NHD Global
Cognitive & Neuropeptides · Source-reviewed dossier
Source-Reviewed Research Dossier
DSIP stands for delta sleep-inducing peptide. It is a short chain of amino acids, the building blocks of proteins. It was found in the 1970s in blood draining from rabbit brains and was first suggested as a sleep-promoting factor. Later research could not confirm a DSIP gene, a natural precursor protein, or a specific receptor in the body. Its natural role is still unclear. One animal study reported that DSIP and a modified version reduced seizures in rats. Researchers study DSIP to understand neuropeptides, small signaling molecules in the brain. This catalog material is for laboratory research only, not for human use.
Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; request the applicable product specification and ask which lot records are available before ordering.
Product identity
Literature reference parameters
Identity safeguard Reference identifiers above describe the literature compound record. Confirm the supplied form, formula, molecular weight, purity and storage conditions against the applicable product specification and any available lot records.
A target-to-pathway view grounded in the linked research records.
Reported research findings
Reported outcomes are paired with their experimental model and evidence boundary.
A 2006 review concluded that fundamental questions about DSIP identity and physiological function remained unsettled.
The uncertainty argues against definitive sleep or treatment claims.
Read the primary studyA 2005 study evaluated DSIP and an analogue in metaphit-provoked seizures in rats.
A seizure model does not establish human sleep efficacy.
Read the primary studyCatalog options
Pack-level catalog data; lot-level controls remain document-specific.
Single-component peptide · 2 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
Single-component peptide · 5 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.
Document availability and scope must be confirmed for this variant and lot in the written quotation. A catalog description is not a lot-specific test result.
A listed document is not proof of availability for this lot. Ask the team to confirm the current COA status and the scope of any other records before ordering.
Analytical interpretation
Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.
Open the Quality & Documentation HubHPLC area ≠ assayA dominant peak does not establish target mass fraction.
Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.
Counterions affect contentWater, salt form and solvents change the as-is composition.
Storage needs a data basisShipping practice is not the same as stability evidence.
Evidence map
Published studies and regulatory records, not customer testimonials or usage guidance.
The uncertainty argues against definitive sleep or treatment claims.
View primary recordA seizure model does not establish human sleep efficacy.
View primary recordThird-party publications selected for direct relevance.
Graf MV, Kastin AJ. Peptides. 2006. PMID 16539679.
Preclinical study. 2005. PMID 15911358.
Concise answers for researchers comparing identity, evidence and catalog variants.
In a rat seizure model, DSIP and a modified version reduced how often, how severe, and how long seizures lasted after a chemical trigger. A separate review found that DSIP's natural identity, receptor, and sleep role remain unresolved. So the supported effects are limited to that animal model and do not extend to humans.
The available research includes one rat seizure study and one critical review. There are no human trials of DSIP as a finished medicine. Effects seen in rats cannot be assumed to apply to people for sleep, mood, or seizures. This catalog material is a research chemical with a defined identity, not a verified treatment.
The evidence is old, heterogeneous and largely preclinical, with substantial mechanistic uncertainty.
No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.
A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.
Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.
Knowledge center
Owned educational content connected to this family.
Delta sleep-inducing peptide has a memorable name, but the literature does not support treating that name as a settled mechanism or a proven human…
Updated October 1, 2026
DSIP is a defined nonapeptide also indexed as emideltide. The exact nine-residue sequence is clearer than its proposed endogenous mechanism.
Updated October 1, 2026Knowledge tools
Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.
Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.
Technical procurement
Selected: DS2 · 2 mg × 10 vials
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