NHD Global
Growth Hormone & IGF · Source-reviewed dossier
Source-Reviewed Research Dossier
Hexarelin acetate is a synthetic peptide studied for its effects on growth-hormone release and, separately, on the heart and blood vessels. It acts like ghrelin, the body's natural signal, by switching on the same receptor. There is also a hypothesis that it interacts with CD36, a protein on heart cells, without involving growth hormone. However, most heart-related evidence comes from mechanistic or animal experiments, not controlled human outcome studies. A review describes hypotheses rather than confirmed clinical benefit. This catalog material is intended for laboratory research only, not for human use.
Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.
Product identity
Literature reference parameters
Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.
A target-to-pathway view grounded in the linked research records.
Reported research findings
Reported outcomes are paired with their experimental model and evidence boundary.
A focused review describes GH-dependent and GH-independent cardiovascular hypotheses for hexarelin.
Review-level mechanisms do not establish clinical efficacy.
Read the primary studyA 2023 study reported apoptosis-related outcomes in an ischemic acute-kidney-injury model.
The experiment does not support human treatment or catalog-lot claims.
Read the primary studyCatalog options
Pack-level catalog data; lot-level controls remain document-specific.
Single-component peptide · 2 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
Single-component peptide · 5 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.
Analytical interpretation
Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.
Open the Quality & Documentation HubHPLC area ≠ assayA dominant peak does not establish target mass fraction.
Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.
Counterions affect contentWater, salt form and solvents change the as-is composition.
Storage needs a data basisShipping practice is not the same as stability evidence.
Evidence map
Published studies and regulatory records, not customer testimonials or usage guidance.
Review-level mechanisms do not establish clinical efficacy.
View primary recordThe experiment does not support human treatment or catalog-lot claims.
View primary recordThird-party publications selected for direct relevance.
Mao Y, et al. Journal of Geriatric Cardiology. 2014. PMID 25278975.
Preclinical study. 2023. PMID 37710348.
Concise answers for researchers comparing identity, evidence and catalog variants.
The clearest action is activation of the ghrelin receptor, which leads to growth-hormone release. Researchers have also proposed a second route involving CD36 on heart cells that could act without growth hormone. That cardiac idea comes mainly from mechanistic and animal experiments, not controlled human outcome studies, so it should be read as a research hypothesis rather than a demonstrated effect in people.
The strongest supported statements are receptor activity and preclinical observations. A focused review summarizes cardiovascular hypotheses from mixed evidence, and the kidney work is animal and cell based. No controlled human outcome trial is cited here. So claims about cardiac protection in people, or about any research material producing a particular biological result, go beyond what the supplied records show. Identity and lot quality are separate analytical matters, not evidence of effect.
The public evidence is dominated by reviews and preclinical cardiovascular or renal models.
No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.
A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.
Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.
Knowledge center
Owned educational content connected to this family.
Hexarelin has controlled human pharmacology data, but the central evidence is an acute 12-person GH dose-response experiment rather than a clinical-outcome trial.
Updated October 1, 2026
Hexarelin, also called Examorelin, is an amidated synthetic hexapeptide. The 2-methyl substitution on D-tryptophan distinguishes it from related GHRPs.
Updated October 1, 2026
An early human experiment measured a brief change in ejection fraction. Understand the result without turning it into a heart-treatment claim.
Updated October 10, 2026Knowledge tools
Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.
Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.
Technical procurement
Selected: HX2 · 2 mg × 10 vials
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