{"id":3117,"date":"2026-10-04T13:31:46","date_gmt":"2026-10-04T13:31:46","guid":{"rendered":"https:\/\/nhdbio.com\/?p=3117"},"modified":"2026-10-04T15:11:54","modified_gmt":"2026-10-04T15:11:54","slug":"%e9%87%8d%e3%83%9a%e3%83%97%e3%83%81%e3%83%89%e5%90%8c%e4%bd%8d%e4%bd%93%e6%bf%83%e7%b8%ae%e3%81%a8%e5%8c%96%e5%ad%a6%e7%b4%94%e5%ba%a6%e3%81%ae%e9%81%95%e3%81%84","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ja\/heavy-peptide-isotopic-enrichment-chemical-purity-difference\/","title":{"rendered":"\u91cd\u3044\u30da\u30d7\u30c1\u30c9\uff1a99% \u540c\u4f4d\u4f53\u6fc3\u7e2e\u306f 99% \u5316\u5b66\u7d14\u5ea6\u3067\u306f\u3042\u308a\u307e\u305b\u3093"},"content":{"rendered":"<p>\u91cd\u3044\u30da\u30d7\u30c1\u30c9\u306e\u4ed5\u69d8\u306b\u306f\u8907\u6570\u306e\u30d1\u30fc\u30bb\u30f3\u30c6\u30fc\u30b8\u304c\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u3089\u306f\u4e92\u63db\u53ef\u80fd\u306b\u898b\u3048\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u554f\u3044\u306b\u7b54\u3048\u308b\u3082\u306e\u3067\u3059\u3002\u540c\u4f4d\u4f53\u6fc3\u7e2e\u306f\u6a19\u8b58\u3055\u308c\u305f\u539f\u5b50\u3092\u8868\u3057\u3001\u5316\u5b66\u7d14\u5ea6\u306f\u660e\u8a18\u3055\u308c\u305f\u5206\u6790\u6cd5\u306e\u4e0b\u3067\u306e\u6750\u6599\u306e\u7d44\u6210\u3092\u8868\u3057\u307e\u3059\u3002<\/p>\n<h2>\u5b9f\u969b\u306e\u30ab\u30bf\u30ed\u30b0\u4f8b\u304c\u9055\u3044\u3092\u793a\u3059<\/h2>\n<p>Sigma-Aldrich\u2019s catalogue entry for L-lysine-13C6,15N2 hydrochloride lists 99 atom % carbon-13 and 99 atom % nitrogen-15, alongside an assay of 95% (CP). This is a labelled amino-acid building block, not a finished peptide. Its separate specification fields make the distinction visible: high isotope enrichment is not a statement that the whole material has the same chemical purity.<\/p>\n<h2>\u5b8c\u6210\u3057\u305f\u91cd\u3044\u30da\u30d7\u30c1\u30c9\u306b\u306f\u4f55\u3092\u6307\u5b9a\u3059\u3079\u304d\u304b\uff1f<\/h2>\n<p>\u3069\u306e\u6b8b\u57fa\u304c\u6a19\u8b58\u3092\u62c5\u3044\u3001\u3069\u306e\u539f\u5b50\u304c\u7f6e\u63db\u3055\u308c\u3066\u3044\u308b\u304b\u3092\u8a18\u9332\u3057\u307e\u3059\u3002\u6b21\u306b\u5316\u5b66\u7d14\u5ea6\u306e\u8981\u4ef6\u3092\u5225\u9014\u660e\u8a18\u3057\u307e\u3059\u3002\u5b9a\u91cf\u7684\u306a\u4f5c\u696d\u3067\u306f\u3001\u30da\u30d7\u30c1\u30c9\u91cf\u307e\u305f\u306f\u6fc3\u5ea6\u304c\u3069\u306e\u3088\u3046\u306b\u6c7a\u5b9a\u3055\u308c\u308b\u304b\u3082\u78ba\u8a8d\u3057\u307e\u3059\u3002\u6a19\u8b58\u3055\u308c\u305f\u914d\u5217\u3001\u540c\u4f4d\u4f53\u6fc3\u7e2e\u5024\u3001\u304a\u3088\u3073HPLC\u7d14\u5ea6\u7d50\u679c\u306f\u3001\u5185\u90e8\u6a19\u6e96\u3068\u3057\u3066\u306e\u6b63\u78ba\u306a\u91cf\u3092\u81ea\u52d5\u7684\u306b\u78ba\u7acb\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h2>\u8efd\u3044\u6750\u6599\u304c\u554f\u984c\u3068\u306a\u308b\u7406\u7531<\/h2>\n<p>\u91cd\u3044\u6a19\u6e96\u54c1\u306f\u3057\u3070\u3057\u3070\u975e\u6a19\u8b58\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u4f75\u7528\u3055\u308c\u307e\u3059\u3002\u6a19\u6e96\u54c1\u306b\u8efd\u3044\u6750\u6599\u304c\u542b\u307e\u308c\u3066\u3044\u308b\u3068\u3001\u8efd\u3044\u30c1\u30e3\u30cd\u30eb\u306e\u6e2c\u5b9a\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u304c\u554f\u984c\u3068\u306a\u308b\u304b\u3069\u3046\u304b\u306f\u3001\u30a2\u30c3\u30bb\u30a4\u7bc4\u56f2