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Research Supplies & Solvents · Source-reviewed dossier

Acetic Acid Solution

Source-Reviewed Research Dossier

Acetic acid solution is a laboratory solvent used to adjust acidity and help some peptides dissolve. Whether it works depends on the peptide, concentration and other ingredients. One microneedle-coating study used acetic acid together with water and another solvent to dissolve peptides while preserving the activity measured. That result describes the complete mixture, not acetic acid alone. Before using a research solution in an experiment, check its actual concentration and test whether it is compatible with the target material.

Research use only Lot documents on request
Acetic Acid Solution research product family with 2 catalog variants
AI-generated packaging mockup for catalog navigation. It is not a photograph of an actual supplied lot; container, label and presentation may vary.

Product family

Compound overview

Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.

Product identity

Product type
Research solution or laboratory supply
Catalog family
Acetic Acid Solution
Research category
Research Supplies & Solvents
Catalog CAS RN
64-19-7
Catalog molecular formula
C2H4O2
Catalog molecular weight
60.05 g/mol
Identity boundary
The listed CAS, formula and molecular weight describe acetic acid, not the complete aqueous formulation or its concentration.
Evidence status
Authoritative chemical identity plus formulation-specific laboratory evidence
Intended use
Research, development and manufacturing use only

Literature reference parameters

Compound or material class
Dilute acetic-acid laboratory solventCatalog-family identity
Evidence scope
Authoritative chemical identity plus formulation-specific laboratory evidenceDo not generalize beyond the cited model
Source review
Primary or authoritative records linked belowChecked 2026-09-01

Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.

Mechanism of action

How Acetic Acid Solution is studied

A target-to-pathway view grounded in the linked research records.

What an acidic co-solvent does

Acetic acid is a weak organic acid. Mixed into water, it raises acidity and changes which parts of a dissolved molecule carry an electric charge. That can help some peptides dissolve or stay in solution. It is not a universal effect: each peptide behaves differently, and the result depends on concentration and the surrounding liquid. A catalog acetic acid solution is therefore a testing starting point, not a fixed recipe that works the same way for every research peptide.

The microneedle coating study

A published formulation study used water, 2-methyl-2-butanol and acetic acid together to dissolve peptide autoantigens for coating onto metal microneedles. The three-solvent mixture dissolved both water-loving and water-avoiding peptides, and the process did not damage the peptides' biological activity. Surface preparation and coating thickness also changed how much peptide reached skin. Acetic acid was one part of that exact mixture, so the finding supports that formulation design, not acetic acid used alone.

What this means for the catalog product

PubChem documents the identity of acetic acid, but identity alone does not describe a diluted aqueous catalog solution. Concentration, acidity and storage must be read from the current product specification. Even then, whether the solution suits a given peptide and procedure must be tested. Compatibility, stability and sterility cannot be assumed from the neat chemical record. Treat the vial as a research supply to be checked in your own system, and keep any published formulation result attached to the study model and mixture where it was seen.

Reported research findings

What published studies report about Acetic Acid Solution

Reported outcomes are paired with their experimental model and evidence boundary.

Authoritative database

Chemical identity is well defined

PubChem lists acetic acid as CAS 64-19-7, molecular formula C2H4O2 and molecular weight 60.05 g/mol.

Compound identity does not state the concentration or release specification of this catalog solution.

Read the primary study
Formulation study

Acetic acid was one part of a peptide co-solvent system

A coated-microneedle formulation study used water, 2-methyl-2-butanol and acetic acid to dissolve hydrophilic and hydrophobic peptide antigens.

PMID 28286315 evaluated a specific multi-component formulation; it is not a general reconstitution rule.

Read the primary study
Translation boundary: findings are limited to the evidence level stated on each card. Experimental protocol quantities are research details, not usage instructions.

Catalog options

Variant specifications

Pack-level catalog data; lot-level controls remain document-specific.

Catalog no.AA3
Pack size3 ml × 10 vials
Specification & documents for AA3

Product specification

Laboratory research solution · 3 ml/vial nominal fill · 10-vial pack · concentration, formulation and fill volume controlled by lot specification.

Lot documentation

Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.

Catalog no.AA10
Pack size10 ml × 10 vials
Specification & documents for AA10

Product specification

Laboratory research solution · 10 ml/vial nominal fill · 10-vial pack · concentration, formulation and fill volume controlled by lot specification.

Lot documentation

Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.

Quality system

Quality documentation

A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.

Lot-specific Certificate of AnalysisAvailability and scope must be confirmed for the selected catalog variant and lot
COA availability unconfirmed Ask about availability
Product Specification SheetAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Analytical Method SummaryAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request

Analytical interpretation

Interpret the documents, not just the headline number.

Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.

Open the Quality & Documentation Hub

HPLC area ≠ assayA dominant peak does not establish target mass fraction.

Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.

Counterions affect contentWater, salt form and solvents change the as-is composition.

Storage needs a data basisShipping practice is not the same as stability evidence.

Evidence map

Research context

Published studies and regulatory records, not customer testimonials or usage guidance.

Authoritative database

Chemical identity is well defined

Compound identity does not state the concentration or release specification of this catalog solution.

View primary record
Formulation study

Acetic acid was one part of a peptide co-solvent system

PMID 28286315 evaluated a specific multi-component formulation; it is not a general reconstitution rule.

View primary record
Evidence boundary: each card states its evidence type. Human trials and regulatory records describe the studied or regulated intervention; preclinical records remain model-specific. None verifies the identity, quality, safety or efficacy of this catalog lot or provides usage instructions.

Literature basis

Curated references

Third-party publications selected for direct relevance.

  1. 01

    PubChem Compound Summary: Acetic Acid

    National Library of Medicine. PubChem CID 176; updated compound record.

    Authoritative identity
  2. 02

    Formulation of hydrophobic peptides for skin delivery via coated microneedles

    Chen X, et al. Journal of Controlled Release. 2017. PMID 28286315.

    Formulation study

Research FAQ

Acetic Acid Solution questions

Concise answers for researchers comparing identity, evidence and catalog variants.

What effects are studied for Acetic Acid Solution?

It serves as a laboratory solvent and formulation component, usually when a researcher needs to change acidity or help a peptide dissolve. The clearest published example is a microneedle coating study where it was one of three solvents that dissolved both water-loving and water-avoiding peptides without harming their activity. That finding belongs to that specific mixture and process.

How should the Acetic Acid Solution research findings be understood?

PubChem documents the identity of acetic acid, but identity alone does not describe a diluted aqueous catalog solution. Concentration, acidity and storage must be read from the current product specification. Even then, whether the solution suits a given peptide and procedure must be tested. Compatibility, stability and sterility cannot be assumed from the neat chemical record. Treat the vial as a research supply to be checked in your own system, and keep any published formulation result attached to the study model and mixture where it was seen.

What evidence is available for Acetic Acid Solution?

The public evidence supports acetic-acid identity and shows that acetic acid can be one component of a tested peptide formulation. A product-specific specification is still required.

Does the cited research validate this catalog material?

No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.

Which quality documents can be requested?

A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.

How should Acetic Acid Solution be stored?

Store at 2-8 °C. Do not freeze. Protect from light. Confirm the applicable storage statement on the product-specific specification and lot documentation.

Knowledge tools

Continue with structured evidence

Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.

Internal technical source review

Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.

Editorial status: NHD evidence editorial workflow · 2026-09-01 · Not independent medical review · Review policy

Technical procurement

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Selected: AA3 · 3 ml × 10 vials