{"id":3432,"date":"2026-10-05T03:27:51","date_gmt":"2026-10-05T03:27:51","guid":{"rendered":"https:\/\/nhdbio.com\/?p=3432"},"modified":"2026-10-05T03:27:51","modified_gmt":"2026-10-05T03:27:51","slug":"mots-c-%e9%81%8b%e5%8b%95-%e5%86%85%e5%9b%a0%e6%80%a7%e5%af%be-%e6%8a%95%e4%b8%8e-%e7%a0%94%e7%a9%b6","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ja\/mots-c-exercise-endogenous-versus-administered-study\/","title":{"rendered":"MOTS-c\u3068\u904b\u52d5\uff1a\u81ea\u7136\u306a\u5897\u52a0\u306f\u88dc\u5145\u306e\u7d50\u679c\u3067\u306f\u306a\u3044"},"content":{"rendered":"<p>MOTS-c\u306f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2DNA\u5185\u306b\u30b3\u30fc\u30c9\u3055\u308c\u305f\u77ed\u3044\u30da\u30d7\u30c1\u30c9\u3067\u3059\u3002\u5e83\u304f\u8b70\u8ad6\u3055\u308c\u3066\u3044\u308b\u904b\u52d5\u8ad6\u6587\u306b\u306f2\u7a2e\u985e\u306e\u7570\u306a\u308b\u8a3c\u62e0\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u8005\u306fMOTS-c\u3092\u30de\u30a6\u30b9\u306b\u6295\u4e0e\u3057\u3001\u30d2\u30c8\u3067\u306f\u904b\u52d5\u5f8c\u306b\u81ea\u7136\u306b\u7523\u751f\u3055\u308c\u308bMOTS-c\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u90e8\u5206\u3092\u5206\u3051\u3066\u304a\u304f\u3068\u3001\u77e5\u898b\u304c\u305a\u3063\u3068\u7406\u89e3\u3057\u3084\u3059\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<h2>\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u306f\u4f55\u304c\u8d77\u3053\u3063\u305f\u306e\u304b\uff1f<\/h2>\n<p>\u8ad6\u6587\u306f\u30012\u300112\u300122\u304b\u6708\u9f62\u306e\u7fa4\u3092\u542b\u3080\u3001\u82e5\u9f62\u3001\u4e2d\u5e74\u3001\u8001\u9f62\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u8eab\u4f53\u80fd\u529b\u306e\u6539\u5584\u3092\u8a18\u8f09\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u300123.5\u304b\u6708\u9f62\u3067\u59cb\u307e\u308b\u5f8c\u671f\u5bff\u547d\u5b9f\u9a13\u306b\u3064\u3044\u3066\u3082\u5831\u544a\u3057\u3066\u304a\u308a\u3001\u90313\u56de\u306e\u9593\u6b20\u7684\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u5e74\u9f62\u3068\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u306f\u7814\u7a76\u30c7\u30b6\u30a4\u30f3\u3092\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306f\u30d2\u30c8\u6cbb\u7642\u3078\u306e\u63db\u7b97\u8868\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h2>\u30d2\u30c8\u306e\u90e8\u5206\u3067\u306f\u4f55\u304c\u8d77\u3053\u3063\u305f\u306e\u304b\uff1f<\/h2>\n<p>\u904b\u52d5\u306f\u9aa8\u683c\u7b4b\u304a\u3088\u3073\u5faa\u74b0\u306b\u304a\u3051\u308b\u5185\u56e0\u6027MOTS-c\u767a\u73fe\u3092\u5897\u52a0\u3055\u305b\u307e\u3057\u305f\u3002\u5185\u56e0\u6027\u3068\u306f\u4f53\u5185\u3067\u7523\u751f\u3055\u308c\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u3053\u306e\u89b3\u5bdf\u306f\u3001\u88fd\u9020\u3055\u308c\u305f\u30da\u30d7\u30c1\u30c9\u3092\u8ab0\u304b\u306b\u4e0e\u3048\u3066\u305d\u306e\u4eba\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