{"id":815,"date":"2026-09-01T19:07:33","date_gmt":"2026-09-01T19:07:33","guid":{"rendered":"https:\/\/nhdbio.com\/resources\/hexarelin-human-dose-response-growth-hormone-evidence\/"},"modified":"2026-09-08T07:30:41","modified_gmt":"2026-09-08T07:30:41","slug":"hexarelin-human-dose-response-growth-hormone-evidence","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/de\/hexarelin-human-dose-response-growth-hormone-evidence\/","title":{"rendered":"Hexarelin Human Evidence: Dosis-Wirkung, GH Peak und Grenzwerte"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">Zu Hexarelin liegen kontrollierte Humanpharmakologiedaten vor, der zentrale Beweis ist jedoch ein akutes GH-Dosis-Wirkungs-Experiment mit 12 Personen und nicht eine klinische Ergebnisstudie.<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">Beweise auf einen Blick<\/h2><ul class=\"wp-block-list\"><li>Zw\u00f6lf gesunde M\u00e4nner erhielten in einer doppelblinden Studie mit steigender Dosis Placebo und 0.5, 1 und 2 \u00b5g\/kg Hexarelin intraven\u00f6s.<\/li><li>Der mittlere Spitzenwert GH betrug 3.9, 26.9, 52.3 und 55.0 ng\/ml, mit einem Reaktionsplateau zwischen 1 und 2 \u00b5g\/kg.<\/li><li>GH erreichte seinen H\u00f6hepunkt bei etwa 30 Minuten, kehrte innerhalb von 240 Minuten zum Ausgangswert zur\u00fcck und hatte eine gesch\u00e4tzte Halbwertszeit von etwa 55 Minuten.<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/hexarelin-evidence.webp\" alt=\"Dokumentarisches klinisches Pharmakologielabor f\u00fcr eine \u00dcberpr\u00fcfung der Hexarelin-Evidenz\" class=\"wp-image-799\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/hexarelin-evidence.webp 1536w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/hexarelin-evidence-300x200.webp 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/hexarelin-evidence-1024x683.webp 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/hexarelin-evidence-768x512.webp 768w\" sizes=\"auto, (max-width: 1536px) 100vw, 1536px\" \/><figcaption class=\"wp-element-caption\">Von AI erstellte redaktionelle Illustration zur Veranschaulichung des Forschungsworkflows. Es handelt sich nicht um eine Studienfigur, ein Patientenbild, ein Produktfoto, ein Testergebnis oder ein Kataloglos.<\/figcaption><\/figure><h2 class=\"wp-block-heading\">Studienprotokoll<\/h2><p class=\"wp-block-paragraph\">In der 1994-Studie wurde Placebo nach dem Zufallsprinzip in die Reihenfolge der steigenden Dosen eingef\u00fcgt. Die nahezu identischen mittleren Peaks bei 1 und 2 \u00b5g\/kg sind ein n\u00fctzlicher Plateaubefund und sollten nicht als \u201eh\u00f6her ist immer besser\u201c umgeschrieben werden.<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>Teilnehmer<\/strong><span>12 gesunde erwachsene M\u00e4nner<\/span><\/div><div class=\"pim-evidence-row\"><strong>Design<\/strong><span>Doppelblind, placebokontrolliert, steigende Dosis<\/span><\/div><div class=\"pim-evidence-row\"><strong>Mittlerer GH Cmax<\/strong><span>3.9, 26.9, 52.3 und 55.0 ng\/ml<\/span><\/div><div class=\"pim-evidence-row\"><strong>Gesch\u00e4tzter ED50<\/strong><span>0.50 \u00b5g\/kg nach Cmax; 0.64 \u00b5g\/kg von AUC<\/span><\/div><div class=\"pim-evidence-row\"><strong>Ergebnisgrenze<\/strong><span>Akute Hormonaussch\u00fcttung, kein Krankheits-, Langlebigkeits- oder Leistungsvorteil<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">Ergebnisse im Kontext<\/h2><p class=\"wp-block-paragraph\">In einer sp\u00e4teren Studie mit sechs Personen wurden zwei mit drei t\u00e4glichen subkutanen Verabreichungen verglichen, w\u00e4hrend GH, Prolaktin, ACTH und Cortisol \u00fcber 24 Stunden \u00fcberwacht wurden. Mehrere endokrine Ver\u00e4nderungen untermauern, dass Hexarelin nicht auf eine selektive GH-Nur-Angabe reduziert werden kann.<\/p><p class=\"wp-block-paragraph\">WADA z\u00e4hlt Examorelin\/Hexarelin zu den verbotenen GH-freisetzenden Peptiden. Diese Klassifizierung ist f\u00fcr den Sport relevant, stellt jedoch weder die Wirksamkeit noch die Produktidentit\u00e4t fest.<\/p><h2 class=\"wp-block-heading\">Was die Beweise nicht belegen k\u00f6nnen<\/h2><p class=\"wp-block-paragraph\">Die prim\u00e4re Studie hatte 12 gesunde m\u00e4nnliche Teilnehmer und akute Endpunkte.<\/p><p class=\"wp-block-paragraph\">Es wurden keine K\u00f6rperzusammensetzung, Genesung, Krankheit oder langfristige Sicherheitsergebnisse gemessen.<\/p><p class=\"wp-block-paragraph\">Die endokrine Reaktion eines definierten Versuchsmaterials kann eine Katalogcharge nicht validieren.