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Longevity & Bioregulators · Source-reviewed dossier

Epitalon

Source-Reviewed Research Dossier

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide studied in cell-aging, telomere and animal reproductive-aging models. These experiments do not establish anti-aging, longevity or disease-treatment outcomes in humans.

Research use only Lot documents on request
Epitalon research product family with 2 catalog variants
AI-generated packaging mockup for catalog navigation. It is not a photograph of an actual supplied lot; container, label and presentation may vary.

Product family

Compound overview

Shared values below are consolidated from the current catalog record. They are not independent verification or lot results; the current product specification and lot COA control.

Product identity

Product type
Peptide research compound
Catalog family
Epitalon
Research category
Longevity & Bioregulators
Catalog CAS RN
307297-39-8
Catalog molecular formula
C14H22N4O9
Catalog molecular weight
390.35 g/mol
Catalog sequence
Ala-Glu-Asp-Gly
Evidence status
Cell and animal evidence; no established controlled human outcome evidence
Intended use
Research, development and manufacturing use only

Literature reference parameters

Compound or material class
Synthetic tetrapeptide bioregulatorCatalog-family identity
Evidence scope
Cell and animal evidence; no established controlled human outcome evidenceDo not generalize beyond the cited model
Source review
Primary or authoritative records linked belowChecked 2026-09-01

Identity safeguard Reference identifiers above describe the literature compound record. The supplied form, formula, molecular weight, purity and storage conditions must be verified against the product-specific specification and lot COA.

Mechanism of action

How Epitalon is studied

A target-to-pathway view grounded in the linked research records.

Synthetic tetrapeptide bioregulator research basis

Research hypotheses include effects on telomere-associated processes, oxidative state and cellular stress responses, but a single validated clinical mechanism has not been established.

Evidence and material boundary

Telomere measurements in cultured cells and outcomes in mouse oocytes cannot be translated into human lifespan or treatment claims.

Reported research findings

What published studies report about Epitalon

Reported outcomes are paired with their experimental model and evidence boundary.

Cell study

Telomere-related measurements were made in cultured human cells

A 2025 study evaluated epitalon exposure and telomere length across human cell lines.

An in-vitro cell-line result is not a human longevity outcome.

Read the primary study
Mouse-oocyte study

Post-ovulatory aging outcomes were preclinical

A 2022 study reported changes in oxidative-stress and developmental markers in aged mouse oocytes.

The exposure, species and reproductive model do not establish human effects.

Read the primary study
Translation boundary: findings are limited to the evidence level stated on each card. Experimental protocol quantities are research details, not usage instructions.

Catalog options

Variant specifications

Pack-level catalog data; lot-level controls remain document-specific.

Catalog no.ET10
Pack size10 mg × 10 vials
Specification & documents for ET10

Product specification

Single-component peptide · 10 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.

Lot documentation

Request by lot: CoA, HPLC purity and MS identity

Catalog no.ET50
Pack size50 mg × 10 vials
Specification & documents for ET50

Product specification

Single-component peptide · 50 mg/vial nominal · 10-vial pack · supplied form and release limits controlled by lot specification.

Lot documentation

Request by lot: CoA, HPLC purity and MS identity

Quality system

Quality documentation

Document availability is stated honestly and can vary by catalog variant or lot.

Lot-specific Certificate of AnalysisAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Product Specification SheetAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request
Analytical Method SummaryAvailability and scope must be confirmed for the selected catalog variant and lot
Confirm before ordering Request

Analytical interpretation

Interpret the documents, not just the headline number.

Use the source-reviewed guide to separate chromatographic area purity, quantitative assay, LC-MS identity, composition and stability evidence before comparing variants or requesting a lot record.

Open the Quality & Documentation Hub

HPLC area ≠ assayA dominant peak does not establish target mass fraction.

Intact mass ≠ full sequenceIdentity strength depends on resolution and orthogonal evidence.

Counterions affect contentWater, salt form and solvents change the as-is composition.

Storage needs a data basisShipping practice is not the same as stability evidence.

Evidence map

Research context

Published studies and regulatory records, not customer testimonials or usage guidance.

Cell study

Telomere-related measurements were made in cultured human cells

An in-vitro cell-line result is not a human longevity outcome.

View primary record
Mouse-oocyte study

Post-ovulatory aging outcomes were preclinical

The exposure, species and reproductive model do not establish human effects.

View primary record
Evidence boundary: each card states its evidence type. Human trials and regulatory records describe the studied or regulated intervention; preclinical records remain model-specific. None verifies the identity, quality, safety or efficacy of this catalog lot or provides usage instructions.

Literature basis

Curated references

Third-party publications selected for direct relevance.

  1. 01

    Epitalon and telomere length in human cell lines

    Cell study. 2025. PMID 40908429.

    Cell study
  2. 02

    Epitalon delays postovulatory aging of mouse oocytes

    Preclinical study. 2022. PMID 35413689.

    Mouse-oocyte study

Research FAQ

Epitalon questions

Concise answers for researchers comparing identity, evidence and catalog variants.

What is Epitalon?

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide studied in cell-aging, telomere and animal reproductive-aging models. These experiments do not establish anti-aging, longevity or disease-treatment outcomes in humans.

What evidence is available for Epitalon?

Direct records are predominantly laboratory and animal studies, with no adequate controlled human trial supporting broad longevity claims.

Does the cited research validate this catalog material?

No. The cited records describe their own intervention, formulation, model and controls. They do not verify the identity, purity, sterility, safety or efficacy of a catalog lot.

Which quality documents can be requested?

A lot-specific COA, product specification sheet and analytical method summary can be requested where applicable.

How should Epitalon be stored?

Store at -20 °C, protected from light and moisture. After reconstitution, aliquot and avoid repeated freeze-thaw cycles. Confirm the applicable storage statement on the product-specific specification and lot documentation.

Knowledge center

Related insights

Owned educational content connected to this family.

AI-generated illustration: cell biology laboratory scene for an Epitalon evidence review

Epitalon Evidence Review: Telomere Cell Data and Mouse Oocytes

Recent Epitalon papers report telomere-related changes in cultured cells and oxidative-stress findings in post-ovulatory mouse oocytes. Neither experiment demonstrates longer life, slower aging or…

Updated September 8, 2026
AI-generated illustration: HPLC laboratory scene for an Epitalon identity guide

Epitalon Identity Guide: AEDG Sequence, Mass and Evidence Boundary

Epitalon is the tetrapeptide Ala-Glu-Asp-Gly, abbreviated AEDG. Identity, sequence confirmation, chromatographic purity and quantitative peptide content are related but separate measurements.

Updated September 8, 2026

Knowledge tools

Continue with structured evidence

Move from this dossier into canonical evidence maps, verified status records, analytical interpretation and laboratory calculations.

Internal technical source review

Claims were checked against the linked primary publication, regulatory label or authoritative compound record. Published findings stay attached to their study model, formulation and route. Catalog identity and lot quality remain controlled by the applicable specification and lot-specific documents.

Editorial status: NHD evidence editorial workflow · 2026-09-01 · Not independent medical review · Review policy

Technical procurement

Ready to request a quote?

Selected: ET10 · 10 mg × 10 vials