{"id":453,"date":"2026-08-27T10:31:11","date_gmt":"2026-08-27T10:31:11","guid":{"rendered":"https:\/\/nhdbio.com\/tesamorelin-hiv-lipodystrophy-randomized-trials\/"},"modified":"2026-08-28T07:31:46","modified_gmt":"2026-08-28T07:31:46","slug":"tesamorelin-hiv-lipodystrophy-randomized-trials","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ja\/tesamorelin-hiv-lipodystrophy-randomized-trials\/","title":{"rendered":"Tesamorelin \u304a\u3088\u3073 HIV \u95a2\u9023\u306e\u30ea\u30dd\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc: \u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u3067\u6e2c\u5b9a\u3055\u308c\u305f\u3082\u306e"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">Tesamorelin \u306f\u3001HIV \u95a2\u9023\u30ea\u30dd\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u306e\u6210\u4eba\u306b\u304a\u3051\u308b\u660e\u78ba\u306a\u81e8\u5e8a\u7684\u8a3c\u62e0\u3092\u6301\u3064\u6210\u9577\u30db\u30eb\u30e2\u30f3\u653e\u51fa\u56e0\u5b50\u30a2\u30ca\u30ed\u30b0\u3067\u3059\u3002\u7279\u5b9a\u306e\u96c6\u56e3\u3068\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306e\u72b6\u6cc1\u304c\u91cd\u8981\u3067\u3059\u3002\u8a3c\u62e0\u3092\u5e83\u7bc4\u306a\u6d88\u8cbb\u8005\u306e\u6e1b\u91cf\u4e3b\u5f35\u306b\u4e00\u822c\u5316\u3059\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">\u91cd\u8981\u306a\u30dd\u30a4\u30f3\u30c8<\/h2><ul class=\"wp-block-list\"><li>\u91cd\u8981\u306a\u7814\u7a76\u3067\u306f\u3001HIV\u306b\u95a2\u9023\u3059\u308b\u8179\u90e8\u8102\u80aa\u84c4\u7a4d\u306e\u3042\u308b\u6210\u4eba\u306e\u5185\u81d3\u8102\u80aa\u7d44\u7e54\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002<\/li><li>FDA \u30e9\u30d9\u30eb\u306b\u306f\u3001\u627f\u8a8d\u3055\u308c\u305f\u88fd\u54c1\u304c\u6e1b\u91cf\u7ba1\u7406\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u304c\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li><li>\u627f\u8a8d\u3055\u308c\u305f\u88fd\u54c1\u306e\u8a3c\u62e0\u306f\u3001\u72ec\u7acb\u3057\u3066\u63d0\u4f9b\u3055\u308c\u305f\u7814\u7a76\u8cc7\u6599\u3068\u306e\u540c\u7b49\u6027\u3092\u78ba\u7acb\u3057\u307e\u305b\u3093\u3002<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1672\" height=\"941\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research.png\" alt=\"HIV \u95a2\u9023\u306e\u30ea\u30dd\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u7814\u7a76\u3067\u533f\u540d\u5316\u3055\u308c\u305f\u8179\u90e8\u753b\u50cf\u3092\u30ec\u30d3\u30e5\u30fc\u3059\u308b\u7814\u7a76\u8005\" class=\"wp-image-444\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research.png 1672w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research-300x169.png 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research-1024x576.png 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research-768x432.png 768w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/tesamorelin-hiv-visceral-fat-research-1536x864.png 1536w\" sizes=\"auto, (max-width: 1672px) 100vw, 1672px\" \/><figcaption class=\"wp-element-caption\">HIV \u95a2\u9023\u306e\u30ea\u30dd\u30b8\u30b9\u30c8\u30ed\u30d5\u30a3\u30fc\u7814\u7a76\u306b\u304a\u3051\u308b\u8179\u90e8\u753b\u50cf\u30ec\u30d3\u30e5\u30fc\u306e\u5143\u306e\u7de8\u96c6\u7528\u30a4\u30e9\u30b9\u30c8\u3002\u60a3\u8005\u3082\u88fd\u54c1\u3082\u63cf\u304b\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/figcaption><\/figure><h2 class=\"wp-block-heading\">\u751f\u7269\u5b66\u7684\u304a\u3088\u3073\u81e8\u5e8a\u7684\u80cc\u666f<\/h2><p