Cosmetic & Skin · Source-reviewed dossier
SNAP-8
Source-Reviewed Research Dossier
SNAP-8 is a short peptide used in skin and formulation research. Its design relates to a protein involved in how cells release signals, which explains interest in expression lines. The linked human work tested a microneedle patch containing several ingredients, rather than SNAP-8 alone. Changes in wrinkles, hydration or skin measures cannot therefore be assigned solely to the peptide. The patch and other ingredients are part of the tested intervention. Research ingredient identity and finished-product effects need separate evidence.
Compound overview
Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.
Product identity
- Product type
- Peptide research compound
- Catalog family
- SNAP-8
- Research category
- Cosmetic & Skin
- Catalog CAS RN
- 868844-74-0
- Catalog molecular formula
- C43H68N14O16S
- Catalog molecular weight
- 1075.15 g/mol
- Catalog sequence
- Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (Acetyl Octapeptide-3)
- Evidence status
- Combination-formula topical/microneedle evidence; standalone contribution is not isolated
- Intended use
- Research, development and manufacturing use only
Literature reference parameters
- Compound or material class
- Acetyl octapeptide-3 cosmetic peptideCatalog-family identity
- Evidence scope
- Combination-formula topical/microneedle evidence; standalone contribution is not isolatedDo not generalize beyond the cited model
- Source review
- Primary or authoritative records linked belowChecked 2026-09-01
Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.
How SNAP-8 is studied
A target-to-pathway view grounded in the linked research records.
Reported research findings
What published studies report about SNAP-8
Reported outcomes are paired with their experimental model and evidence boundary.
A multi-ingredient microneedle patch improved measured eye-area outcomes
The patch contained acetyl octapeptide-3, hyaluronic acid, vitamin-C derivative and cyclic lysophosphatidic acid; 24 healthy subjects were followed for 28 days.
Because several active components and a microneedle device were used, SNAP-8’s independent contribution was not isolated.
Read the primary studyWrinkle measures changed with a multi-ingredient patch regimen
A 12-week clinical study evaluated a dissolving microneedle patch containing acetyl octapeptide-3 with other cosmetic ingredients.
The design supports the tested combination only, not standalone acetyl octapeptide-3.
Read the primary studyCatalog options
Variant specifications
Pack-level catalog data; lot-level controls remain document-specific.
Specification & documents for NP810
Product specification
Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Lot documentation
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
Quality documentation
A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.
Analytical interpretation
Interpret the documents, not just the headline number.
Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.
Open the Quality & Documentation HubHPLC area ≠ assayA dominant peak does not establish target mass fraction.
Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.
Counterions affect contentWater, salt form and solvents change the as-is composition.
Storage needs a data basisShipping practice is not the same as stability evidence.
Evidence map
Research context
Published studies and regulatory records, not customer testimonials or usage guidance.
A multi-ingredient microneedle patch improved measured eye-area outcomes
Because several active components and a microneedle device were used, SNAP-8’s independent contribution was not isolated.
View primary recordWrinkle measures changed with a multi-ingredient patch regimen
The design supports the tested combination only, not standalone acetyl octapeptide-3.
View primary recordCurated references
Third-party publications selected for direct relevance.
-
01
24-subject combination study
Clinical evaluation of a dual anti-wrinkle dissolving microneedle patch
Shin JY, et al. Ann Dermatol. 2024. PMID 39082657.
-
02
12-week combination study
Clinical efficacy of a cosmetic dissolving microneedle patch
Combination-product study. 2019. PMID 31134751.
SNAP-8 questions
Concise answers for researchers comparing identity, evidence and catalog variants.
What effects are studied for SNAP-8?
The human studies tested microneedle patches containing SNAP-8 plus other actives. In the 24-person, 28-day study, the patch improved eye wrinkle appearance, reduced water loss, and increased elasticity and lifting compared with a placebo patch. The 12-week study found reduced fine lines and improved hydration, density, and thickness. These are combination-product findings, not proof of what SNAP-8 would do alone.
How should the SNAP-8 research findings be understood?
SNAP-8 in a research material is a research compound, not a cosmetic or medicine. Its identity and purity are set by the supplier's specification and lot documents, which the published clinical studies do not check. Results from a formulated patch do not carry over to a research material. Researchers using the raw peptide in cell or skin models are studying a different material than the one tested in people.
What evidence is available for SNAP-8?
Small human cosmetic studies exist for multi-ingredient delivery systems; direct monotherapy evidence is limited.
Does the cited research validate this catalog material?
No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.
Which quality documents can be requested?
A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.
How should SNAP-8 be stored?
Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.
Knowledge tools
Continue with structured evidence
Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.
Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.
Technical procurement
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Selected: NP810 · 10 mg × 10 vials