<\/p>","protected":false},"excerpt":{"rendered":"<p>Zu Hexarelin liegen kontrollierte Humanpharmakologiedaten vor, der zentrale Beweis ist jedoch ein akutes GH-Dosis-Wirkungs-Experiment mit 12 Personen und nicht eine klinische Ergebnisstudie.<\/p>","protected":false},"author":1,"featured_media":799,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"336","pim_article_type":"Published evidence review","pim_evidence_level":"Double-blind 12-person dose-response trial plus small repeated-exposure physiology study","pim_reviewer":"Site evidence editorial team","pim_reviewed_date":"2026-09-02","pim_editorial_note":"Source-checked on 2026-09-02. Null results, sample size, model\/population limits, finished-drug scope, regulatory status and product-evidence boundaries are retained. This is not medical advice, a customer case or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"Primary and official sources, numerical results, null findings, limitations, product-evidence boundary and image disclosure checked for batch 5.","pim_creation_method":"This article discusses the source records listed below, with the study models and limitations stated alongside the findings. AI-assisted drafting and image generation were used. The reference list identifies the records behind this article; it is not an independent peer review or verification of a supplied catalog lot.","pim_sources":"[{\"title\":\"Hexarelin human dose-response study\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7957536\/\",\"note\":\"Double-blind 12-person study; PMID 7957536.\"},{\"title\":\"Repeated Hexarelin administration in healthy men\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11888836\/\",\"note\":\"Six-person 24-hour endocrine study; PMID 11888836.\"},{\"title\":\"PubChem Examorelin record\",\"url\":\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Examorelin\",\"note\":\"Sequence, formula, molecular weight and synonyms; CID 6918297.\"},{\"title\":\"WADA 2026 Prohibited List\",\"url\":\"https:\/\/www.wada-ama.org\/sites\/default\/files\/2025-09\/2026list_en_final_clean_september_2025.pdf\",\"note\":\"Official list includes Examorelin\/Hexarelin.\"}]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-815","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Hexarelin Human Evidence: Dose Response, GH Peak and Limits<\/title>\n<meta name=\"description\" content=\"Hexarelin has controlled human pharmacology data, but the central evidence is an acute 12-person GH dose-response experiment rather than a clinical-outcome\u2026\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/de\/hexarelin-human-dose-response-growth-hormone-evidence\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" 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Technisches Team","image":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","caption":"NHD Technical Team"},"description":"Das technische Team von NHD verwaltet Katalogdokumentationen und Beweiszusammenfassungen f\u00fcr Forschungszwecke. Rezensierte Artikel verweisen auf von Experten begutachtete Artikel, Studienregister und beh\u00f6rdliche Aufzeichnungen, behalten Nullergebnisse und Studieneinschr\u00e4nkungen bei und unterscheiden ver\u00f6ffentlichte Interventionen von Katalogmaterialien. F\u00fcr die Strukturierung kann AI-unterst\u00fctztes Zeichnen verwendet werden; Quellenverkn\u00fcpfungen und Beweisgrenzen bleiben sichtbar. Bei dieser Arbeit handelt es sich nicht um eine unabh\u00e4ngige Begutachtung oder medizinische Beratung.","sameAs":["https:\/\/nhdbio.com"],"url":"https:\/\/nhdbio.com\/de\/author\/qianmiao-technical-team\/"}]}},"_links":{"self":[{"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/posts\/815","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/comments?post=815"}],"version-history":[{"count":2,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/posts\/815\/revisions"}],"predecessor-version":[{"id":1188,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/posts\/815\/revisions\/1188"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/media\/799"}],"wp:attachment":[{"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/media?parent=815"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/categories?post=815"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhdbio.com\/de\/wp-json\/wp\/v2\/tags?post=815"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}