{"id":474,"date":"2026-08-28T06:56:05","date_gmt":"2026-08-28T06:56:05","guid":{"rendered":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/"},"modified":"2026-08-28T07:31:46","modified_gmt":"2026-08-28T07:31:46","slug":"mots-c-2015-mitochondrial-peptide-mouse-study","status":"publish","type":"post","link":"https:\/\/nhdbio.com\/pt-br\/mots-c-2015-mitochondrial-peptide-mouse-study\/","title":{"rendered":"MOTS-c no artigo sobre metabolismo celular 2015: c\u00e9lulas, ratos e a lacuna de evid\u00eancias humanas"},"content":{"rendered":"<p class=\"pim-standfirst wp-block-paragraph\">O artigo que apresentou o MOTS-c combinou experimentos celulares com modelos metab\u00f3licos de camundongos. \u00c9 um registro de descoberta importante, mas os resultados da interven\u00e7\u00e3o foram pr\u00e9-cl\u00ednicos.<\/p><div class=\"wp-block-group pim-key-takeaways\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><h2 class=\"wp-block-heading\">O que o registro mostra<\/h2><ul class=\"wp-block-list\"><li>MOTS-c foi descrito como um pept\u00eddeo de amino\u00e1cido 16 codificado dentro do rRNA 12S mitocondrial.<\/li><li>Os autores relacionaram os efeitos celulares ao metabolismo do folato\/purina e \u00e0 ativa\u00e7\u00e3o do AMPK.<\/li><li>Os resultados da obesidade induzida pela dieta e da resist\u00eancia \u00e0 insulina vieram de ratos, e n\u00e3o de um estudo controlado de tratamento em humanos.<\/li><\/ul><\/div><\/div><figure class=\"wp-block-image size-full pim-article-figure\"><img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"http:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/mitochondrial-peptide-research-20260828.png\" alt=\"Cientista revisando imagens da membrana mitocondrial e dados de metabolismo energ\u00e9tico\" class=\"wp-image-458\" srcset=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/mitochondrial-peptide-research-20260828.png 1536w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/mitochondrial-peptide-research-20260828-300x200.png 300w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/mitochondrial-peptide-research-20260828-1024x683.png 1024w, https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/mitochondrial-peptide-research-20260828-768x512.png 768w\" sizes=\"auto, (max-width: 1536px) 100vw, 1536px\" \/><figcaption class=\"wp-element-caption\">Ilustra\u00e7\u00e3o editorial original do contexto da pesquisa. N\u00e3o \u00e9 uma figura de estudo, imagem do paciente, fotografia do produto fornecido ou representa\u00e7\u00e3o de material de estudo.<\/figcaption><\/figure><h2 class=\"wp-block-heading\">Registro de estudo<\/h2><p class=\"wp-block-paragraph\">O trabalho celular usou express\u00e3o g\u00eanica e an\u00e1lises metabol\u00f4micas para conectar MOTS-c com metabolismo de um carbono, s\u00edntese de purinas e sinaliza\u00e7\u00e3o AMPK. Esses resultados mecan\u00edsticos est\u00e3o condicionados \u00e0s c\u00e9lulas e \u00e0 exposi\u00e7\u00e3o utilizada.<\/p><div class=\"wp-block-group pim-evidence-table\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\"><div class=\"pim-evidence-row\"><strong>Descoberta<\/strong><span>Quadro de leitura aberto curto mitocondrial em rRNA 12S<\/span><\/div><div class=\"pim-evidence-row\"><strong>Comprimento do pept\u00eddeo<\/strong><span>Amino\u00e1cidos 16<\/span><\/div><div class=\"pim-evidence-row\"><strong>Sistemas experimentais<\/strong><span>C\u00e9lulas cultivadas e modelos metab\u00f3licos de camundongos<\/span><\/div><div class=\"pim-evidence-row\"><strong>Ponto final de efic\u00e1cia humana<\/strong><span>Nenhum<\/span><\/div><\/div><\/div><h2 class=\"wp-block-heading\">Resultados no contexto<\/h2><p class=\"wp-block-paragraph\">Em camundongos, o artigo relatou prote\u00e7\u00e3o contra a resist\u00eancia \u00e0 insulina associada \u00e0 idade e \u00e0 dieta rica em gordura e \u00e0 obesidade induzida pela dieta. Essas s\u00e3o observa\u00e7\u00f5es espec\u00edficas do modelo, n\u00e3o dados de resultados humanos.<\/p><p class=\"wp-block-paragraph\">Estudos humanos posteriores que medem MOTS-c circulante end\u00f3geno ou express\u00e3o relacionada ao exerc\u00edcio s\u00e3o evid\u00eancias observacionais ou fisiol\u00f3gicas; eles n\u00e3o estabelecem que a administra\u00e7\u00e3o de MOTS-c sint\u00e9tico produz benef\u00edcios.<\/p><h2 class=\"wp-block-heading\">O que este estudo n\u00e3o pode responder<\/h2><p class=\"wp-block-paragraph\">Esp\u00e9cies, via de exposi\u00e7\u00e3o e condi\u00e7\u00f5es metab\u00f3licas experimentais limitam a tradu\u00e7\u00e3o.<\/p><p class=\"wp-block-paragraph\">O artigo n\u00e3o estabelece dose cl\u00ednica, seguran\u00e7a a longo prazo ou equival\u00eancia de lote de cat\u00e1logo.