Gonadorelin is the native-sequence GnRH decapeptide with N-terminal pyroglutamate and C-terminal glycinamide. Both terminal modifications are identity-defining.
Evidence at a glance
- PubChem lists sequence pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2, formula C55H75N17O13 and molecular weight 1182.3 g/mol.
- The one-letter record XHWSYGLRPG uses X for pyroglutamate and does not by itself state the terminal amide.
- Gonadorelin acetate hydrate is a multicomponent record and must not be mass-equated with free Gonadorelin.
Identity record
N-terminal cyclization and C-terminal amidation change both mass and biological identity. Documentation should state the exact indexed form and not rely on “GnRH” alone.
Analytical and evidence boundary
An acetate hydrate record includes additional components. Lot calculations need stated counterion and water results if material is reported on an as-is basis.
Clinical effects of a regulated formulation and monitored delivery pattern do not establish identity, potency or sterility of catalog material.
Editorial rule
State the exact material, form, model or population and endpoint supported by the cited record. Do not convert mechanistic plausibility, an animal result, an official finished-drug label or an analytical test into a claim about an unrelated catalog lot.
Sources & editorial method
This article discusses the source records listed below, with the study models and limitations stated alongside the findings. AI-assisted drafting and image generation were used. The reference list identifies the records behind this article; it is not an independent peer review or verification of a supplied catalog lot.
4 linked records are listed in the references below. Read the editorial and AI-assistance policy.
How to interpret this article
Source-checked on 2026-09-02. Null results, sample size, model/population limits, finished-drug scope, regulatory status and product-evidence boundaries are retained. This is not medical advice, a customer case or validation of a catalog lot.
Research-use boundary: Catalog materials discussed on this website are for laboratory research, development and manufacturing use only, not for human or veterinary use. This content is not medical advice and does not provide administration instructions.
Primary records and authoritative sources
- Pituitary responsiveness to luteinizing-hormone releasing factorEarly human dose-response physiology; PMID 4599401.
- Pulsatile GnRH in hypothalamic amenorrheaHistorical 73-patient, 359-cycle series; PMID 8276957.
- PubChem Gonadorelin recordSequence, terminal chemistry, formula and molecular weight; CID 638793.
- WADA 2026 Prohibited ListOfficial list prohibits mechano growth factors.
Continue with structured records
Move from this editorial analysis to the product identity, filtered evidence and controlled terminology behind it.
