56fe\u66f4\u6709\u610f\u4e49\u3002<\/p><\/section><section class=\"section\" id=\"section-5\"><h2>\u5b83\u80fd\u4e0d\u80fd\u8bf4\u660eHumanin\u63d0\u9ad8\u53d7\u5b55\u7387\uff1f<\/h2><p>\u8fd9\u9879\u7814\u7a76\u6ca1\u6709\u6d4b\u4eba\u4f53\u53d7\u5b55\u7387\uff0c\u4e5f\u6ca1\u6709\u76f4\u63a5\u6bd4\u8f83\u6d3b\u4ea7\u7ed3\u679c\u3002\u5b83\u652f\u6301\u7684\u662f\u7279\u5b9a\u538b\u529b\u6761\u4ef6\u4e0b\u7684\u7ec6\u80de\u4fdd\u62a4\u4f5c\u7528\uff0c\u540e\u7eed\u8fd8\u9700\u7ec4\u7ec7\u3001\u52a8\u7269\u548c\u4eba\u4f53\u7814\u7a76\u9010\u6b65\u68c0\u9a8c\u3002<\/p><p>\u56e0\u6b64\uff0c\u9002\u5408\u5173\u6ce8\u7684\u7814\u7a76\u95ee\u9898\u662f\uff1a\u652f\u6301\u7ec6\u80de\u600e\u6837\u5904\u7406\u538b\u529b\uff0cHumanin\u5728\u54ea\u4e9b\u73af\u8282\u8d77\u4f5c\u7528\uff0c\u4ee5\u53ca\u8fd9\u79cd\u7ec6\u80de\u53d8\u5316\u80fd\u5426\u5f71\u54cd\u66f4\u5b8c\u6574\u7684\u5375\u6ce1\u529f\u80fd\u3002<\/p><\/section><section class=\"section\" id=\"section-6\"><h2>TUNEL\u68c0\u6d4b\u770b\u5230\u7684\u662f\u4ec0\u4e48\uff1f<\/h2><p>\u5b83\u68c0\u6d4b\u4e0e\u7ec6\u80de\u51cb\u4ea1\u6709\u5173\u7684DNA\u53d8\u5316\uff0c\u7528\u6765\u5e2e\u52a9\u8bc6\u522b\u6b63\u5728\u9000\u51fa\u7684\u7ec6\u80de\u3002\u5b83\u63d0\u4f9b\u7684\u662f\u7ec6\u80de\u5c42\u9762\u7684\u7ed3\u679c\uff0c\u4e0d\u76f4\u63a5\u544a\u8bc9\u6211\u4eec\u6574\u4e2a\u5375\u6ce1\u6700\u540e\u80fd\u5426\u6b63\u5e38\u53d1\u80b2\u3002<\/p><p>\u82e5\u53ea\u770b\u4e00\u79cd\u6d3b\u529b\u68c0\u6d4b\uff0c\u53ef\u80fd\u5206\u4e0d\u6e05\u7ec6\u80de\u6570\u589e\u591a\u4e0e\u5355\u4e2a\u7ec6\u80de\u4ee3\u8c22\u53d8\u5f3a\u3002\u7ed3\u5408\u51cb\u4ea1\u3001\u7ec6\u80de\u6570\u91cf\u548c\u5176\u4ed6\u6307\u6807\uff0c\u624d\u66f4\u5bb9\u6613\u89e3\u91ca\u6240\u8c13\u201c\u4fdd\u62a4\u201d\u5177\u4f53\u53d1\u751f\u5728\u54ea\u91cc\u3002<\/p><\/section><aside class=\"takeaway\"><strong>\u8bfb\u8fd9\u7bc7\u65f6\uff0c\u8bb0\u4f4f\u8fd9\u4e00\u70b9<\/strong><p>\u7814\u7a76\u89c2\u5bdf\u4e86\u9897\u7c92\u7ec6\u80de\u548c\u4f53\u5916\u5375\u5de2\u7ec4\u7ec7\uff1b\u6ca1\u6709\u7ed9\u51fa\u4eba\u4f53\u53d7\u5b55\u7387\u6216\u6d3b\u4ea7\u7387\u7684\u7b54\u6848\u3002<\/p><\/aside><section class=\"materials\" id=\"materials\"><div class=\"eyebrow\">\u76f8\u5173\u7814\u7a76\u6750\u6599<\/div><h2>\u67e5\u770b\u6750\u6599\u4e0e\u5206\u6790\u8d44\u6599<\/h2><p class=\"materials-intro\">\u82e5\u5f00\u5c55Humanin\u76f8\u5173\u7ec6\u80de\u5b9e\u9a8c\uff0c\u53ef\u54a8\u8be2\u5b9a\u5236\u80bd\u670d\u52a1\u5e76\u786e\u8ba4\u5e8f\u5217\u53ca\u6eb6\u6db2\u6761\u4ef6\u3002\u672c\u6587\u4e0d\u63d0\u4f9b\u4e0d\u5b58\u5728\u7684Humanin\u76ee\u5f55\u94fe\u63a5\u3002<\/p><div class=\"product-grid\"><article class=\"product-card\"><div class=\"card-head\"><div><div class=\"product-label\">\u5e8f\u5217\u3001\u4fee\u9970\u4e0e\u5206\u6790\u8981\u6c42<\/div><h3>\u5b9a\u5236\u80bd\u670d\u52a1<\/h3><\/div><\/div><div