Literature and evidence database
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FOXO4-DRI and endothelial-cell senescence
2026 endothelial and mouse-aging-model study; PMID 41625068.
FDA Drug Trials Snapshot: Forzinity
U.S. FDA. Approval date September 19, 2025; SPIBA-201 population and endpoint record.
PNC-27 experimental antitumor study
Preclinical study. 2025. PMID 40750238.
Epitalon and telomere length in human cell lines
Cell study. 2025. PMID 40908429.
TESTS phase 3 thymosin alpha-1 sepsis trial
Primary 2025 multicenter trial; PMID 39814420.
Thymalin in rat mandibular regeneration
Preclinical study. 2024. PMID 38642352.
PNC-27 membrane-associated anticancer research
Preclinical study. 2024. PMID 38802154.
Epitalon delays postovulatory aging of mouse oocytes
Preclinical study. 2022. PMID 35413689.
Nicotinamide adenine dinucleotide in cardiac remodeling and aging
Mini-review. 2022. PMID 35249481.
Elamipretide phase 2/3 trial in Barth syndrome
Reid Thompson W, et al. Genetics in Medicine. 2021. PMID 33077895.
Thymosin alpha 1: a comprehensive review of the literature
Dominari A, et al. World J Virol. 2020. PMID 33362999.
Thymalin and human hematopoietic stem cells
Cell study. 2020. PMID 33237528.
FOXO4-DRI and age-related Leydig-cell dysfunction
Preclinical study. 2020. PMID 31959736.
Thymosin alpha 1 treatment for patients with sepsis
Clinical review. 2018. PMID 30063866.
Targeted apoptosis of senescent cells restores tissue homeostasis
Baar MP, et al. Cell. 2017. PMID 28340339.
Pinealon in a prenatal hyperhomocysteinemia model
Preclinical study. 2012. PMID 22567179.
Pinealon effects on cell viability and proliferative processes
Cell study. 2011. PMID 21978084.
NAD+ metabolism and the control of energy homeostasis
Houtkooper RH, et al. Endocr Rev. 2010. PMID 19149596.
PubChem Epitalon record
Sequence, formula, molecular weight and synonyms; CID 219042.
NAD+ metabolism and energy homeostasis
Mechanistic review; PMID 26118927.
NAD+ metabolism and metabolic health translation
Review emphasizing the preclinical-to-human boundary; PMID 30772929.
PubChem oxidized NAD record
Nadide identity; CID 5892.
PubChem NADH record
Reduced-form identity; CID 439153.
2025 thymosin alpha-1 sepsis meta-analysis
Eleven RCTs with quality and trial-sequential analyses; PMID 40969554.
PubChem Thymalfasin record
Sequence, formula, mass and synonym record; CID 16130571.
FDA accelerated approval announcement for Forzinity
Approval scope and confirmatory requirement.
Editorial methodology
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Records are deduplicated by source URL and linked to every relevant product family. Study type and model are inferred from the citation and editorial evidence label, then reviewed during content QA.
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Labels and databases supporting regulatory status, formulation or chemical identity.
Controlled trials, systematic reviews and other clinical records with population-specific interpretation.
Animal, cell, analytical and mechanistic records that cannot establish human outcomes.
Narrative reviews, registries and sponsor reports kept visibly distinct from peer-reviewed outcomes.
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