u6539\u5584\u3059\u308b\u304b\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u3068\u306f\u7570\u306a\u308a\u307e\u3059\u3002\u6284\u9332\u306f\u3001\u30d2\u30c8\u3078\u306e\u88dc\u5145\u306e\u5229\u76ca\u3001\u6709\u52b9\u7528\u91cf\u3001\u307e\u305f\u306f\u9577\u671f\u5b89\u5168\u6027\u3092\u78ba\u7acb\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<h2>\u305d\u308c\u30922\u3064\u306e\u7570\u306a\u308b\u554f\u3044\u3068\u8003\u3048\u3066\u304f\u3060\u3055\u3044<\/h2>\n<p>\u52d5\u7269\u306b\u95a2\u3059\u308b\u554f\u3044\u306f\u3001\u6295\u4e0e\u3055\u308c\u305f\u7269\u8cea\u304c\u5bfe\u7167\u5b9f\u9a13\u4e0b\u3067\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u3092\u5909\u5316\u3055\u305b\u305f\u304b\u3069\u3046\u304b\u3067\u3057\u305f\u3002\u30d2\u30c8\u306b\u95a2\u3059\u308b\u554f\u3044\u306f\u3001\u904b\u52d5\u304c\u81ea\u7136\u306b\u751f\u3058\u308b\u30b7\u30b0\u30ca\u30eb\u306e\u5909\u5316\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3067\u3057\u305f\u3002\u751f\u7269\u5b66\u7684\u30b7\u30b0\u30ca\u30eb\u306f\u3001\u904b\u52d5\u4e2d\u306b\u4e0a\u6607\u3057\u3066\u3082\u3001\u305d\u308c\u3092\u4eba\u5de5\u7684\u306b\u9ad8\u3081\u308b\u3053\u3068\u304c\u904b\u52d5\u3092\u518d\u73fe\u3059\u308b\u8a3c\u62e0\u306b\u306f\u306a\u308a\u307e\u305b\u3093\u3002\u540c\u3058\u533a\u5225\u306f\u591a\u304f\u306e\u30db\u30eb\u30e2\u30f3\u3084\u4ee3\u8b1d\u7269\u306b\u3082\u5f53\u3066\u306f\u307e\u308a\u307e\u3059\u3002<\/p>\n<h2>\u6709\u7528\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\u6bd4\u8f03\u306b\u306f\u4f55\u3092\u542b\u3081\u308b\u3079\u304d\u3067\u3059\u304b\uff1f<\/h2>\n<p>\u7a2e\u3001\u5e74\u9f62\u3001\u904b\u52d5\u30c6\u30b9\u30c8\u3001\u304a\u3088\u3073\u30da\u30d7\u30c1\u30c9\u304c\u6e2c\u5b9a\u3055\u308c\u305f\u304b\u6295\u4e0e\u3055\u308c\u305f\u304b\u3092\u8a18\u9332\u3057\u307e\u3059\u3002\u6b21\u306b\u3001\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u304c\u5b9f\u969b\u306b\u4f55\u3092\u610f\u5473\u3057\u305f\u304b\u3092\u7279\u5b9a\u3057\u307e\u3059\u3002\u6301\u4e45\u529b\u3001\u8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study explanation","pim_evidence_level":"Mouse intervention plus human exercise-associated observations","pim_reviewer":"Codex AI editorial","pim_reviewed_date":"2026-10-05","pim_editorial_note":"Study results and labeled examples are separated. 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A widely discussed exercise paper contains two different kinds of evidence: researchers adminis\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/ja\/mots-c-\u904b\u52d5-\u5185\u56e0\u6027\u5bfe-\u6295\u4e0e-\u7814\u7a76\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MOTS-c and exercise: natural increases are not supplementation results\" \/>\n<meta property=\"og:description\" content=\"MOTS-c is a short peptide encoded within mitochondrial DNA. 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