{"id":4128,"date":"2026-10-11T06:38:25","date_gmt":"2026-10-11T06:38:25","guid":{"rendered":"https:\/\/nhdbio.com\/?page_id=4128"},"modified":"2026-10-11T07:41:51","modified_gmt":"2026-10-11T07:41:51","slug":"%e6%ae%8b%e7%95%99%e6%ba%b6%e5%aa%92ppm%e8%a8%88%e7%ae%97%e4%be%8b","status":"publish","type":"page","link":"https:\/\/nhdbio.com\/ja\/analytical-methods\/residual-solvent-ppm-worked-example\/","title":{"rendered":"\u6b8b\u7559\u6eb6\u5a92 ppm\uff1a\u5831\u544a\u66f8\u3092\u5b9f\u969b\u306e\u8cea\u91cf\u306b\u63db\u7b97\u3059\u308b"},"content":{"rendered":"

\u3042\u308b\u5831\u544a\u66f8\u306b\u6eb6\u5a92\u304c 100 ppm \u3068\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f 10 mg \u306e\u7c89\u672b\u30b5\u30f3\u30d7\u30eb\u3067\u306f\u3069\u308c\u304f\u3089\u3044\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u304b\uff1f\u307e\u305a\u3001ppm \u304c\u91cd\u91cf\u3067\u8868\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u305d\u3046\u3059\u308c\u3070\u3001\u63db\u7b97\u306f\u305f\u3063\u305f2\u30b9\u30c6\u30c3\u30d7\u3067\u3059\u3002<\/p>\n

ppm \u306f\u4f55\u3092\u6570\u3048\u3066\u3044\u307e\u3059\u304b\uff1f<\/h2>\n

For a weight-based result, 100 ppm means 100 parts solvent per one million parts sample by weight. One ppm by weight equals 1 \u00b5g\/g, or 1 mg\/kg.<\/p>\n

\u540c\u3058\u7565\u53f7\u3067\u3082\u3001\u5225\u306e\u5834\u9762\u3067\u306f\u57fa\u6e96\u304c\u7570\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u63db\u7b97\u3059\u308b\u524d\u306b\u3001\u6eb6\u5a92\u540d\u3001\u30b5\u30f3\u30d7\u30eb\u306e\u7a2e\u985e\u3001\u65b9\u6cd5\u3092\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

\"\u56f3
\u56f3 1\u3002\u91cd\u91cf\u30d9\u30fc\u30b9\u306e ppm \u306f\u8cea\u91cf\u6bd4\u3092\u8868\u3057\u307e\u3059\u3002<\/figcaption><\/figure>\n

10 mg \u306e\u30b5\u30f3\u30d7\u30eb\u4e2d\u306e 100 ppm \u3092\u63db\u7b97\u3059\u308b<\/h2>\n

First convert 10 mg to 0.010 g. The result is 100 \u00b5g solvent per gram of sample. Multiply: 100 \u00d7 0.010 = 1 \u00b5g solvent, or 0.001 mg.<\/p>\n

A shortcut is solvent \u00b5g = ppm by weight \u00d7 sample mg \u00f7 1,000. Forgetting the mg-to-g conversion gives an answer a thousand times too large.<\/p>\n

\"Figure
Figure 2. 100 ppm by weight in 10 mg corresponds to 1 \u00b5g solvent.<\/figcaption><\/figure>\n

\u5c0f\u306a\u308a\u8a18\u53f7\u306f\u305d\u306e\u307e\u307e\u306b\u3057\u3066\u304f\u3060\u3055\u3044<\/h2>\n

If the result is less than 100 ppm, the same 10 mg sample contains less than 1 \u00b5g of that solvent on this basis. It is an upper-bound statement, not an exact measurement of 1 \u00b5g.<\/p>\n

\u305d\u306e\u4e0a\u9650\u304c\u3042\u306a\u305f\u306e\u7814\u7a76\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u3089\u3001\u5831\u544a\u9650\u754c\u304c\u3069\u306e\u3088\u3046\u306b\u8a2d\u5b9a\u3055\u308c\u305f\u304b\u3092\u5c0b\u306d\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u6eb6\u6db2\u6fc3\u5ea6\u3092\u8a08\u7b97\u3059\u308b\u306b\u306f\u3001\u4f53\u7a4d\u304c\u5fc5\u8981\u3067\u3059<\/h2>\n

