{"id":756,"date":"2026-09-01T16:45:45","date_gmt":"2026-09-01T16:45:45","guid":{"rendered":"https:\/\/nhdbio.com\/resources\/pt-141-bremelanotide-free-base-acetate-finished-drug-boundary\/"},"modified":"2026-09-01T16:45:45","modified_gmt":"2026-09-01T16:45:45","slug":"pt-141-bremelanotide-free-base-acetate-finished-drug-boundary","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/cn\/pt-141-bremelanotide-free-base-acetate-finished-drug-boundary\/","title":{"rendered":"PT-141\/\u5e03\u96f7\u9ed8\u6d6a\u80bd\uff1a\u6e38\u79bb\u78b1\u3001\u4e59\u9178\u76d0\u548c\u6210\u54c1\u836f\u7269\u8fb9\u754c"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">PT-141 \u662f\u4e0e\u5e03\u96f7\u9ed8\u8bfa\u80bd\u76f8\u5173\u7684\u5f00\u53d1\u4ee3\u7801\u3002\u6e38\u79bb\u78b1\u80bd\u3001\u5176\u918b\u9178\u76d0\u5f62\u5f0f\u548c\u6279\u51c6\u7684\u6210\u54c1\u6ce8\u5c04\u5242\u662f\u76f8\u5173\u8bb0\u5f55\uff0c\u4f46\u5b83\u4eec\u4e0d\u662f\u53ef\u4e92\u6362\u7684\u6750\u6599\u3002<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">\u8bc1\u636e\u4e00\u76ee\u4e86\u7136<\/h2><ul class=\"wp-block-list\"><li>PubChem \u5c06\u5e03\u96f7\u9ed8\u8bfa\u80bd\u6e38\u79bb\u78b1\u5217\u4e3a\u73af\u72b6\u4e03\u6b8b\u57fa\u80bd\uff0c\u5206\u5b50\u91cf\u4e3a 1025.2 g\/mol\u3002<\/li><li>DailyMed \u5c06\u918b\u9178\u5e03\u96f7\u9ed8\u8bfa\u80bd\u5217\u4e3a\u5728 0.3 mL \u6279\u51c6\u7684\u6210\u54c1\u4e2d\u63d0\u4f9b 1.75 \u6beb\u514b\u5e03\u96f7\u9ed8\u8bfa\u80bd\u7684\u6210\u5206\u3002<\/li><li>\u76d1\u7ba1\u6279\u51c6\u9002\u7528\u4e8e\u6307\u5b9a\u7684\u914d\u65b9\u3001\u5236\u9020\u5546\u548c\u6807\u7b7e\uff0c\u800c\u4e0d\u9002\u7528\u4e8e\u6240\u6709\u4f7f\u7528 PT-141 \u4f5c\u4e3a\u540c\u4e49\u8bcd\u7684\u6750\u6599\u3002<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1672\" height=\"941\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary.webp\" alt=\"PT-141\u6e38\u79bb\u78b1\u3001\u918b\u9178\u76d0\u548c\u6210\u54c1\u5236\u5242\u4e4b\u95f4\u7684\u5206\u6790\u533a\u522b\" class=\"wp-image-740\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary.webp 1672w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary-300x169.webp 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary-1024x576.webp 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary-768x432.webp 768w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/bremelanotide-identity-boundary-1536x864.webp 1536w\" sizes=\"auto, (max-width: 1672px) 100vw, 1672px\" \/><figcaption class=\"wp-element-caption\">\u539f\u59cb\u7f16\u8f91\u5206\u6790\u63d2\u56fe\u3002\u5b83\u4e0d\u63cf\u8ff0\u4f9b\u5e94\u7684\u4ea7\u54c1\u3001\u53d1\u5e03\u7684\u6279\u6b21\u3001\u6279\u51c6\u7684\u914d\u65b9\u3001\u6d4b\u5b9a\u7ed3\u679c\u6216\u4e34\u5e8a\u7528\u9014\u3002<\/figcaption><\/figure><h2 class=\"wp-block-heading\">\u8eab\u4efd\u8bb0\u5f55<\/h2><p class=\"wp-block-paragraph\">PubChem \u80bd\u8bb0\u5f55\u5305\u62ec\u5e26\u6709 D-\u82ef\u4e19\u6c28\u9178\u6b8b\u57fa\u7684 N-\u4e59\u9170\u5316\u73af\u72b6\u5e8f\u5217\u3002\u5e8f\u5217\u987a\u5e8f\u3001\u73af\u5316\u548c\u7acb\u4f53\u5316\u5b66\u90fd\u6709\u52a9\u4e8e\u540c\u4e00\u6027\uff1b\u7b80\u77ed\u7684\u8425\u9500\u540d\u79f0\u5e76\u4e0d\u80fd\u6293\u4f4f\u4ed6\u4eec\u7684\u6ce8\u610f\u529b\u3002<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>\u7814\u7a76\u4ee3\u7801<\/strong><span>PT-141<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u6d3b\u6027\u90e8\u5206<\/strong><span>\u5e03\u96f7\u9ed8\u8bfa\u80bd\uff1b PubChem CID 9941379<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u6210\u54c1\u836f\u6210\u5206<\/strong><span>\u918b\u9178\u5e03\u96f7\u9ed8\u8bfa\u80bd<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u8eab\u4efd\u68c0\u67e5<\/strong><span>\u73af\u72b6\u5e8f\u5217\u3001\u7acb\u4f53\u5316\u5b66\u3001\u6297\u8861\u79bb\u5b50\u3001\u8d28\u91cf\u3001\u8272\u8c31\u3001\u542b\u91cf\u548c\u6279\u6b21\u5173\u8054<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">\u5206\u6790\u548c\u8bc1\u636e\u8fb9\u754c<\/h2><p