class=\"wp-block-paragraph\">Tesamorelin \u306f\u6210\u9577\u30db\u30eb\u30e2\u30f3\u653e\u51fa\u56e0\u5b50\u306e\u985e\u4f3c\u4f53\u3067\u3059\u3002\u7814\u7a76\u3055\u308c\u305f\u74b0\u5883\u3067\u306f\u3001\u4e0b\u5782\u4f53\u6210\u9577\u30db\u30eb\u30e2\u30f3\u306e\u653e\u51fa\u3092\u523a\u6fc0\u3057\u3001IGF-1\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u5897\u52a0\u3055\u305b\u307e\u3059\u3002\u95a2\u9023\u3059\u308b\u8a66\u9a13\u306b\u306f\u3001\u6297\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u7642\u6cd5\u3092\u53d7\u3051\u3066\u8179\u90e8\u8102\u80aa\u304c\u904e\u5270\u306aHIV\u3092\u60a3\u3046\u4eba\u3005\u304c\u53c2\u52a0\u3057\u305f\u3002<\/p><p class=\"wp-block-paragraph\">HIV \u95a2\u9023\u306e\u8102\u80aa\u7570\u6804\u990a\u75c7\u306f\u4e00\u822c\u7684\u306a\u80a5\u6e80\u3068\u4e92\u63db\u6027\u304c\u306a\u304f\u3001\u753b\u50cf\u51e6\u7406\u306b\u3088\u3063\u3066\u6e2c\u5b9a\u3055\u308c\u308b\u5185\u81d3\u8102\u80aa\u7d44\u7e54\u306f\u5168\u4f53\u7684\u306a\u4f53\u91cd\u6e1b\u5c11\u3068\u540c\u3058\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3067\u306f\u306a\u3044\u305f\u3081\u3001\u3053\u306e\u6587\u8108\u306f\u91cd\u8981\u3067\u3059\u3002<\/p><h2 class=\"wp-block-heading\">12 \u6708\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u7814\u7a76\u3067\u5224\u660e\u3057\u305f\u3053\u3068<\/h2><p class=\"wp-block-paragraph\">404 \u53c2\u52a0\u8005\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u7814\u7a76\u3067\u306f\u3001\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u3068\u3057\u3066\u5185\u81d3\u8102\u80aa\u7d44\u7e54\u304c\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002\u7814\u7a76\u8005\u3089\u306f\u3001\u6700\u521d\u306e\u7121\u4f5c\u70ba\u5316\u6bb5\u968e\u3067\u5185\u81d3\u8102\u80aa\u304c\u6e1b\u5c11\u3057\u3001\u6cbb\u7642\u3092\u7d99\u7d9a\u3057\u305f\u53c2\u52a0\u8005\u306e\u9593\u3067\u6301\u7d9a\u6027\u304c\u3042\u3063\u305f\u3053\u3068\u3092\u5831\u544a\u3057\u305f\u3002\u30c6\u30b5\u30e2\u30ec\u30ea\u30f3\u304b\u3089\u30d7\u30e9\u30bb\u30dc\u306b\u5207\u308a\u66ff\u3048\u305f\u5f8c\u306f\u6539\u5584\u304c\u5931\u308f\u308c\u3001\u3053\u308c\u306f\u3001\u89b3\u5bdf\u3055\u308c\u305f\u52b9\u679c\u304c\u305d\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u3067\u306e\u7d99\u7d9a\u66dd\u9732\u306b\u4f9d\u5b58\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p><p class=\"wp-block-paragraph\">\u5c0f\u898f\u6a21\u306a\u30e9\u30f3\u30c0\u30e0\u5316\u7814\u7a76\u3067\u306f\u3001\u809d\u81d3\u8102\u80aa\u3068\u5185\u81d3\u8102\u80aa\u7d44\u7e54\u3082\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u306f\u809d\u81d3\u95a2\u9023\u306e\u8ee2\u5e30\u3092\u63a2\u7d22\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u627f\u8a8d\u3055\u308c\u305f\u809d\u75be\u60a3\u306e\u9069\u5fdc\u306b\u5909\u63db\u3055\u308c\u308b\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>\u4eba\u53e3<\/strong><span>HIV \u304a\u3088\u3073\u904e\u5270\u306a\u8179\u90e8\u8102\u80aa\u306e\u3042\u308b\u6210\u4eba<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u4e00\u6b21\u6e2c\u5b9a<\/strong><span>\u753b\u50cf\u306b\u3088\u308b\u5185\u81d3\u8102\u80aa\u7d44\u7e54<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u91cd\u8981\u306a\u5236\u9650\u4e8b\u9805<\/strong><span>\u4e00\u822c\u7684\u306a\u4f53\u91cd\u7ba1\u7406\u96c6\u56e3\u3084\u9069\u5fdc\u75c7\u3067\u306f\u3042\u308a\u307e\u305b\u3093<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">\u3059\u3079\u3066\u306e\u30b5\u30de\u30ea\u30fc\u306b\u5c5e\u3059\u308b\u30e9\u30d9\u30eb\u5883\u754c<\/h2><p