Cosmetic & Skin · Source-reviewed dossier
SNAP-8
Source-Reviewed Research Dossier
SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide used in topical anti-wrinkle formulations. The cited human studies tested multi-ingredient microneedle patches, so improvements cannot be attributed to acetyl octapeptide-3 alone.
Compound overview
Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; the current product specification and lot COA control.
Product identity
- Product type
- Peptide research compound
- Catalog family
- SNAP-8
- Research category
- Cosmetic & Skin
- Catalog CAS RN
- 868844-74-0
- Catalog molecular formula
- C43H68N14O16S
- Catalog molecular weight
- 1075.15 g/mol
- Catalog sequence
- Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Acetyl Octapeptide-3)
- Evidence status
- Combination-formula topical/microneedle evidence; standalone contribution is not isolated
- Intended use
- Research, development and manufacturing use only
Literature reference parameters
- Compound or material class
- Acetyl octapeptide-3 cosmetic peptideCatalog-family identity
- Evidence scope
- Combination-formula topical/microneedle evidence; standalone contribution is not isolatedDo not generalize beyond the cited model
- Source review
- Primary or authoritative records linked belowChecked 2026-09-01
Identity safeguard Reference identifiers above describe the literature compound record. The supplied form, formula, molecular weight, purity and storage conditions must be verified against the product-specific specification and lot COA.
How SNAP-8 is studied
A target-to-pathway view grounded in the linked research records.
Reported research findings
What published studies report about SNAP-8
Reported outcomes are paired with their experimental model and evidence boundary.
A multi-ingredient microneedle patch improved measured eye-area outcomes
The patch contained acetyl octapeptide-3, hyaluronic acid, vitamin-C derivative and cyclic lysophosphatidic acid; 24 healthy subjects were followed for 28 days.
Because several active components and a microneedle device were used, SNAP-8’s independent contribution was not isolated.
Read the primary studyWrinkle measures changed with a multi-ingredient patch regimen
A 12-week clinical study evaluated a dissolving microneedle patch containing acetyl octapeptide-3 with other cosmetic ingredients.
The design supports the tested combination only, not standalone acetyl octapeptide-3.
Read the primary studyCatalog options
Variant specifications
Pack-level catalog data; lot-level controls remain document-specific.
Specification & documents for NP810
Product specification
Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Lot documentation
Request by lot: CoA, HPLC purity and MS identity
Quality documentation
Document availability is stated honestly and can vary by catalog variant or lot.
Analytical interpretation
Interpret the documents, not just the headline number.
Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.
Open the Quality & Documentation HubHPLC area ≠ assayA dominant peak does not establish target mass fraction.
Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.
Counterions affect contentWater, salt form and solvents change the as-is composition.
Storage needs a data basisShipping practice is not the same as stability evidence.
Evidence map
Research context
Published studies and regulatory records, not customer testimonials or usage guidance.
A multi-ingredient microneedle patch improved measured eye-area outcomes
Because several active components and a microneedle device were used, SNAP-8’s independent contribution was not isolated.
View primary recordWrinkle measures changed with a multi-ingredient patch regimen
The design supports the tested combination only, not standalone acetyl octapeptide-3.
View primary recordCurated references
Third-party publications selected for direct relevance.
-
01
24-subject combination study
Clinical evaluation of a dual anti-wrinkle dissolving microneedle patch
Shin JY, et al. Ann Dermatol. 2024. PMID 39082657.
-
02
12-week combination study
Clinical efficacy of a cosmetic dissolving microneedle patch
Combination-product study. 2019. PMID 31134751.
SNAP-8 questions
Concise answers for researchers comparing identity, evidence and catalog variants.
What is SNAP-8?
SNAP-8 (acetyl octapeptide-3) is a cosmetic peptide used in topical anti-wrinkle formulations. The cited human studies tested multi-ingredient microneedle patches, so improvements cannot be attributed to acetyl octapeptide-3 alone.
What evidence is available for SNAP-8?
Small human cosmetic studies exist for multi-ingredient delivery systems; direct monotherapy evidence is limited.
Does the cited research validate this catalog material?
No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.
Which quality documents can be requested?
A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.
How should SNAP-8 be stored?
Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.
Knowledge tools
Continue with structured evidence
Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.
Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.
Technical procurement
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Selected: NP810 · 10 mg × 10 vials