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Cosmetic & Skin · Source-reviewed dossier

Melanotan II

Source-Reviewed Research Dossier

Melanotan II is a cyclic α-MSH analogue acting at multiple melanocortin receptors. It is not an FDA-approved tanning medicine, and published reports include serious adverse events after unregulated use.

Research use only Lot documents on request
Melanotan II research product family with 1 catalog variants
AI-generated packaging mockup for catalog navigation. It is not a photograph of an actual supplied lot; container, label and presentation may vary.

Product family

Compound overview

Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; the current product specification and lot COA control.

Product identity

Product type
Peptide research compound
Catalog family
Melanotan II
Research category
Cosmetic & Skin
Catalog CAS RN
121062-08-6
Catalog molecular formula
C50H69N15O9
Catalog molecular weight
1024.18 g/mol
Catalog sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Evidence status
Human exposure reports and toxicity signals; no approved medicine
Intended use
Research, development and manufacturing use only

Literature reference parameters

Compound or material class
Nonselective cyclic melanocortin-receptor agonistCatalog-family identity
Evidence scope
Human exposure reports and toxicity signals; no approved medicineDo not generalize beyond the cited model
Source review
Primary or authoritative records linked belowChecked 2026-09-01

Identity safeguard Reference identifiers above describe the literature compound record. The supplied form, formula, molecular weight, purity and storage conditions must be verified against the product-specific specification and lot COA.

Mechanism of action

How Melanotan II is studied

A target-to-pathway view grounded in the linked research records.

Nonselective cyclic melanocortin-receptor agonist research basis

Nonselective melanocortin-receptor agonism can affect pigmentation, appetite, sexual response and cardiovascular/autonomic pathways.

Evidence and material boundary

Tanning or sexual-response observations do not establish a favorable benefit-risk profile; online products may also have uncertain identity and purity.

Reported research findings

What published studies report about Melanotan II

Reported outcomes are paired with their experimental model and evidence boundary.

Human toxicity report

Systemic toxicity and rhabdomyolysis were reported

A published case described systemic toxicity with rhabdomyolysis after Melanotan II use.

A case report cannot estimate incidence but identifies a credible serious-harm signal.

Read the primary study
Overdose case report

Priapism and sympathomimetic symptoms followed exposure

A clinical report documented prolonged priapism and systemic effects after Melanotan II overdose.

Unregulated product composition and dose add uncertainty rather than reassurance.

Read the primary study
Translation boundary: findings are limited to the evidence level stated on each card. Experimental protocol quantities are research details, not usage instructions.

Catalog options

Variant specifications

Pack-level catalog data; lot-level controls remain document-specific.

Catalog no.MT2
Pack size10 mg × 10 vials
Current variant
Specification & documents for MT2

Product specification

Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.

Lot documentation

Request by lot: CoA, HPLC purity and MS identity

Quality system

Quality documentation

Document availability is stated honestly and can vary by catalog variant or lot.

Lot-specific Certificate of AnalysisAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Product Specification SheetAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Analytical Method SummaryAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request

Analytical interpretation

Interpret the documents, not just the headline number.

Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.

Open the Quality & Documentation Hub

HPLC area ≠ assayA dominant peak does not establish target mass fraction.

Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.

Counterions affect contentWater, salt form and solvents change the as-is composition.

Storage needs a data basisShipping practice is not the same as stability evidence.

Evidence map

Research context

Published studies and regulatory records, not customer testimonials or usage guidance.

Human toxicity report

Systemic toxicity and rhabdomyolysis were reported

A case report cannot estimate incidence but identifies a credible serious-harm signal.

View primary record
Overdose case report

Priapism and sympathomimetic symptoms followed exposure

Unregulated product composition and dose add uncertainty rather than reassurance.

View primary record
Evidence boundary: each card states its evidence type. Human trials and regulatory records describe the studied or regulated intervention; preclinical records remain model-specific. None verifies the identity, quality, safety or efficacy of this catalog lot or provides usage instructions.

Literature basis

Curated references

Third-party publications selected for direct relevance.

  1. 01 Human toxicity report
  2. 02

    Melanotan II overdose and priapism

    Case report. 2013. PMID 23537392.

    Overdose case report

Research FAQ

Melanotan II questions

Concise answers for researchers comparing identity, evidence and catalog variants.

What is Melanotan II?

Melanotan II is a cyclic α-MSH analogue acting at multiple melanocortin receptors. It is not an FDA-approved tanning medicine, and published reports include serious adverse events after unregulated use.

What evidence is available for Melanotan II?

The human literature includes small experiments and case reports, with no approved product and meaningful safety uncertainty.

Does the cited research validate this catalog material?

No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.

Which quality documents can be requested?

A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.

How should Melanotan II be stored?

Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.

Knowledge center

Related insights

Owned educational content connected to this family.

Knowledge tools

Continue with structured evidence

Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.

Internal technical source review

Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.

Editorial status: NHD evidence editorial workflow · 2026-09-01 · Not independent medical review · Review policy

Technical procurement

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Selected: MT2 · 10 mg × 10 vials