class=\"wp-block-paragraph\">\u918b\u9178\u76d0\u542b\u91cf\u6539\u53d8\u914d\u65b9\u91cd\u91cf\u548c\u542b\u91cf\u8ba1\u7b97\u3002\u8bc1\u4e66\u5e94\u8bf4\u660e\u7ed3\u679c\u662f\u6309\u6e38\u79bb\u78b1\u3001\u918b\u9178\u76d0\u8fd8\u662f\u6309\u539f\u6837\u62a5\u544a\u3002<\/p><p class=\"wp-block-paragraph\">\u5207\u52ff\u501f\u7528 Vyleesi \u9002\u5e94\u75c7\u6216\u5b89\u5168\u6982\u51b5\u4f5c\u4e3a\u76ee\u5f55\u6279\u6b21\u5177\u6709\u6cbb\u7597\u7b49\u6548\u6027\u7684\u8bc1\u636e\u3002\u9002\u5f53\u7684\u8054\u7cfb\u662f\u4e0e\u7a81\u51fa\u7684\u6210\u54c1\u836f\u7269\u8fb9\u754c\u7684\u8bc1\u636e\u80cc\u666f\u8054\u7cfb\u3002<\/p><h2 class=\"wp-block-heading\">\u7f16\u8f91\u89c4\u5219<\/h2><p class=\"wp-block-paragraph\">\u8bf4\u660e\u6240\u5f15\u7528\u8bb0\u5f55\u652f\u6301\u7684\u786e\u5207\u6750\u6599\u3001\u5f62\u5f0f\u3001\u6a21\u578b\u6216\u7fa4\u4f53\u548c\u7ec8\u70b9\u3002\u8bf7\u52ff\u5c06\u673a\u68b0\u5408\u7406\u6027\u3001\u52a8\u7269\u7ed3\u679c\u3001\u6210\u54c1\u836f\u54c1\u6807\u7b7e\u6216\u5206\u6790\u6d4b\u8bd5\u8f6c\u5316\u4e3a\u6709\u5173\u4e0d\u76f8\u5173\u76ee\u5f55\u6279\u6b21\u7684\u58f0\u660e\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>PT-141 \u662f\u4e0e\u5e03\u96f7\u9ed8\u8bfa\u80bd\u76f8\u5173\u7684\u5f00\u53d1\u4ee3\u7801\u3002\u6e38\u79bb\u78b1\u80bd\u3001\u5176\u918b\u9178\u76d0\u5f62\u5f0f\u548c\u6279\u51c6\u7684\u6210\u54c1\u6ce8\u5c04\u5242\u662f\u76f8\u5173\u8bb0\u5f55\uff0c\u4f46\u5b83\u4eec\u4e0d\u662f\u53ef\u4e92\u6362\u7684\u6750\u6599\u3002<\/p>","protected":false},"author":1,"featured_media":740,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"358","pim_article_type":"Evidence and material-quality guide","pim_evidence_level":"FDA label plus curated chemical and peptide identity records","pim_reviewer":"Site evidence editorial team","pim_reviewed_date":"2026-09-02","pim_editorial_note":"Source-checked on 2026-09-02. Null results, study size, model\/population limits and relevant conflicts are retained. This is not medical advice, a customer case or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"Primary\/regulatory sources, factual claims, numerical results, limitations and product-evidence boundary checked for batch 3.","pim_creation_method":"The editorial workflow began with linked PubMed primary papers, systematic reviews, PubChem identity records and FDA\/DailyMed regulatory records. Population or model, denominators, endpoints, numerical results, null findings, limitations and conflicts were extracted before drafting. AI-assisted drafting and original image generation were used; the final facts and evidence boundaries were checked against the linked records on 2026-09-02. This is not independent peer review.","pim_sources":"[{\"title\":\"RECONNECT bremelanotide phase 3 trials\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31599840\/\",\"note\":\"Primary phase 3 publication; PMID 31599840.\"},{\"title\":\"DailyMed Vyleesi prescribing information\",\"url\":\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=f1d0c1b5-2f39-4bad-a6a4-0066e3ad5dcf\",\"note\":\"Current FDA-approved finished-drug label.\"},{\"title\":\"PubChem Bremelanotide record\",\"url\":\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Bremelanotide\",\"note\":\"Free-base peptide identity; CID 9941379.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-756","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>PT-141\/Bremelanotide: Free Base, Acetate and Finished-Drug Boundary<\/title>\n<meta name=\"description\" content=\"PT-141 is the development code associated with bremelanotide. 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