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西安诺和达生物科技有限公司
For research, development and manufacturing use only. Not for human or veterinary use.

Healing & Tissue Repair · Source-reviewed dossier

KPV

Source-Reviewed Research Dossier

KPV is a short three-amino-acid peptide, named for lysine, proline and valine. Research has examined inflammatory signaling in cells and experimental intestinal inflammation in animals. Some studies deliver KPV using a carrier, such as nanoparticles or a hydrogel; that carrier is part of the experiment. This page explains the findings in plain language, separates free-peptide and delivery-system results, and lists the identity and variants relevant to a research quotation.

Research use only Lot documents on request
KPV research product family with 2 catalog variants
AI-generated packaging mockup for catalog navigation. It is not a photograph of an actual supplied lot; container, label and presentation may vary.

Product family

Compound overview

Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.

Product identity

Product type
Peptide research compound
Catalog family
KPV
Research category
Healing & Tissue Repair
Catalog CAS RN
67727-97-3
Catalog molecular formula
C16H30N4O4
Catalog molecular weight
342.44 g/mol
Catalog sequence
Lys-Pro-Val
Evidence status
Cell and animal research; no established controlled human efficacy
Intended use
Research, development and manufacturing use only

Literature reference parameters

Compound or material class
α-MSH-derived Lys-Pro-Val tripeptideCatalog-family identity
Evidence scope
Cell and animal research; no established controlled human efficacyDo not generalize beyond the cited model
Source review
Primary or authoritative records linked belowChecked 2026-09-01

Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.

Mechanism of action

How KPV is studied

A target-to-pathway view grounded in the linked research records.

Calming inflammation in skin cells

In human skin cells exposed to fine dust, KPV reduced oxidative stress and lowered release of IL-1 beta, an inflammatory messenger. It also limited signs of programmed cell death. These are cell-dish findings. They do not show that KPV protects skin in living animals or people.

Gut inflammation in mice with special delivery

One mouse study gave KPV inside nanoparticles wrapped in a gel designed to release it in the colon. This system reduced gut inflammation in mice with experimental colitis. The benefit belongs to the nanoparticle-gel plus KPV, not to KPV alone. The result is from mice and does not apply to humans.

Evidence limits and material identity

The findings listed here come from cells or mice. The linked studies do not establish controlled human treatment benefits. Catalog KPV is for research use only. Its identity and purity are set by the product specification and lot documents, not by biological results. A vial is not a medicine and has no proven health benefit.

Reported research findings

What published studies report about KPV

Reported outcomes are paired with their experimental model and evidence boundary.

Cell study

Keratinocyte stress pathways were evaluated

A 2025 study reported reduced apoptosis and inflammatory signaling in a fine-dust-exposed keratinocyte model.

In-vitro exposure cannot establish topical or systemic human outcomes.

Read the primary study
Mouse colitis model

Targeted delivery was studied in experimental colitis

KPV-loaded nanoparticles in a polysaccharide hydrogel were evaluated in a mouse colitis model.

The delivery system and animal model are integral to the result.

Read the primary study
Translation boundary: findings are limited to the evidence level stated on each card. Experimental protocol quantities are research details, not usage instructions.

Catalog options

Variant specifications

Pack-level catalog data; lot-level controls remain document-specific.

Catalog no.KPV5
Pack size5 mg × 10 vials
Specification & documents for KPV5

Product specification

Single-component peptide · 5 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.

Lot documentation

Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.

Catalog no.KPV10
Pack size10 mg × 10 vials
Specification & documents for KPV10

Product specification

Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.

Lot documentation

Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.

Quality system

Quality documentation

A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.

Lot-specific Certificate of AnalysisAvailability and scope must be confirmed for the selected catalog variant and lot
COA availability unconfirmed Ask about availability
Product Specification SheetAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Analytical Method SummaryAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request

Analytical interpretation

Interpret the documents, not just the headline number.

Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.