Suppose all of the example 1 \u00b5g transfers into a final 2 mL solution without loss. The solvent concentration is then 1 \u00f7 2 = 0.5 \u00b5g\/mL.<\/p>\n

\u6700\u7d42\u4f53\u7a4d\u3068\u79fb\u884c\u306e\u4eee\u5b9a\u304c\u306a\u3051\u308c\u3070\u3001\u7c89\u672b\u306e ppm \u3092\u5358\u7d14\u306b\u6eb6\u6db2\u6fc3\u5ea6\u306b\u5909\u63db\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002ppm \u306f\u5e38\u306b mg\/L \u3068\u4e92\u63db\u3067\u3042\u308b\u3068\u306f\u9650\u308a\u307e\u305b\u3093\u3002<\/p>\n

\"\u56f3
\u56f3 3\u3002\u7c89\u672b\u306e ppm \u3068\u6eb6\u6db2\u6fc3\u5ea6\u306b\u306f\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u60c5\u5831\u304c\u5fc5\u8981\u3067\u3059\u3002<\/figcaption><\/figure>\n

\u6700\u521d\u306b\u8a08\u7b97\u3057\u3001\u305d\u306e\u5f8c\u3067\u7814\u7a76\u8981\u4ef6\u3092\u8a55\u4fa1\u3057\u3066\u304f\u3060\u3055\u3044<\/h2>\n

\u9069\u5408\u6027\u306f\u3001\u6307\u5b9a\u3055\u308c\u305f\u6eb6\u5a92\u3001\u6750\u6599\u3001\u65b9\u6cd5\u3001\u7814\u7a76\u7528\u9014\u306b\u3088\u3063\u3066\u6c7a\u307e\u308a\u307e\u3059\u3002\u8a08\u7b97\u3055\u308c\u305f\u91cf\u3060\u3051\u3067\u306f\u3001\u666e\u904d\u7684\u306b\u8a31\u5bb9\u3055\u308c\u308b\u30ec\u30d9\u30eb\u3092\u78ba\u7acb\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n

20 mg \u7c89\u672b\u306b\u306f\u91cd\u91cf\u6bd4\u3067 250 ppm \u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3069\u306e\u304f\u3089\u3044\u306e\u6eb6\u5a92\u91cf\u3067\u3059\u304b\uff1f<\/strong><\/p>\n
\n\u7b54\u3048\u3092\u898b\u308b<\/summary>\n

250 \u00d7 20 \u00f7 1,000 = 5 \u00b5g, or 0.005 mg.<\/p>\n<\/details>\n<\/div>\n

GHK-Cu \u307e\u305f\u306f MOTS-c \u306e\u6eb6\u5a92\u7d50\u679c\u306b\u3064\u3044\u3066\u306e\u8cea\u554f<\/h2>\n

GHK-Cu \u307e\u305f\u306f MOTS-c \u306b\u3064\u3044\u3066\u3001\u8abf\u67fb\u3057\u3066\u3044\u308b\u6eb6\u5a92\u3092\u6307\u5b9a\u3057\u3001\u305d\u306e\u8a66\u9a13\u304c\u5b9f\u65bd\u3055\u308c\u305f\u304b\u3069\u3046\u304b\u3092\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u4e00\u822c\u7684\u306a\u7d14\u5ea6\u306e\u8a18\u8ff0\u3067\u306f\u3001\u6b8b\u7559\u6eb6\u5a92\u306e\u7d50\u679c\u3092\u78ba\u7acb\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n

GHK-Cu<\/a> \/ MOTS-c<\/a><\/p>\n

\u8cc7\u6750\u304a\u3088\u3073\u6587\u66f8\u306e\u8981\u4ef6\u306b\u3064\u3044\u3066NHD\u3068\u76f8\u8ac7\u3059\u308b<\/a> \u00b7 \u5206\u6790\u30ac\u30a4\u30c9\u3092\u7d9a\u3051\u308b<\/a><\/p>\n