\u3068\u5206\u6790\u30ef\u30fc\u30af\u30d5\u30ed\u30fc\u306b\u3088\u308a\u307e\u3059\u3002\u540c\u4f4d\u4f53\u6fc3\u7e2e\u306e\u30d1\u30fc\u30bb\u30f3\u30c6\u30fc\u30b8\u304c\u3059\u3079\u3066\u306e\u5e72\u6e09\u3092\u6392\u9664\u3059\u308b\u3068\u4eee\u5b9a\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u95a2\u9023\u3059\u308b\u8efd\u3044\u30b3\u30f3\u30bf\u30df\u30cd\u30fc\u30b7\u30e7\u30f3\u8a55\u4fa1\u306b\u3064\u3044\u3066\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h2>\u540c\u6761\u4ef6\u3067\u306e\u6bd4\u8f03\u3092\u4fdd\u3064<\/h2>\n<p>\u898b\u7a4d\u3082\u308a\u3092\u6bd4\u8f03\u3059\u308b\u3068\u304d\u306f\u3001\u540c\u3058\u914d\u5217\u3001\u6a19\u8b58\u4f4d\u7f6e\u3001\u672b\u7aef\u5f62\u614b\u3001\u7d14\u5ea6\u6cd5\u3001\u304a\u3088\u3073\u91cf\u306e\u5272\u308a\u5f53\u3066\u57fa\u6e96\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u3069\u306e\u7d50\u679c\u304c\u5b8c\u6210\u30da\u30d7\u30c1\u30c9\u3067\u6e2c\u5b9a\u3055\u308c\u3001\u3069\u308c\u304c\u51fa\u767a\u6750\u6599\u3092\u8868\u3057\u3066\u3044\u308b\u304b\u3092\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u4e0a\u8a18\u306e\u30ab\u30bf\u30ed\u30b0\u756a\u53f7\u306f\u7528\u8a9e\u3092\u8aac\u660e\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001NHD \u6750\u6599\u3092\u8a8d\u8a3c\u3057\u305f\u308a\u3001\u666e\u904d\u7684\u306a\u8a31\u5bb9\u9650\u754c\u3092\u78ba\u7acb\u3057\u305f\u308a\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h2>NHD\u3067\u306e\u6b21\u306e\u30b9\u30c6\u30c3\u30d7<\/h2>\n<p>\u4ee5\u4e0b\u306e\u95a2\u9023\u88fd\u54c1\u30ab\u30fc\u30c9\u306f\u3001\u30ab\u30bf\u30ed\u30b0\u4e0a\u306e\u30da\u30d7\u30c1\u30c9\u30d5\u30a1\u30df\u30ea\u30fc\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u30d3\u30aa\u30c1\u30f3\u5316\u3001\u86cd\u5149\u6a19\u8b58\u3001\u540c\u4f4d\u4f53\u6a19\u8b58\u3001\u307e\u305f\u306f\u30e9\u30a4\u30d6\u30e9\u30ea\u7248\u306e\u5165\u624b\u53ef\u80fd\u6027\u3092\u78ba\u8a8d\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4fee\u98fe\u7269\u8cea\u306b\u3064\u3044\u3066\u306f\u3001\u30ab\u30b9\u30bf\u30e0\u306e\u304a\u554f\u3044\u5408\u308f\u305b\u3067\u6b63\u78ba\u306a\u8a2d\u8a08\u3092\u6307\u5b9a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u307e\u305a\u306f <a href=\"https:\/\/nhdbio.com\/ja\/%e5%ae%89%e5%ae%9a%e5%90%8c%e4%bd%8d%e4%bd%93%e6%a8%99%e8%ad%98%e3%83%9a%e3%83%97%e3%83%81%e3%83%89%e7%99%ba%e6%b3%a8%e3%83%81%e3%82%a7%e3%83%83%e3%82%af%e3%83%aa%e3%82%b9%e3%83%88\/\">\u91cd\u30da\u30d7\u30c1\u30c9\u767a\u6ce8\u30ac\u30a4\u30c9<\/a>\u304b\u3089\u59cb\u3081\u3066\u304f\u3060\u3055\u3044\u3002\u898b\u7a4d\u3082\u308a\u306e\u3054\u4f9d\u983c\u306f\u3001 <a href=\"https:\/\/nhdbio.com\/ja\/%e5%bc%95%e7%94%a8\/\">NHD\u307e\u3067\u914d\u5217\u307e\u305f\u306f\u88fd\u54c1\u540d\u3001\u6570\u91cf\u3001\u5fc5\u8981\u306a\u66f8\u985e\u3092\u304a\u9001\u308a\u304f\u3060\u3055\u3044<\/a>\u3002\u3054\u6ce8\u6587\u524d\u306b\u3001\u6b63\u78ba\u306a\u5f62\u614b\u3001\u5b9f\u73fe\u53ef\u80fd\u6027\u3001\u5229\u7528\u53ef\u80fd\u306a\u691c\u67fb\u3001\u7d0d\u54c1\u6761\u4ef6\u3092\u3054\u78ba\u8a8d\u304f\u3060\u3055\u3044\u3002<\/p>\n<h2>\u60c5\u5831\u6e90<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.sigmaaldrich.com\/US\/en\/product\/aldrich\/608041\">Sigma-Aldrich\uff1a\u6fc3\u7e2e\u3068\u30a2\u30c3\u30bb\u30a4\u306e\u30d5\u30a3\u30fc\u30eb\u30c9\u304c\u5225\u3005<\/a><\/li>\n<li><a