NHD Global
Reproductive & Hormone · Source-reviewed dossier
Source-Reviewed Research Dossier
PT-141 (bremelanotide) is a lab-made peptide. It activates melanocortin receptors, a family of signaling proteins involved in appetite, skin and hair pigmentation, and sexual behavior. Researchers studied it as a non-hormonal way to affect sexual desire pathways in the brain, rather than blood flow or testosterone. The clearest human evidence is a small early placebo-controlled trial. In premenopausal women with sexual arousal disorder, a single intranasal dose led to more women reporting moderate-to-high desire. A trend toward better genital arousal and greater satisfaction appeared among those who had intercourse. Vaginal blood flow during erotic videos did not change significantly. Approved medicine and research powder are different things.
Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.
Product identity
Literature reference parameters
Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.
A target-to-pathway view grounded in the linked research records.
Reported research findings
Reported outcomes are paired with their experimental model and evidence boundary.
The U.S. label defines a 1.75 mg autoinjector and indication for selected premenopausal women with acquired, generalized HSDD.
The label does not approve catalog PT-141 material or other routes/populations.
Read the primary studyA placebo-controlled study evaluated intranasal bremelanotide in premenopausal women with sexual arousal disorder.
The study population and intranasal formulation do not establish outcomes for catalog powder or the approved autoinjector.
Read the primary studyCatalog options
Pack-level catalog data; lot-level controls remain document-specific.
Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.
Analytical interpretation
Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.
Open the Quality & Documentation HubHPLC area ≠ assayA dominant peak does not establish target mass fraction.
Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.
Counterions affect contentWater, salt form and solvents change the as-is composition.
Storage needs a data basisShipping practice is not the same as stability evidence.
Evidence map
Published studies and regulatory records, not customer testimonials or usage guidance.
The label does not approve catalog PT-141 material or other routes/populations.
View primary recordThe study population and intranasal formulation do not establish outcomes for catalog powder or the approved autoinjector.
View primary recordThird-party publications selected for direct relevance.
DailyMed/FDA label.
Randomized controlled trial. 2006. PMID 16839319.
Concise answers for researchers comparing identity, evidence and catalog variants.
In a placebo-controlled trial of premenopausal women with sexual arousal disorder, a single intranasal dose led more women to report moderate-to-high sexual desire. A trend toward more positive feelings of genital arousal appeared, and those who attempted intercourse within a day were more satisfied with their arousal. Vaginal blood flow during erotic videos did not change significantly. These are short-term subjective findings from a small early study in one population, using one route.
Bremelanotide findings depend on the exact formulation and route. The human study used one intranasal dose in premenopausal women. The approved autoinjector uses a different route, fixed dose, and defined population with contraindications. Neither the trial formulation nor the approved product tells us how catalog powder, other routes, or different groups would behave. Catalog material is handled under its specification and lot documentation, not as the finished medicine. This boundary defines which claims a given material and study can actually support.
Human pharmacology and product-specific regulatory evidence exist, with strict indication and safety boundaries.
No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.
A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.
Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.
Knowledge center
Owned educational content connected to this family.
Bremelanotide has a real FDA-approved finished-drug record, but its scope is narrow. The RECONNECT trials studied premenopausal women with acquired, generalized HSDD—not men, performance…
Updated October 1, 2026
PT-141 is the development code associated with bremelanotide. A free-base peptide, its acetate form and the approved finished injection are related records, but they…
Updated October 1, 2026Knowledge tools
Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.
Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.
Technical procurement
Selected: P41 · 10 mg × 10 vials
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