{"id":478,"date":"2026-08-28T06:56:06","date_gmt":"2026-08-28T06:56:06","guid":{"rendered":"https:\/\/nhdbio.com\/cjc-1295-dac-healthy-adult-gh-igf1-trial-data\/"},"modified":"2026-08-28T07:42:46","modified_gmt":"2026-08-28T07:42:46","slug":"cjc-1295-dac-healthy-adult-gh-igf1-trial-data","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/ja\/cjc-1295-dac-healthy-adult-gh-igf1-trial-data\/","title":{"rendered":"\u5065\u5eb7\u306a\u6210\u4eba\u306b\u304a\u3051\u308b CJC-1295 \u3068 DAC: GH\u3001IGF-1 \u304a\u3088\u3073\u534a\u6e1b\u671f\u30c7\u30fc\u30bf"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">\u53e4\u5178\u7684\u306a CJC-1295 \u306e\u30d2\u30c8\u8ad6\u6587\u3067\u306f\u3001\u5065\u5eb7\u306a\u6210\u4eba\u306b\u304a\u3051\u308b\u9577\u6642\u9593\u4f5c\u7528\u578b\u30a2\u30eb\u30d6\u30df\u30f3\u7d50\u5408\u985e\u4f3c\u4f53\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u6301\u7d9a\u7684\u306a\u30db\u30eb\u30e2\u30f3\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u7814\u7a76\u5bfe\u8c61\u306e DAC \u30d5\u30a9\u30fc\u30e0\u306e\u8a3c\u62e0\u3067\u3042\u308a\u3001CJC-1295 \u306e\u540d\u524d\u3067\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u3059\u3079\u3066\u306e\u88fd\u54c1\u306e\u8a3c\u62e0\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">\u8a18\u9332\u304c\u793a\u3059\u3082\u306e<\/h2><ul class=\"wp-block-list\"><li>\u3053\u306e\u5831\u544a\u66f8\u306f\u300128\u65e5\u306849\u65e5\u9593\u7d99\u7d9a\u3057\u305f2\u3064\u306e\u7121\u4f5c\u70ba\u5316\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u4e8c\u91cd\u76f2\u691c\u6f38\u5897\u7528\u91cf\u8a66\u9a13\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u3082\u306e\u3067\u3042\u308b\u3002<\/li><li>\u5e73\u5747 GH \u306f\u3001\u5c11\u306a\u304f\u3068\u3082 6 \u65e5\u9593\u30012 \u500d\u304b\u3089 10 \u500d\u306b\u4e0a\u6607\u3057\u307e\u3057\u305f\u3002\u5e73\u5747 IGF-1 \u306f\u30011 \u56de\u6295\u4e0e\u5f8c 9 \uff5e 11 \u65e5\u9593\u30011.5 \u500d\u304b\u3089 3 \u500d\u306b\u4e0a\u6607\u3057\u307e\u3057\u305f\u3002<\/li><li>\u63a8\u5b9a\u534a\u6e1b\u671f\u306f 5.8 \uff5e 8.1 \u65e5\u3067\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u7d50\u5408\u8a2d\u8a08\u3068\u4e00\u81f4\u3057\u307e\u3057\u305f\u3002<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/gh-secretagogue-research-20260828.png\" alt=\"\u62cd\u52d5\u6027\u6210\u9577\u30db\u30eb\u30e2\u30f3\u3068IGF-1\u306e\u7814\u7a76\u30c7\u30fc\u30bf\u3092\u691c\u8a0e\u3059\u308b\u79d1\u5b66\u8005\" class=\"wp-image-459\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/gh-secretagogue-research-20260828.png 1536w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/gh-secretagogue-research-20260828-300x200.png 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/gh-secretagogue-research-20260828-1024x683.png 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/gh-secretagogue-research-20260828-768x512.png 768w\" sizes=\"auto, (max-width: 1536px) 100vw, 1536px\" \/><figcaption class=\"wp-element-caption\">\u7814\u7a76\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u306e\u30aa\u30ea\u30b8\u30ca\u30eb\u306e\u7de8\u96c6\u7528\u30a4\u30e9\u30b9\u30c8\u3002\u3053\u308c\u306f\u3001\u7814\u7a76\u306e\u56f3\u3001\u60a3\u8005\u306e\u753b\u50cf\u3001\u4f9b\u7d66\u3055\u308c\u305f\u88fd\u54c1\u306e\u5199\u771f\u3001\u307e\u305f\u306f\u6cbb\u9a13\u6750\u6599\u306e\u8868\u73fe\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/figcaption><\/figure><h2 