Literature and evidence database
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Evidence records
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PubChem Compound Summary for CID 950107: 5-Amino-1-methylquinolinium
National Center for Biotechnology Information. PubChem CID 950107; record modified July 25, 2026.
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
Awosemo O, et al. Journal of Pharmaceutical and Biomedical Analysis. 2021;204:114255. PMID 34304009 · DOI 10.1016/j.jpba.2021.114255
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
Neelakantan H, et al. Biochemical Pharmacology. 2019. PMID 30753815 · DOI 10.1016/j.bcp.2019.02.008
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Neelakantan H, et al. Biochemical Pharmacology. 2018;147:141–152. PMID 29155147 · DOI 10.1016/j.bcp.2017.11.007
Small-molecule inhibitors of nicotinamide N-methyltransferase
J. Med. Chem. 2017. PMID 28548833 · DOI 10.1021/acs.jmedchem.7b00389.
ICH Q2(R2): Validation of Analytical Procedures
Official analytical-validation framework; not evidence that a specific catalog lot has been tested.
ICH Q14: Analytical Procedure Development
Official analytical-development framework; included as general method guidance only.
Editorial methodology
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Records are deduplicated by source URL and linked to every relevant product family. Study type and model are inferred from the citation and editorial evidence label, then reviewed during content QA.
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Labels and databases supporting regulatory status, formulation or chemical identity.
Controlled trials, systematic reviews and other clinical records with population-specific interpretation.
Animal, cell, analytical and mechanistic records that cannot establish human outcomes.
Narrative reviews, registries and sponsor reports kept visibly distinct from peer-reviewed outcomes.
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