{"id":780,"date":"2026-09-01T17:35:05","date_gmt":"2026-09-01T17:35:05","guid":{"rendered":"https:\/\/nhdbio.com\/resources\/epitalon-aedg-sequence-identity-quality-guide\/"},"modified":"2026-09-08T07:30:41","modified_gmt":"2026-09-08T07:30:41","slug":"epitalon-aedg-sequence-identity-quality-guide","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/de\/epitalon-aedg-sequence-identity-quality-guide\/","title":{"rendered":"Epitalon-Identit\u00e4tsleitfaden: AEDG-Sequenz-, Massen- und Beweisgrenze"},"content":{"rendered":"
Epitalon ist das Tetrapeptid Ala-Glu-Asp-Gly, abgek\u00fcrzt AEDG. Identit\u00e4t, Sequenzbest\u00e4tigung, chromatographische Reinheit und quantitativer Peptidgehalt sind verwandte, aber separate Messungen.<\/p>
Beweise auf einen Blick<\/h2>
PubChem listet die Sequenz AEDG, die Formel C14H22N4O9 und das Molekulargewicht 390.35 g\/mol auf.<\/li>
Epitalon, Epithalon und Epithalone werden als Synonyme angezeigt, Epithalamin bezieht sich jedoch auf einen anderen historischen Extraktkontext und sollte nicht automatisch ausgeblendet werden.<\/li>
Ein Reinheitsprozentsatz gibt keinen Hinweis auf Wasser, Restl\u00f6sungsmittel, Gegenionen oder den absoluten Peptidgehalt.<\/li><\/ul><\/div><\/div>Von AI generierte redaktionelle Illustration zur Veranschaulichung eines analytischen Arbeitsablaufs. Es stellt kein geliefertes Produkt, keine freigegebene Charge, keine genehmigte Formulierung oder kein Testergebnis dar.<\/figcaption><\/figure>
Identit\u00e4tsdatensatz<\/h2>
Die Reihenfolge der vier Reste und die Stereochemie definieren die Referenzverbindung. In einem Zertifikat sollte die molekulare Form angegeben werden, die f\u00fcr die Massenberechnungen verwendet wird, und ob die gemeldete Menge im Ist-Zustand, wasserfrei oder auf Basis des Peptidgehalts angegeben ist.<\/p>
Kernloskontrollen<\/strong>Sequenz oder intakte Masse, Chromatographie, Inhaltsbasis, Wasser, Restl\u00f6sungsmittel und Chargenverkn\u00fcpfung<\/span><\/div><\/div><\/div>
Analyse- und Beweisgrenze<\/h2>
Die Massenspektrometrie unterst\u00fctzt die molekulare Identit\u00e4t, w\u00e4hrend die Chromatographie die Trennung der Hauptkomponenten absch\u00e4tzt. Keiner der Tests allein stellt die biologische Aktivit\u00e4t, Sterilit\u00e4t, Endotoxin, Stabilit\u00e4t oder Eignung f\u00fcr ein bestimmtes Versuchssystem fest.<\/p>
In der Produktkopie sollte \u201ein Zellalterungs- und Maus-Eizellen-Modellen untersucht\u201c stehen. Es sollte nicht die Formulierung \u201everl\u00e4ngert die Lebensspanne\u201c, \u201ekehrt das Altern um\u201c oder eine \u00e4hnliche Formulierung verwendet werden, ohne dass direkte Beweise f\u00fcr kontrollierte Ergebnisse beim Menschen vorliegen.<\/p>
Redaktionelle Regel<\/h2>
Geben Sie das genaue Material, die Form, das Modell oder die Population und den Endpunkt an, die durch den zitierten Datensatz unterst\u00fctzt werden. Wandeln Sie keine mechanistische Plausibilit\u00e4t, ein Tierergebnis, ein offizielles Etikett eines Fertigarzneimittels oder einen analytischen Test in eine Aussage \u00fcber eine nicht verwandte Katalogcharge um.<\/p>","protected":false},"excerpt":{"rendered":"
Epitalon ist das Tetrapeptid Ala-Glu-Asp-Gly, abgek\u00fcrzt AEDG. Identit\u00e4t, Sequenzbest\u00e4tigung, chromatographische Reinheit und quantitativer Peptidgehalt sind verwandte, aber separate Messungen.<\/p>","protected":false},"author":1,"featured_media":764,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"327","pim_article_type":"Evidence and material-quality guide","pim_evidence_level":"PubChem identity record plus primary cell and animal studies","pim_reviewer":"Site evidence editorial team","pim_reviewed_date":"2026-09-02","pim_editorial_note":"Source-checked on 2026-09-02. Null results, sample size, model\/population limits and regulatory scope are retained. This is not medical advice, a customer case or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"Primary and official sources, numerical results, null findings, limitations, product-evidence boundary and image disclosure checked for batch 4.","pim_creation_method":"This article discusses the source records listed below, with the study models and limitations stated alongside the findings. AI-assisted drafting and image generation were used. The reference list identifies the records behind this article; it is not an independent peer review or verification of a supplied catalog lot.","pim_sources":"[{\"title\":\"Epitalon and telomere length in human cell lines\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40908429\/\",\"note\":\"Primary 2025 cell study; PMID 40908429; includes cancer and normal cell lines.\"},{\"title\":\"Epitalon in post-ovulatory aging mouse oocytes\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35413689\/\",\"note\":\"Primary 2022 in-vitro mouse-oocyte study; PMID 35413689.\"},{\"title\":\"PubChem Epitalon record\",\"url\":\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Epitalon\",\"note\":\"Sequence, formula, molecular weight and synonyms; CID 219042.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-780","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"\n
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