<\/p>","protected":false},"excerpt":{"rendered":"<p>O artigo que apresentou o MOTS-c combinou experimentos celulares com modelos metab\u00f3licos de camundongos. \u00c9 um registro de descoberta importante, mas os resultados da interven\u00e7\u00e3o foram pr\u00e9-cl\u00ednicos.<\/p>","protected":false},"author":1,"featured_media":639,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"pim_family_ids":"352","pim_article_type":"Published study case","pim_evidence_level":"Mechanistic cell work and mouse models; no therapeutic human trial","pim_reviewer":"NHD evidence editorial workflow","pim_reviewed_date":"2026-08-28","pim_editorial_note":"Source-checked on 2026-08-28. Null findings and study limitations are retained. This is not independent peer review, medical advice, a customer case, or validation of a catalog lot.","pim_review_status":"reviewed","pim_review_reason":"At least two linked primary or authoritative records and an explicit evidence boundary are present.","pim_creation_method":"The editorial workflow starts with linked peer-reviewed papers, trial registries or regulatory records; extracts the population or model, endpoints, numerical results and limitations; and separates the studied intervention from catalog material. AI-assisted drafting was used to structure the first version. Claims, figures, evidence labels and limitations were checked against the linked records in the site editorial workflow. This is not independent peer review.","pim_sources":"[{\"title\":\"MOTS-c discovery and metabolic mouse study\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25738453\/\",\"note\":\"Primary 2015 paper; PMID 25738453.\"},{\"title\":\"Review of mitochondrial-derived peptides in energy metabolism\",\"url\":\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32776825\/\",\"note\":\"Evidence-context review; PMID 32776825.\"},{\"title\":\"FDA list of bulk substances with significant safety concerns\",\"url\":\"https:\/\/www.fda.gov\/drugs\/human-drug-compounding\/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks\",\"note\":\"Current FDA MOTS-c summary.\"}]","footnotes":""},"categories":[19],"tags":[],"class_list":["post-474","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-published-study-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap - NHD<\/title>\n<meta name=\"description\" content=\"The paper that introduced MOTS-c combined cell experiments with mouse metabolic models. It is an important discovery record, but the intervention findings\u2026\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nhdbio.com\/pt-br\/mots-c-2015-mitochondrial-peptide-mouse-study\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap\" \/>\n<meta property=\"og:description\" content=\"The paper that introduced MOTS-c combined cell experiments with mouse metabolic models. It is an important discovery record, but the intervention findings\u2026\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nhdbio.com\/pt-br\/mots-c-2015-mitochondrial-peptide-mouse-study\/\" \/>\n<meta property=\"og:site_name\" content=\"NHD\" \/>\n<meta property=\"article:published_time\" content=\"2026-08-28T06:56:05+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-08-28T07:31:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1536\" \/>\n\t<meta property=\"og:image:height\" content=\"960\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/webp\" \/>\n<meta name=\"author\" content=\"NHD Technical Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:description\" content=\"Peptide Raw Materials and Custom Peptide Synthesis\" \/>\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"NHD Technical Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. tempo de leitura\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/\"},\"author\":{\"name\":\"NHD Technical Team\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#\\\/schema\\\/person\\\/0ffb0dec7fda0f720073fc468fac6fc1\"},\"headline\":\"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap\",\"datePublished\":\"2026-08-28T06:56:05+00:00\",\"dateModified\":\"2026-08-28T07:31:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/\"},\"wordCount\":236,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/generated-news\\\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp\",\"articleSection\":[\"Published Study Reviews\"],\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/\",\"url\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/\",\"name\":\"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap - NHD\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/generated-news\\\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp\",\"datePublished\":\"2026-08-28T06:56:05+00:00\",\"dateModified\":\"2026-08-28T07:31:46+00:00\",\"description\":\"The paper that introduced MOTS-c combined cell experiments with mouse metabolic models. It is an important discovery record, but the intervention findings\u2026\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#breadcrumb\"},\"inLanguage\":\"pt-BR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#primaryimage\",\"url\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/generated-news\\\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp\",\"contentUrl\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/08\\\/generated-news\\\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp\",\"width\":1536,\"height\":960,\"caption\":\"Article-specific editorial image.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/mots-c-2015-mitochondrial-peptide-mouse-study\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/nhdbio.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#website\",\"url\":\"https:\\\/\\\/nhdbio.com\\\/\",\"name\":\"NHD\",\"description\":\"Peptide Raw Materials and Custom Peptide Synthesis\",\"publisher\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/nhdbio.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"pt-BR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#organization\",\"name\":\"NHD\",\"url\":\"https:\\\/\\\/nhdbio.com\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/codex-clipboard-354c928e-4b5b-482d-9261-02023d4c9680.png\",\"contentUrl\":\"https:\\\/\\\/nhdbio.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/codex-clipboard-354c928e-4b5b-482d-9261-02023d4c9680.png\",\"width\":2172,\"height\":724,\"caption\":\"NHD\"},\"image\":{\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/nhdbio.com\\\/#\\\/schema\\\/person\\\/0ffb0dec7fda0f720073fc468fac6fc1\",\"name\":\"NHD Technical Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"pt-BR\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g\",\"caption\":\"NHD Technical Team\"},\"description\":\"NHD Technical Team maintains research-use catalog documentation and evidence summaries. Reviewed articles link to peer-reviewed papers, trial registries and regulatory records, retain null findings and study limitations, and distinguish published interventions from catalog materials. AI-assisted drafting may be used for structure; source links and evidence boundaries remain visible. This work is not independent peer review or medical advice.\",\"sameAs\":[\"https:\\\/\\\/nhdbio.com\"],\"url\":\"https:\\\/\\\/nhdbio.com\\\/pt-br\\\/author\\\/qianmiao-technical-team\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"MOTS-c no artigo sobre metabolismo celular 2015: c\u00e9lulas, ratos e a lacuna de evid\u00eancias humanas - NHD","description":"O artigo que apresentou o MOTS-c combinou experimentos celulares com modelos metab\u00f3licos de camundongos. \u00c9 um registro de descoberta importante, mas os resultados da interven\u00e7\u00e3o\u2026","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/nhdbio.com\/pt-br\/mots-c-2015-mitochondrial-peptide-mouse-study\/","og_locale":"pt_BR","og_type":"article","og_title":"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap","og_description":"The paper that introduced MOTS-c combined cell experiments with mouse metabolic models. It is an important discovery record, but the intervention findings\u2026","og_url":"https:\/\/nhdbio.com\/pt-br\/mots-c-2015-mitochondrial-peptide-mouse-study\/","og_site_name":"NHD","article_published_time":"2026-08-28T06:56:05+00:00","article_modified_time":"2026-08-28T07:31:46+00:00","og_image":[{"width":1536,"height":960,"url":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp","type":"image\/webp"}],"author":"NHD Technical Team","twitter_card":"summary_large_image","twitter_description":"Peptide Raw Materials and Custom Peptide Synthesis","twitter_misc":{"Escrito por":"NHD Technical Team","Est. tempo de leitura":"1 minuto"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#article","isPartOf":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/"},"author":{"name":"NHD Technical Team","@id":"https:\/\/nhdbio.com\/#\/schema\/person\/0ffb0dec7fda0f720073fc468fac6fc1"},"headline":"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap","datePublished":"2026-08-28T06:56:05+00:00","dateModified":"2026-08-28T07:31:46+00:00","mainEntityOfPage":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/"},"wordCount":236,"commentCount":0,"publisher":{"@id":"https:\/\/nhdbio.com\/#organization"},"image":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#primaryimage"},"thumbnailUrl":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp","articleSection":["Published Study Reviews"],"inLanguage":"pt-BR","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/","url":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/","name":"MOTS-c no artigo sobre metabolismo celular 2015: c\u00e9lulas, ratos e a lacuna de evid\u00eancias humanas - NHD","isPartOf":{"@id":"https:\/\/nhdbio.