class=\"wp-block-paragraph\">2025 EGRIFTA WR \u30e9\u30d9\u30eb\u306f\u3001\u7279\u5b9a\u306e\u627f\u8a8d\u3055\u308c\u305f\u88fd\u5264\u3068\u9069\u5fdc\u75c7\u3092\u8b58\u5225\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u9577\u671f\u7684\u306a\u5fc3\u81d3\u8840\u7ba1\u3078\u306e\u5b89\u5168\u6027\u306f\u78ba\u7acb\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u3053\u306e\u88fd\u54c1\u306f\u6e1b\u91cf\u7ba1\u7406\u306b\u306f\u9069\u5fdc\u3055\u308c\u3066\u3044\u306a\u3044\u3053\u3068\u306b\u3082\u8a00\u53ca\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5236\u9650\u306f\u8a3c\u62e0\u306e\u4e00\u90e8\u3067\u3042\u308a\u3001\u30aa\u30d7\u30b7\u30e7\u30f3\u306e\u7d30\u304b\u3044\u90e8\u5206\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>HIV\u306b\u95a2\u9023\u3059\u308b\u8179\u90e8\u8102\u80aa\u84c4\u7a4d\u306e\u3042\u308b\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u305f\u30c6\u30b5\u30e2\u30ec\u30ea\u30f3\u8a66\u9a13\u306e\u8a3c\u62e0\u306b\u57fa\u3065\u304f\u30ec\u30d3\u30e5\u30fc\u3002\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u3001\u9650\u754c\u5024\u3001FDA\u3067\u30e9\u30d9\u30eb\u4ed8\u3051\u3055\u308c\u305f\u6587\u8108\u304c\u542b\u307e\u308c\u308b\u3002<\/p>","protected":false},"author":1,"featured_media":623,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"367","pim_article_type":"Clinical evidence review","pim_evidence_level":"Randomized controlled human trials and FDA labeling","pim_reviewer":"NHD evidence editorial workflow","pim_reviewed_date":"2026-08-27","pim_editorial_note":"Source-checked against the linked primary or authoritative records on 2026-08-27. This is an evidence summary, not independent peer review, medical advice or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"At least two linked primary or authoritative records and an explicit evidence boundary are present.","pim_creation_method":"The editorial workflow starts with linked peer-reviewed papers, trial registries or regulatory records; extracts the population or model, endpoints, numerical results and limitations; and separates the studied intervention from catalog material. AI-assisted drafting was used to structure the first version. Claims, figures, evidence labels and limitations were checked against the linked records in the site editorial workflow. This is not independent peer review.","pim_sources":"[{\"title\":\"Randomized tesamorelin trial with 12-month extension\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20101189\/\",\"note\":\"Primary human trial; PMID 20101189.\"},{\"title\":\"Randomized trial of visceral and liver fat outcomes\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25038357\/\",\"note\":\"Exploratory liver-fat evidence; PMID 25038357.\"},{\"title\":\"FDA EGRIFTA WR prescribing information\",\"url\":\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2025\/022505s020lbl.pdf\",\"note\":\"Approved-product indication and limitations.\"}]","footnotes":""},"categories":[18],"tags":[],"class_list":["post-453","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-evidence-reviews"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Tesamorelin and HIV-Associated Lipodystrophy: What Randomized Trials Measured - 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