Custom Peptide Synthesis for Scientific Research
Custom peptide project enquiries with sequence, modification, scale, analytical and documentation requirements reviewed before quotation.
NHD accepts custom peptide project enquiries for research and manufacturing use. Sequence, modification, scale and target specification are reviewed before feasibility, source and production arrangements are confirmed.
Analytical methods, release criteria, manufacturing responsibility and document availability are defined in the written quotation for each project; they are not assumed from catalog-wide claims.
Synthesis Capabilities
Sequence length, composition, modification, scale and analytical requirements determine feasibility. Common request types include:
- Standard peptides — sequence, termini, counterion, target scale and delivery form must be stated.
- Modified peptides — acetylation, amidation, phosphorylation, biotinylation, PEGylation and non-natural residues may be reviewed.
- Cyclic & constrained — cyclization route and disulfide connectivity require project-specific confirmation.
- Difficult sequences — hydrophobicity, aggregation, length and modification burden are assessed before feasibility is accepted.
Purity Grades & Scale
The purity method, acceptance limit and assay need should be defined together. A target percentage alone does not establish identity, content or suitability.
- Method development — define whether a partially purified material is acceptable for the intended analytical question.
- Higher-purity requests — define the HPLC method, detection conditions, impurity concern and acceptance limit.
- Project-specific target — define the analytical method, acceptance limit and downstream need in the written specification.
Project-Specific Quality Control
Identity, purity and any additional analytical requirements must be agreed in the project specification. Available methods and documents are confirmed before work begins.
- Chromatography — method, detector, integration rule and acceptance limit must be defined.
- Mass spectrometry — instrument approach and acceptance criteria must be appropriate to the analyte.
- Additional requests — content, counterion, water, residual-solvent or endotoxin scope is confirmed where relevant and available.
Service Specifications
| Parameter | Specification |
|---|---|
| Synthesis approach | Confirmed after sequence and modification review |
| Length | Reviewed per sequence; no catalog-wide maximum claimed |
| Scale | Confirmed after feasibility and supply-responsibility review |
| Purity target | Defined in the accepted project specification |
| Analytical scope | Methods confirmed in the quotation |
| Turnaround | Confirmed after sequence and modification review |
| Deliverable | Defined by the accepted specification and document list |
Frequently Asked Questions
What turnaround time should I expect?
Lead time depends on sequence, scale, modification, analytical scope and manufacturing arrangement. It is confirmed in the written quotation.
Which purity grade do I need for cell-based assays?
The appropriate specification depends on the assay, impurity risk and quantitation method. State the intended analytical need and request the actual release specification rather than relying on a catalog-wide purity claim.
Can you remove residual TFA from synthesis?
Counterion requirements should be stated with the requested analytical method and acceptance limit. Feasibility and the final reported form are confirmed in the quotation.
Request a Custom Peptide Quote
Submit the sequence, target scale, purity grade and modifications for feasibility, pricing and lead-time review. Contact our team to get started.