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#primaryimage"},"image":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#primaryimage"},"thumbnailUrl":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp","datePublished":"2026-08-28T06:56:05+00:00","dateModified":"2026-08-28T07:31:46+00:00","description":"O artigo que apresentou o MOTS-c combinou experimentos celulares com modelos metab\u00f3licos de camundongos. \u00c9 um registro de descoberta importante, mas os resultados da interven\u00e7\u00e3o\u2026","breadcrumb":{"@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#breadcrumb"},"inLanguage":"pt-BR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/"]}]},{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#primaryimage","url":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp","contentUrl":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/08\/generated-news\/mots-c-2015-mitochondrial-peptide-mouse-study-featured-v2.webp","width":1536,"height":960,"caption":"Article-specific editorial image."},{"@type":"BreadcrumbList","@id":"https:\/\/nhdbio.com\/mots-c-2015-mitochondrial-peptide-mouse-study\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/nhdbio.com\/"},{"@type":"ListItem","position":2,"name":"MOTS-c in the 2015 Cell Metabolism Paper: Cells, Mice and the Human Evidence Gap"}]},{"@type":"WebSite","@id":"https:\/\/nhdbio.com\/#website","url":"https:\/\/nhdbio.com\/","name":"NHD","description":"Mat\u00e9rias-primas pept\u00eddicas e s\u00edntese personalizada","publisher":{"@id":"https:\/\/nhdbio.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/nhdbio.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"pt-BR"},{"@type":"Organization","@id":"https:\/\/nhdbio.com\/#organization","name":"NHD","url":"https:\/\/nhdbio.com\/","logo":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/nhdbio.com\/#\/schema\/logo\/image\/","url":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/codex-clipboard-354c928e-4b5b-482d-9261-02023d4c9680.png","contentUrl":"https:\/\/nhdbio.com\/wp-content\/uploads\/2026\/09\/codex-clipboard-354c928e-4b5b-482d-9261-02023d4c9680.png","width":2172,"height":724,"caption":"NHD"},"image":{"@id":"https:\/\/nhdbio.com\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/nhdbio.com\/#\/schema\/person\/0ffb0dec7fda0f720073fc468fac6fc1","name":"Equipe T\u00e9cnica NHD","image":{"@type":"ImageObject","inLanguage":"pt-BR","@id":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/8445618b3e2834fa0c7ae1a03a371ed002e9bf8d2cc1cd989dc4a71bb2b66110?s=96&d=mm&r=g","caption":"NHD Technical Team"},"description":"A equipe t\u00e9cnica NHD mant\u00e9m documenta\u00e7\u00e3o de cat\u00e1logo de uso em pesquisa e resumos de evid\u00eancias. Os artigos revisados \u200b\u200bvinculam-se a artigos revisados \u200b\u200bpor pares, registros de ensaios e registros regulat\u00f3rios, ret\u00eam resultados nulos e limita\u00e7\u00f5es de estudos e distinguem interven\u00e7\u00f5es publicadas de materiais de cat\u00e1logo. O desenho assistido por AI pode ser usado para estrutura; os links de origem e os limites das evid\u00eancias permanecem vis\u00edveis. Este trabalho n\u00e3o \u00e9 uma revis\u00e3o independente por pares ou aconselhamento m\u00e9dico.","sameAs":["https:\/\/nhdbio.com"],"url":"https:\/\/nhdbio.com\/pt-br\/author\/qianmiao-technical-team\/"}]}},"_links":{"self":[{"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/posts\/474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/comments?post=474"}],"version-history":[{"count":1,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/posts\/474\/revisions"}],"predecessor-version":[{"id":502,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/posts\/474\/revisions\/502"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/media\/639"}],"wp:attachment":[{"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/media?parent=474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/categories?post=474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nhdbio.com\/pt-br\/wp-json\/wp\/v2\/tags?post=474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}