class=\"wp-block-heading\">\u5b66\u7fd2\u8a18\u9332<\/h2><p class=\"wp-block-paragraph\">\u3053\u306e\u9577\u671f\u306b\u308f\u305f\u308b\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u5185\u56e0\u6027\u30a2\u30eb\u30d6\u30df\u30f3\u3068\u5171\u6709\u7d50\u5408\u3059\u308b\u53cd\u5fdc\u6027\u306e\u85ac\u7269\u89aa\u548c\u6027\u8907\u5408\u4f53\u306e\u8a2d\u8a08\u306b\u7531\u6765\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u69cb\u9020\u7684\u7279\u5fb4\u306f\u3001\u85ac\u7269\u52d5\u614b\u3092\u89e3\u91c8\u3059\u308b\u4e0a\u3067\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>\u4eba\u53e3<\/strong><span>21 \uff5e 61 \u6b73\u306e\u5065\u5eb7\u306a\u6210\u4eba<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u30c7\u30b6\u30a4\u30f3<\/strong><span>2 \u3064\u306e\u30e9\u30f3\u30c0\u30e0\u5316\u7528\u91cf\u6f38\u5897\u8a66\u9a13<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u5e73\u5747 GH<\/strong><span>6 \u65e5\u9593\u4ee5\u4e0a\u30012 \uff5e 10 \u500d\u306b\u5897\u52a0<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u5e73\u5747 IGF-1<\/strong><span>9\uff5e11 \u65e5\u9593\u30011.5 \uff5e 3 \u500d\u306b\u5897\u52a0<\/span><\/div><div class=\"pim-evidence-row\"><strong>\u63a8\u5b9a\u534a\u6e1b\u671f<\/strong><span>5.8\u20138.1 \u65e5<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">\u30b3\u30f3\u30c6\u30ad\u30b9\u30c8\u5185\u306e\u7d50\u679c<\/h2><p class=\"wp-block-paragraph\">\u5065\u5eb7\u306a\u7537\u6027\u3092\u5bfe\u8c61\u3068\u3057\u305f\u8ffd\u8de1\u62cd\u52d5\u7814\u7a76\u3067\u306f\u3001\u9023\u7d9a\u523a\u6fc0\u4e2d\u306bGH\u30d1\u30eb\u30b9\u304c\u6301\u7d9a\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u305d\u308c\u306f\u6a5f\u69cb\u7684\u306a\u5185\u5206\u6ccc\u306e\u7814\u7a76\u3067\u3042\u308a\u3001\u8eab\u4f53\u7d44\u6210\u3084\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306e\u8a66\u9a13\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p><p class=\"wp-block-paragraph\">\u521d\u671f\u306e\u5831\u544a\u66f8\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u8a66\u9a13\u3067\u306f\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u306a\u304b\u3063\u305f\u3068\u8ff0\u3079\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u73fe\u5728\u306eFDA\u30ec\u30d3\u30e5\u30fc\u3067\u306f\u3001\u9650\u3089\u308c\u305f\u81e8\u5e8a\u30c7\u30fc\u30bf\u3068\u3001\u5fc3\u62cd\u6570\u306e\u4e0a\u6607\u3084\u5168\u8eab\u6027\u8840\u7ba1\u62e1\u5f35\u53cd\u5fdc\u306a\u3069\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306e\u5831\u544a\u304c\u7279\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p><p class=\"wp-block-paragraph\"><strong>FDA \u30bd\u30fc\u30b9\u30b9\u30b3\u30fc\u30d7:<\/strong> FDA \u30d0\u30eb\u30af \u30bb\u30fc\u30d5\u30c6\u30a3 \u30b5\u30de\u30ea\u30fc\u306b\u306f\u4e00\u822c\u7684\u306b\u300cCJC-1295\u300d\u304c\u30ea\u30b9\u30c8\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u884c\u306e DAC \u3068 DAC \u306a\u3057\u306e\u533a\u5225\u306f\u89e3\u6c7a\u3055\u308c\u307e\u305b\u3093\u3002\u30d5\u30a9\u30fc\u30e0\u56fa\u6709\u306e\u56e0\u679c\u95a2\u4fc2\u306e\u8a3c\u62e0\u3068\u3057\u3066\u5358\u72ec\u3067\u4f7f\u7528\u3059\u3079\u304d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p><h2 class=\"wp-block-heading\">\u3053\u306e\u7814\u7a76\u3067\u7b54\u3048\u3089\u308c\u306a\u3044\u3053\u3068<\/h2><p