href=\"https:\/\/www.jpt.com\/products-services\/peptide-modifications\/isotope-labeled-peptides\/\">JPT\uff1a\u540c\u4f4d\u4f53\u6a19\u8b58\u30da\u30d7\u30c1\u30c9<\/a><\/li>\n<\/ul>\n<p>\u516c\u958b\u53c2\u8003\u6587\u732e\u306f\u3053\u306e\u30c8\u30d4\u30c3\u30af\u3092\u8aac\u660e\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001NHD \u30d0\u30c3\u30c1\u306e\u8a3c\u62e0\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7814\u7a76\u7528\u6750\u6599\u306f\u5b9f\u9a13\u5ba4\u3067\u306e\u7814\u7a76\u3001\u958b\u767a\u3001\u88fd\u9020\u7528\u3067\u3042\u308a\u3001\u30d2\u30c8\u307e\u305f\u306f\u7363\u533b\u5b66\u7528\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u91cd\u3044\u30da\u30d7\u30c1\u30c9\u306e\u4ed5\u69d8\u306b\u306f\u8907\u6570\u306e\u30d1\u30fc\u30bb\u30f3\u30c6\u30fc\u30b8\u304c\u542b\u307e\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u3089\u306f\u4e92\u63db\u53ef\u80fd\u306b\u898b\u3048\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u305d\u308c\u305e\u308c\u7570\u306a\u308b\u554f\u3044\u306b\u7b54\u3048\u308b\u3082\u306e\u3067\u3059\u3002\u540c\u4f4d\u4f53\u6fc3\u7e2e\u306f\u6a19\u8b58\u3055\u308c\u305f\u539f\u5b50\u3092\u8868\u3057\u3001\u5316\u5b66\u7d14\u5ea6\u306f\u660e\u8a18\u3055\u308c\u305f\u5206\u6790\u6cd5\u306e\u4e0b\u3067\u306e\u6750\u6599\u306e\u7d44\u6210\u3092\u8868\u3057\u307e\u3059\u3002<\/p>","protected":false},"author":1,"featured_media":3113,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"344,369","pim_article_type":"Peptide buying and basics","pim_evidence_level":"Technical references and labeled calculations","pim_reviewer":"Codex AI editorial","pim_reviewed_date":"2026-10-04","pim_editorial_note":"Public data and labeled teaching calculations; not NHD batch results. Confirm project and document availability.","pim_review_status":"reviewed","pim_review_reason":"Source, arithmetic, identity and search-intent checks. No independent human technical review recorded.","pim_creation_method":"AI-assisted writing, source checks and illustrated cover.","pim_sources":"[{\"title\":\"Sigma-Aldrich: separate enrichment and assay fields\",\"url\":\"https:\/\/www.sigmaaldrich.com\/US\/en\/product\/aldrich\/608041\",\"note\":\"Public reference, not NHD batch evidence.\"},{\"title\":\"JPT: isotope-labelled peptides\",\"url\":\"https:\/\/www.jpt.com\/products-services\/peptide-modifications\/isotope-labeled-peptides\/\",\"note\":\"Public reference, not NHD batch evidence.\"}]","footnotes":""},"categories":[20],"tags":[],"class_list":["post-3117","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-quality-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Heavy peptides: 99% isotope enrichment is not 99% chemical purity - NHD<\/title>\n<meta name=\"description\" content=\"Peptide Raw Materials and Custom Peptide Synthesis\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/ja\/\u91cd\u30da\u30d7\u30c1\u30c9\u540c\u4f4d\u4f53\u6fc3\u7e2e\u3068\u5316\u5b66\u7d14\u5ea6\u306e\u9055\u3044\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Heavy peptides: 99% isotope enrichment is not 99% chemical purity\" \/>\n<meta property=\"og:description\" content=\"A heavy peptide specification may contain several percentages. They can look interchangeable, but they answer different questions. 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