Open the Quality & Documentation Hub

HPLC area ≠ assayA dominant peak does not establish target mass fraction.

Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.

Counterions affect contentWater, salt form and solvents change the as-is composition.

Storage needs a data basisShipping practice is not the same as stability evidence.

Evidence map

Research context

Published studies and regulatory records, not customer testimonials or usage guidance.

Cell study

Keratinocyte stress pathways were evaluated

In-vitro exposure cannot establish topical or systemic human outcomes.

View primary record
Mouse colitis model

Targeted delivery was studied in experimental colitis

The delivery system and animal model are integral to the result.

View primary record
Evidence boundary: each card states its evidence type. Human trials and regulatory records describe the studied or regulated intervention; preclinical records remain model-specific. None verifies the identity, quality, safety or efficacy of this catalog lot or provides usage instructions.

Literature basis

Curated references

Third-party publications selected for direct relevance.

  1. 01 Cell study
  2. 02

    Drug-loaded nanoparticles targeted to the colon reduce colitis in mice

    Laroui H, et al. Gastroenterology. 2010. PMID 19909746.

    Mouse colitis model

Research FAQ

KPV questions

Concise answers for researchers comparing identity, evidence and catalog variants.

What effects are studied for KPV?

In human skin cells exposed to fine dust, KPV reduced oxidative stress, lowered IL-1 beta, and limited cell-death signals. In a mouse colitis model, KPV delivered in nanoparticles and a gel reduced gut damage. These are lab and animal findings only. They do not prove KPV treats skin damage, colitis, or any condition in people.

How should the KPV research findings be understood?

The findings listed here come from cells or mice. The linked studies do not establish controlled human treatment benefits. Catalog KPV is for research use only. Its identity and purity are set by the product specification and lot documents, not by biological results. A vial is not a medicine and has no proven health benefit.

What evidence is available for KPV?

The available evidence includes cell work and targeted-delivery animal studies rather than controlled human trials.

Does the cited research validate this catalog material?

No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.

Which quality documents can be requested?

Tell us which records your project requires. Availability and scope must be confirmed for the selected material. Published papers are not batch certificates, and this page does not confirm that a lot-specific COA is available.

How should KPV be stored?

Request the storage conditions for the exact supplied form and selected variant. A temperature stated for another supplier or a clinical drug preparation is not a verified storage specification for NHD catalog material.

Does a KPV-loaded carrier study also test free KPV?

Not necessarily. The study design must say which groups were compared. A carrier can affect where and how much material reaches the tested tissue, so the combination should not be treated as equivalent to an unformulated research vial.

What should I include in a research quotation request?

Send the exact product name, selected catalog variant, required quantity, destination and documents needed for the project. Specify whether the amount refers to powder mass or measured peptide content. Availability, price, lead time and document scope require confirmation.

Does a published study replace a lot-specific analytical report?

No. A paper describes the material and methods used in that study. It does not establish the identity, purity or content of a different supplied lot. Ask which records actually apply to the requested material; do not assume a COA is available.

Knowledge center

Related insights

Owned educational content connected to this family.

Editorial comic illustration: Understanding KPV. Conceptual cover, not experimental imagery.

What is KPV? A simple research buying guide

KPV is a short peptide made from three amino acids. Its name is an abbreviation: K means lysine, P means proline and V means…

Updated October 3, 2026
Editorial comic illustration: KPV & Cell Entry. Conceptual cover, not experimental imagery.

KPV and gut inflammation: why getting into the cell matters

KPV is a three-amino-acid peptide. Researchers examined whether a transport pathway called PepT1 helped it enter cells and affect inflammatory signaling. This guide explains…

Updated October 9, 2026

Knowledge tools

Continue with structured evidence

Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.

Internal technical source review

Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.

Editorial status: NHD evidence editorial workflow · 2026-10-09 · Not independent medical review · Review policy

Technical procurement

Ready to request a quote?

Selected: KPV5 · 5 mg × 10 vials