class=\"card-body\"><p>\u8bf4\u660e\u9700\u8981\u7684\u5e8f\u5217\u3001\u672b\u7aef\u5f62\u5f0f\u3001\u6570\u91cf\u53ca\u68c0\u6d4b\u8981\u6c42\uff0c\u6309\u9879\u76ee\u786e\u8ba4\u4ea4\u4ed8\u8303\u56f4\u3002<\/p><a href=\"https:\/\/nhdbio.com\/cn\/%e6%9c%8d%e5%8a%a1\/%e5%ae%9a%e5%88%b6%e8%82%bd%e5%90%88%e6%88%90\/\" target=\"_blank\" rel=\"noopener\">\u4e86\u89e3\u5b9a\u5236\u670d\u52a1 \u2192<\/a><\/div><\/article><\/div><\/section><section class=\"sources\" id=\"sources\"><h2>\u539f\u59cb\u8d44\u6599<\/h2><div>\u8d44\u6599\u65e5\u671f\uff1a2026-07-01 \u00b7 \u7ec6\u80de\u7cfb\uff0b\u4f53\u5916\u7ec4\u7ec7\u7814\u7a76<\/div><ul><li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42397223\/\" target=\"_blank\" rel=\"noopener\">Mitochondrial-derived peptide Humanin protects granulosa cells under oxidative conditions. \u2197<\/a><\/li><li><a href=\"https:\/\/doi.org\/10.1093\/reprod\/xaag082\" target=\"_blank\" rel=\"noopener\">\u8bba\u6587 DOI\uff1a10.1093\/reprod\/xaag082 \u2197<\/a><\/li><\/ul><\/section><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u5375\u6ce1\u4e2d\u9664\u4e86\u5375\u6bcd\u7ec6\u80de\uff0c\u8fd8\u6709\u4e00\u7fa4\u8d1f\u8d23\u652f\u6301\u5b83\u7684\u9897\u7c92\u7ec6\u80de\u30022026\u5e74\u7684\u4e00\u9879\u7814\u7a76\u89c2\u5bdfHumanin\u80fd\u5426\u5e2e\u52a9\u8fd9\u4e9b\u7ec6\u80de\u5728\u6c27\u5316\u538b\u529b\u4e0b\u5b58\u6d3b\u3002\u7406\u89e3\u8fd9\u9879\u7814\u7a76\uff0c\u8981\u5148\u628a\u7ec6\u80de\u4fdd\u62a4\u4e0e\u751f\u80b2\u7ed3\u679c\u5206\u5f00\u3002<\/p>","protected":false},"author":1,"featured_media":4331,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"","pim_article_type":"Published research explained","pim_evidence_level":"Cell line plus in vitro tissue study","pim_reviewer":"AI-assisted source and editorial check","pim_reviewed_date":"2026-10-12","pim_editorial_note":"Original public sources, study populations and limitations are linked. 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A study in 2026 looked at whether Humanin can help these cells survive under oxidative stress. To understand this study, you first need to separate cell protection from fertility outcomes.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/cn\/humanin-\u9897\u7c92\u7ec6\u80de\u6c27\u5316\u5e94\u6fc0\/\" \/>\n<meta property=\"og:locale\" content=\"zh_CN\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Humanin and oxidative stress: what happens in granulosa cells?\" \/>\n<meta property=\"og:description\" content=\"In addition to the oocyte, a follicle also contains a group of granulosa cells that support it. A study in 2026 looked at whether Humanin can help these cells survive under oxidative stress. 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