class=\"wp-block-paragraph\">\u77ed\u671f\u9593\u306e\u85ac\u529b\u5b66\u7814\u7a76\u3067\u306f\u3001\u9577\u671f\u7684\u306a\u5229\u70b9\u3084\u5b89\u5168\u6027\u306f\u78ba\u7acb\u3055\u308c\u307e\u305b\u3093\u3002<\/p><p class=\"wp-block-paragraph\">\u7d50\u679c\u3092\u300cDAC \u306a\u3057\u300d\u306e\u6750\u6599\u307e\u305f\u306f\u5206\u6790\u7684\u306b\u30ea\u30f3\u30af\u3055\u308c\u3066\u3044\u306a\u3044\u30ed\u30c3\u30c8\u306b\u8ee2\u9001\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u53e4\u5178\u7684\u306a CJC-1295 \u306e\u30d2\u30c8\u8ad6\u6587\u3067\u306f\u3001\u5065\u5eb7\u306a\u6210\u4eba\u306b\u304a\u3051\u308b\u9577\u6642\u9593\u4f5c\u7528\u578b\u30a2\u30eb\u30d6\u30df\u30f3\u7d50\u5408\u985e\u4f3c\u4f53\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u6301\u7d9a\u7684\u306a\u30db\u30eb\u30e2\u30f3\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u7814\u7a76\u5bfe\u8c61\u306e DAC \u30d5\u30a9\u30fc\u30e0\u306e\u8a3c\u62e0\u3067\u3042\u308a\u3001CJC-1295 \u306e\u540d\u524d\u3067\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u3059\u3079\u3066\u306e\u88fd\u54c1\u306e\u8a3c\u62e0\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>","protected":false},"author":1,"featured_media":643,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"322","pim_article_type":"Published study case","pim_evidence_level":"Small randomized pharmacokinetic\/pharmacodynamic human trials","pim_reviewer":"NHD evidence editorial workflow","pim_reviewed_date":"2026-08-28","pim_editorial_note":"Source-checked on 2026-08-28. Null findings and study limitations are retained. This is not independent peer review, medical advice, a customer case, or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"At least two linked primary or authoritative records and an explicit evidence boundary are present.","pim_creation_method":"The editorial workflow starts with linked peer-reviewed papers, trial registries or regulatory records; extracts the population or model, endpoints, numerical results and limitations; and separates the studied intervention from catalog material. AI-assisted drafting was used to structure the first version. Claims, figures, evidence labels and limitations were checked against the linked records in the site editorial workflow. This is not independent peer review.","pim_sources":"[{\"title\":\"CJC-1295 prolonged GH and IGF-1 stimulation in healthy adults\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16352683\/\",\"note\":\"Primary human PK\/PD study; PMID 16352683.\"},{\"title\":\"CJC-1295 and preserved GH pulsatility\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17018654\/\",\"note\":\"Mechanistic human follow-up; PMID 17018654.\"},{\"title\":\"FDA list of bulk substances with significant safety concerns\",\"url\":\"https:\/\/www.fda.gov\/drugs\/human-drug-compounding\/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks\",\"note\":\"Current CJC-1295 safety summary.\"}]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-478","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>CJC-1295 With DAC in Healthy Adults: GH, IGF-1 and Half-Life Data - NHD<\/title>\n<meta name=\"description\" content=\"The classic CJC-1295 human paper evaluated a long-acting albumin-binding analog in healthy adults. 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